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PUBMED FOR HANDHELDS

Journal Abstract Search


168 related items for PubMed ID: 10572005

  • 1. Interactions of the sponge-derived antimitotic tripeptide hemiasterlin with tubulin: comparison with dolastatin 10 and cryptophycin 1.
    Bai R, Durso NA, Sackett DL, Hamel E.
    Biochemistry; 1999 Oct 26; 38(43):14302-10. PubMed ID: 10572005
    [Abstract] [Full Text] [Related]

  • 2. Characterization of the interaction of cryptophycin 1 with tubulin: binding in the Vinca domain, competitive inhibition of dolastatin 10 binding, and an unusual aggregation reaction.
    Bai R, Schwartz RE, Kepler JA, Pettit GR, Hamel E.
    Cancer Res; 1996 Oct 01; 56(19):4398-406. PubMed ID: 8813133
    [Abstract] [Full Text] [Related]

  • 3. The spongistatins, potently cytotoxic inhibitors of tubulin polymerization, bind in a distinct region of the vinca domain.
    Bai R, Taylor GF, Cichacz ZA, Herald CL, Kepler JA, Pettit GR, Hamel E.
    Biochemistry; 1995 Aug 01; 34(30):9714-21. PubMed ID: 7626642
    [Abstract] [Full Text] [Related]

  • 4. Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel-Dreyer chromatography.
    Cruz-Monserrate Z, Mullaney JT, Harran PG, Pettit GR, Hamel E.
    Eur J Biochem; 2003 Sep 01; 270(18):3822-8. PubMed ID: 12950266
    [Abstract] [Full Text] [Related]

  • 5. Localization of the antimitotic peptide and depsipeptide binding site on beta-tubulin.
    Mitra A, Sept D.
    Biochemistry; 2004 Nov 09; 43(44):13955-62. PubMed ID: 15518544
    [Abstract] [Full Text] [Related]

  • 6. Differential effects of active isomers, segments, and analogs of dolastatin 10 on ligand interactions with tubulin. Correlation with cytotoxicity.
    Bai R, Roach MC, Jayaram SK, Barkoczy J, Pettit GR, Ludueña RF, Hamel E.
    Biochem Pharmacol; 1993 Apr 06; 45(7):1503-15. PubMed ID: 8471072
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  • 8. Characterization of the interaction of TZT-1027, a potent antitumor agent, with tubulin.
    Natsume T, Watanabe J, Tamaoki S, Fujio N, Miyasaka K, Kobayashi M.
    Jpn J Cancer Res; 2000 Jul 06; 91(7):737-47. PubMed ID: 10920282
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  • 10. Mechanism of action cryptophycin. Interaction with the Vinca alkaloid domain of tubulin.
    Smith CD, Zhang X.
    J Biol Chem; 1996 Mar 15; 271(11):6192-8. PubMed ID: 8626409
    [Abstract] [Full Text] [Related]

  • 11. Interaction of cryptophycin 1 with tubulin and microtubules.
    Kerksiek K, Mejillano MR, Schwartz RE, Georg GI, Himes RH.
    FEBS Lett; 1995 Dec 11; 377(1):59-61. PubMed ID: 8543019
    [Abstract] [Full Text] [Related]

  • 12. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites.
    Bai RL, Pettit GR, Hamel E.
    J Biol Chem; 1990 Oct 05; 265(28):17141-9. PubMed ID: 2211617
    [Abstract] [Full Text] [Related]

  • 13. Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain.
    Bai R, Pettit GR, Hamel E.
    Biochem Pharmacol; 1990 Jun 15; 39(12):1941-9. PubMed ID: 2353935
    [Abstract] [Full Text] [Related]

  • 14. Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules.
    Bai R, Friedman SJ, Pettit GR, Hamel E.
    Biochem Pharmacol; 1992 Jun 23; 43(12):2637-45. PubMed ID: 1632820
    [Abstract] [Full Text] [Related]

  • 15. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
    Bai R, Cichacz ZA, Herald CL, Pettit GR, Hamel E.
    Mol Pharmacol; 1993 Oct 23; 44(4):757-66. PubMed ID: 8232226
    [Abstract] [Full Text] [Related]

  • 16. Interaction of dolastatin 10 with tubulin: induction of aggregation and binding and dissociation reactions.
    Bai R, Taylor GF, Schmidt JM, Williams MD, Kepler JA, Pettit GR, Hamel E.
    Mol Pharmacol; 1995 May 23; 47(5):965-76. PubMed ID: 7746283
    [Abstract] [Full Text] [Related]

  • 17. Direct photoaffinity labeling by dolastatin 10 of the amino-terminal peptide of beta-tubulin containing cysteine 12.
    Bai R, Covell DG, Taylor GF, Kepler JA, Copeland TD, Nguyen NY, Pettit GR, Hamel E.
    J Biol Chem; 2004 Jul 16; 279(29):30731-40. PubMed ID: 15123603
    [Abstract] [Full Text] [Related]

  • 18. Cryptophycin 1 binds to tubulin at a site distinct from the colchicine binding site and at a site that may overlap the vinca binding site.
    Mooberry SL, Taoka CR, Busquets L.
    Cancer Lett; 1996 Oct 01; 107(1):53-7. PubMed ID: 8913266
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  • 20. Interaction of diazonamide A with tubulin.
    Bai R, Cruz-Monserrate Z, Fenical W, Pettit GR, Hamel E.
    Arch Biochem Biophys; 2020 Feb 15; 680():108217. PubMed ID: 31830440
    [Abstract] [Full Text] [Related]


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