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Journal Abstract Search


208 related items for PubMed ID: 10582136

  • 1. Tirapazamine: a new drug producing tumor specific enhancement of platinum-based chemotherapy in non-small-cell lung cancer.
    Wouters BG, Wang LH, Brown JM.
    Ann Oncol; 1999; 10 Suppl 5():S29-33. PubMed ID: 10582136
    [Abstract] [Full Text] [Related]

  • 2. Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors: its independence of p53 status.
    Masunaga S, Ono K, Takahashi A, Ohnishi K, Ohnishi T, Suzuki M, Nagata K, Kinashi Y, Nagasawa H, Uto Y, Hori H.
    Cancer Sci; 2003 Jan; 94(1):125-33. PubMed ID: 12708486
    [Abstract] [Full Text] [Related]

  • 3. Cisplatin anti-tumour potentiation by tirapazamine results from a hypoxia-dependent cellular sensitization to cisplatin.
    Kovacs MS, Hocking DJ, Evans JW, Siim BG, Wouters BG, Brown JM.
    Br J Cancer; 1999 Jun; 80(8):1245-51. PubMed ID: 10376978
    [Abstract] [Full Text] [Related]

  • 4. Combined effects of tirapazamine and mild hyperthermia on anti-angiogenic agent (TNP-470) treated tumors-reference to the effect on intratumor quiescent cells.
    Masunaga S, Ono K, Nishimura Y, Kanamori S, Saga T, Suzuki M, Kinashi Y, Takagaki M, Kasai S, Nagasawa H, Uto Y, Hori H.
    Int J Radiat Oncol Biol Phys; 2000 Jun 01; 47(3):799-807. PubMed ID: 10837967
    [Abstract] [Full Text] [Related]

  • 5. DNA damage measured by the comet assay in head and neck cancer patients treated with tirapazamine.
    Dorie MJ, Kovacs MS, Gabalski EC, Adam M, Le QT, Bloch DA, Pinto HA, Terris DJ, Brown JM.
    Neoplasia; 1999 Nov 01; 1(5):461-7. PubMed ID: 10933062
    [Abstract] [Full Text] [Related]

  • 6. Modification of the antitumor activity of chemotherapeutic drugs by the hypoxic cytotoxic agent tirapazamine.
    Dorie MJ, Brown JM.
    Cancer Chemother Pharmacol; 1997 Nov 01; 39(4):361-6. PubMed ID: 9025778
    [Abstract] [Full Text] [Related]

  • 7. An investigation of the molecular basis for the synergistic interaction of tirapazamine and cisplatin.
    Goldberg Z, Evans J, Birrell G, Brown JM.
    Int J Radiat Oncol Biol Phys; 2001 Jan 01; 49(1):175-82. PubMed ID: 11163512
    [Abstract] [Full Text] [Related]

  • 8. Enhancement of cisplatin sensitivity of quiescent cells in solid tumors by combined treatment with tirapazamine and low-temperature hyperthermia.
    Masunaga S, Ono K, Hori H, Akaboshi M, Kawai K, Suzuki M, Kinashi Y, Kasai S, Nagasawa H, Uto Y.
    Radiat Med; 1998 Jan 01; 16(6):441-8. PubMed ID: 9929144
    [Abstract] [Full Text] [Related]

  • 9. Tirapazamine: a hypoxia-activated topoisomerase II poison.
    Peters KB, Brown JM.
    Cancer Res; 2002 Sep 15; 62(18):5248-53. PubMed ID: 12234992
    [Abstract] [Full Text] [Related]

  • 10. Does reductive metabolism predict response to tirapazamine (SR 4233) in human non-small-cell lung cancer cell lines?
    Chinje EC, Patterson AV, Saunders MP, Lockyer SD, Harris AL, Stratford IJ.
    Br J Cancer; 1999 Dec 15; 81(7):1127-33. PubMed ID: 10584872
    [Abstract] [Full Text] [Related]

  • 11. Tirapazamine-induced cytotoxicity and DNA damage in transplanted tumors: relationship to tumor hypoxia.
    Siim BG, Menke DR, Dorie MJ, Brown JM.
    Cancer Res; 1997 Jul 15; 57(14):2922-8. PubMed ID: 9230202
    [Abstract] [Full Text] [Related]

  • 12. Selective potentiation of the hypoxic cytotoxicity of tirapazamine by its 1-N-oxide metabolite SR 4317.
    Siim BG, Pruijn FB, Sturman JR, Hogg A, Hay MP, Brown JM, Wilson WR.
    Cancer Res; 2004 Jan 15; 64(2):736-42. PubMed ID: 14744792
    [Abstract] [Full Text] [Related]

  • 13. Evaluation of the potential of hexamethylenetetramine, compared with tirapazamine, as a combined agent with {gamma}-irradiation and cisplatin treatment in vivo.
    Masunaga S, Tano K, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K, Nakamura J.
    Br J Radiol; 2009 May 15; 82(977):392-400. PubMed ID: 19153181
    [Abstract] [Full Text] [Related]

  • 14. Synergistic enhancement of the antitumor effect of taxol by the bioreductive compound NLCQ-1, in vivo: comparison with tirapazamine.
    Papadopoulou MV, Ji M, Bloomer WD.
    Oncol Res; 2002 May 15; 13(1):47-54. PubMed ID: 12201674
    [Abstract] [Full Text] [Related]

  • 15. Tirapazamine-cisplatin: the synergy.
    Gatzemeier U, Rodriguez G, Treat J, Miller V, von Roemeling R, Viallet J, Rey A.
    Br J Cancer; 1998 Jun 15; 77 Suppl 4(Suppl 4):15-7. PubMed ID: 9647615
    [Abstract] [Full Text] [Related]

  • 16. Potentiation of alkylating agents by NLCQ-1 or TPZ in vitro and in vivo.
    Papadopoulou MV, Ji X, Bloomer WD.
    J Exp Ther Oncol; 2006 Jun 15; 5(4):261-72. PubMed ID: 17024967
    [Abstract] [Full Text] [Related]

  • 17. Adaptation of human tumor cells to tirapazamine under aerobic conditions: implications of increased antioxidant enzyme activity to mechanism of aerobic cytotoxicity.
    Elwell JH, Siim BG, Evans JW, Brown JM.
    Biochem Pharmacol; 1997 Jul 15; 54(2):249-57. PubMed ID: 9271329
    [Abstract] [Full Text] [Related]

  • 18. Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs.
    Hicks KO, Pruijn FB, Secomb TW, Hay MP, Hsu R, Brown JM, Denny WA, Dewhirst MW, Wilson WR.
    J Natl Cancer Inst; 2006 Aug 16; 98(16):1118-28. PubMed ID: 16912264
    [Abstract] [Full Text] [Related]

  • 19. Tirapazamine cytotoxicity for neuroblastoma is p53 dependent.
    Yang B, Reynolds CP.
    Clin Cancer Res; 2005 Apr 01; 11(7):2774-80. PubMed ID: 15814660
    [Abstract] [Full Text] [Related]

  • 20. Photodynamic Therapy with Liposomal Zinc Phthalocyanine and Tirapazamine Increases Tumor Cell Death via DNA Damage.
    Broekgaarden M, Weijer R, van Wijk AC, Cox RC, Egmond MR, Hoebe R, van Gulik TM, Heger M.
    J Biomed Nanotechnol; 2017 Feb 01; 13(2):204-20. PubMed ID: 29377650
    [Abstract] [Full Text] [Related]


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