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Journal Abstract Search


272 related items for PubMed ID: 10581253

  • 1. Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein.
    Blott EJ, Higgins CF, Linton KJ.
    EMBO J; 1999 Dec 01; 18(23):6800-8. PubMed ID: 10581253
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  • 3. Membrane-integration characteristics of two ABC transporters, CFTR and P-glycoprotein.
    Enquist K, Fransson M, Boekel C, Bengtsson I, Geiger K, Lang L, Pettersson A, Johansson S, von Heijne G, Nilsson I.
    J Mol Biol; 2009 Apr 17; 387(5):1153-64. PubMed ID: 19236881
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  • 4. Structure of the human multidrug resistance protein 1 nucleotide binding domain 1 bound to Mg2+/ATP reveals a non-productive catalytic site.
    Ramaen O, Leulliot N, Sizun C, Ulryck N, Pamlard O, Lallemand JY, Tilbeurgh Hv, Jacquet E.
    J Mol Biol; 2006 Jun 16; 359(4):940-9. PubMed ID: 16697012
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  • 6. The conserved tyrosine residues 401 and 1044 in ATP sites of human P-glycoprotein are critical for ATP binding and hydrolysis: evidence for a conserved subdomain, the A-loop in the ATP-binding cassette.
    Kim IW, Peng XH, Sauna ZE, FitzGerald PC, Xia D, Müller M, Nandigama K, Ambudkar SV.
    Biochemistry; 2006 Jun 20; 45(24):7605-16. PubMed ID: 16768456
    [Abstract] [Full Text] [Related]

  • 7. Mutagenesis of transmembrane domain 11 of P-glycoprotein by alanine scanning.
    Hanna M, Brault M, Kwan T, Kast C, Gros P.
    Biochemistry; 1996 Mar 19; 35(11):3625-35. PubMed ID: 8639515
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  • 8. Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux.
    Loo TW, Clarke DM.
    J Membr Biol; 2005 Aug 19; 206(3):173-85. PubMed ID: 16456713
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  • 9. Mechanism of ABC transporters: a molecular dynamics simulation of a well characterized nucleotide-binding subunit.
    Jones PM, George AM.
    Proc Natl Acad Sci U S A; 2002 Oct 01; 99(20):12639-44. PubMed ID: 12237398
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  • 10. The extracellular loop between TM5 and TM6 of P-glycoprotein is required for reactivity with monoclonal antibody UIC2.
    Zhou Y, Gottesman MM, Pastan I.
    Arch Biochem Biophys; 1999 Jul 01; 367(1):74-80. PubMed ID: 10375401
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  • 11. Functional role of the linker region in purified human P-glycoprotein.
    Sato T, Kodan A, Kimura Y, Ueda K, Nakatsu T, Kato H.
    FEBS J; 2009 Jul 01; 276(13):3504-16. PubMed ID: 19490125
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  • 12. Structure of multidrug-resistance proteins of the ATP-binding cassette (ABC) superfamily.
    Altenberg GA.
    Curr Med Chem Anticancer Agents; 2004 Jan 01; 4(1):53-62. PubMed ID: 14754412
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  • 13. Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoprotein.
    Lawson J, O'Mara ML, Kerr ID.
    Biochim Biophys Acta; 2008 Feb 01; 1778(2):376-91. PubMed ID: 18035039
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  • 14. Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis.
    Jha S, Karnani N, Dhar SK, Mukhopadhayay K, Shukla S, Saini P, Mukhopadhayay G, Prasad R.
    Biochemistry; 2003 Sep 16; 42(36):10822-32. PubMed ID: 12962507
    [Abstract] [Full Text] [Related]

  • 15. A model for the nucleotide-binding domains of ABC transporters based on the large domain of aspartate aminotransferase.
    Hoedemaeker FJ, Davidson AR, Rose DR.
    Proteins; 1998 Feb 15; 30(3):275-86. PubMed ID: 9517543
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  • 16. Functional asymmetry of the ATP-binding-cassettes of the ABC transporter TAP is determined by intrinsic properties of the nucleotide binding domains.
    Daumke O, Knittler MR.
    Eur J Biochem; 2001 Sep 15; 268(17):4776-86. PubMed ID: 11532014
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  • 17. Interaction of transported drugs with the lipid bilayer and P-glycoprotein through a solvation exchange mechanism.
    Omote H, Al-Shawi MK.
    Biophys J; 2006 Jun 01; 90(11):4046-59. PubMed ID: 16565061
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  • 18. Conformational changes of the bacterial type I ATP-binding cassette importer HisQMP2 at distinct steps of the catalytic cycle.
    Heuveling J, Frochaux V, Ziomkowska J, Wawrzinek R, Wessig P, Herrmann A, Schneider E.
    Biochim Biophys Acta; 2014 Jan 01; 1838(1 Pt B):106-16. PubMed ID: 24021237
    [Abstract] [Full Text] [Related]

  • 19. Crystal structure of the ATP-binding subunit of an ABC transporter.
    Hung LW, Wang IX, Nikaido K, Liu PQ, Ames GF, Kim SH.
    Nature; 1998 Dec 17; 396(6712):703-7. PubMed ID: 9872322
    [Abstract] [Full Text] [Related]

  • 20. Mutation of the aromatic amino acid interacting with adenine moiety of ATP to a polar residue alters the properties of multidrug resistance protein 1.
    Zhao Q, Chang XB.
    J Biol Chem; 2004 Nov 19; 279(47):48505-12. PubMed ID: 15355964
    [Abstract] [Full Text] [Related]


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