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Journal Abstract Search
272 related items for PubMed ID: 10581253
1. Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein. Blott EJ, Higgins CF, Linton KJ. EMBO J; 1999 Dec 01; 18(23):6800-8. PubMed ID: 10581253 [Abstract] [Full Text] [Related]
3. Membrane-integration characteristics of two ABC transporters, CFTR and P-glycoprotein. Enquist K, Fransson M, Boekel C, Bengtsson I, Geiger K, Lang L, Pettersson A, Johansson S, von Heijne G, Nilsson I. J Mol Biol; 2009 Apr 17; 387(5):1153-64. PubMed ID: 19236881 [Abstract] [Full Text] [Related]
4. Structure of the human multidrug resistance protein 1 nucleotide binding domain 1 bound to Mg2+/ATP reveals a non-productive catalytic site. Ramaen O, Leulliot N, Sizun C, Ulryck N, Pamlard O, Lallemand JY, Tilbeurgh Hv, Jacquet E. J Mol Biol; 2006 Jun 16; 359(4):940-9. PubMed ID: 16697012 [Abstract] [Full Text] [Related]
6. The conserved tyrosine residues 401 and 1044 in ATP sites of human P-glycoprotein are critical for ATP binding and hydrolysis: evidence for a conserved subdomain, the A-loop in the ATP-binding cassette. Kim IW, Peng XH, Sauna ZE, FitzGerald PC, Xia D, Müller M, Nandigama K, Ambudkar SV. Biochemistry; 2006 Jun 20; 45(24):7605-16. PubMed ID: 16768456 [Abstract] [Full Text] [Related]
7. Mutagenesis of transmembrane domain 11 of P-glycoprotein by alanine scanning. Hanna M, Brault M, Kwan T, Kast C, Gros P. Biochemistry; 1996 Mar 19; 35(11):3625-35. PubMed ID: 8639515 [Abstract] [Full Text] [Related]
8. Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux. Loo TW, Clarke DM. J Membr Biol; 2005 Aug 19; 206(3):173-85. PubMed ID: 16456713 [Abstract] [Full Text] [Related]
9. Mechanism of ABC transporters: a molecular dynamics simulation of a well characterized nucleotide-binding subunit. Jones PM, George AM. Proc Natl Acad Sci U S A; 2002 Oct 01; 99(20):12639-44. PubMed ID: 12237398 [Abstract] [Full Text] [Related]
10. The extracellular loop between TM5 and TM6 of P-glycoprotein is required for reactivity with monoclonal antibody UIC2. Zhou Y, Gottesman MM, Pastan I. Arch Biochem Biophys; 1999 Jul 01; 367(1):74-80. PubMed ID: 10375401 [Abstract] [Full Text] [Related]
11. Functional role of the linker region in purified human P-glycoprotein. Sato T, Kodan A, Kimura Y, Ueda K, Nakatsu T, Kato H. FEBS J; 2009 Jul 01; 276(13):3504-16. PubMed ID: 19490125 [Abstract] [Full Text] [Related]
12. Structure of multidrug-resistance proteins of the ATP-binding cassette (ABC) superfamily. Altenberg GA. Curr Med Chem Anticancer Agents; 2004 Jan 01; 4(1):53-62. PubMed ID: 14754412 [Abstract] [Full Text] [Related]
13. Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoprotein. Lawson J, O'Mara ML, Kerr ID. Biochim Biophys Acta; 2008 Feb 01; 1778(2):376-91. PubMed ID: 18035039 [Abstract] [Full Text] [Related]
14. Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis. Jha S, Karnani N, Dhar SK, Mukhopadhayay K, Shukla S, Saini P, Mukhopadhayay G, Prasad R. Biochemistry; 2003 Sep 16; 42(36):10822-32. PubMed ID: 12962507 [Abstract] [Full Text] [Related]
15. A model for the nucleotide-binding domains of ABC transporters based on the large domain of aspartate aminotransferase. Hoedemaeker FJ, Davidson AR, Rose DR. Proteins; 1998 Feb 15; 30(3):275-86. PubMed ID: 9517543 [Abstract] [Full Text] [Related]
16. Functional asymmetry of the ATP-binding-cassettes of the ABC transporter TAP is determined by intrinsic properties of the nucleotide binding domains. Daumke O, Knittler MR. Eur J Biochem; 2001 Sep 15; 268(17):4776-86. PubMed ID: 11532014 [Abstract] [Full Text] [Related]
17. Interaction of transported drugs with the lipid bilayer and P-glycoprotein through a solvation exchange mechanism. Omote H, Al-Shawi MK. Biophys J; 2006 Jun 01; 90(11):4046-59. PubMed ID: 16565061 [Abstract] [Full Text] [Related]
18. Conformational changes of the bacterial type I ATP-binding cassette importer HisQMP2 at distinct steps of the catalytic cycle. Heuveling J, Frochaux V, Ziomkowska J, Wawrzinek R, Wessig P, Herrmann A, Schneider E. Biochim Biophys Acta; 2014 Jan 01; 1838(1 Pt B):106-16. PubMed ID: 24021237 [Abstract] [Full Text] [Related]
19. Crystal structure of the ATP-binding subunit of an ABC transporter. Hung LW, Wang IX, Nikaido K, Liu PQ, Ames GF, Kim SH. Nature; 1998 Dec 17; 396(6712):703-7. PubMed ID: 9872322 [Abstract] [Full Text] [Related]
20. Mutation of the aromatic amino acid interacting with adenine moiety of ATP to a polar residue alters the properties of multidrug resistance protein 1. Zhao Q, Chang XB. J Biol Chem; 2004 Nov 19; 279(47):48505-12. PubMed ID: 15355964 [Abstract] [Full Text] [Related] Page: [Next] [New Search]