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Journal Abstract Search

141 related items for PubMed ID: 10585211

  • 1. Benzimidazole derivatives. 2. Synthesis and structure-activity relationships of new azabicyclic benzimidazole-4-carboxylic acid derivatives with affinity for serotoninergic 5-HT(3) receptors.
    López-Rodríguez ML, Benhamú B, Morcillo MJ, Tejada ID, Orensanz L, Alfaro MJ, Martín MI.
    J Med Chem; 1999 Dec 02; 42(24):5020-8. PubMed ID: 10585211
    [Abstract] [Full Text] [Related]

  • 2. Benzimidazole derivatives. Part 1: Synthesis and structure-activity relationships of new benzimidazole-4-carboxamides and carboxylates as potent and selective 5-HT4 receptor antagonists.
    López-Rodríguez ML, Benhamú B, Viso A, Morcillo MJ, Murcia M, Orensanz L, Alfaro MJ, Martín MI.
    Bioorg Med Chem; 1999 Nov 02; 7(11):2271-81. PubMed ID: 10632037
    [Abstract] [Full Text] [Related]

  • 3. 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.
    Tapia I, Alonso-Cires L, López-Tudanca PL, Mosquera R, Labeaga L, Innerárity A, Orjales A.
    J Med Chem; 1999 Jul 29; 42(15):2870-80. PubMed ID: 10425096
    [Abstract] [Full Text] [Related]

  • 4. Benzimidazole derivatives. Part 5: design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.
    López-Rodríguez ML, Benhamú B, Morcillo MJ, Tejada I, Avila D, Marco I, Schiapparelli L, Frechilla D, Del Río J.
    Bioorg Med Chem; 2004 Oct 01; 12(19):5181-91. PubMed ID: 15351401
    [Abstract] [Full Text] [Related]

  • 5. Benzimidazole derivatives. 3. 3D-QSAR/CoMFA model and computational simulation for the recognition of 5-HT(4) receptor antagonists.
    López-Rodríguez ML, Murcia M, Benhamú B, Viso A, Campillo M, Pardo L.
    J Med Chem; 2002 Oct 24; 45(22):4806-15. PubMed ID: 12383006
    [Abstract] [Full Text] [Related]

  • 6. The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitro.
    Wong EH, Clark R, Leung E, Loury D, Bonhaus DW, Jakeman L, Parnes H, Whiting RL, Eglen RM.
    Br J Pharmacol; 1995 Feb 24; 114(4):851-9. PubMed ID: 7773546
    [Abstract] [Full Text] [Related]

  • 7. Selective 5-hydroxytryptamine3 (5-HT3) receptor blocking activity of KB-R6933, a novel benzimidazole derivative.
    Ozaki A, Fujishima Y, Sukamoto T.
    Jpn J Pharmacol; 1999 May 24; 80(1):25-32. PubMed ID: 10446753
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
    Hirokawa Y, Fujiwara I, Suzuki K, Harada H, Yoshikawa T, Yoshida N, Kato S.
    J Med Chem; 2003 Feb 27; 46(5):702-15. PubMed ID: 12593651
    [Abstract] [Full Text] [Related]

  • 9. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Niso M, Perrone R, Tortorella V.
    J Med Chem; 2004 Dec 16; 47(26):6616-24. PubMed ID: 15588097
    [Abstract] [Full Text] [Related]

  • 10. Studies on serotonin (5-HT)3-receptor antagonist effects of enantiomers of 4,5,6,7-tetrahydro-1H-benzimidazole derivatives.
    Kamato T, Ito H, Suzuki T, Miyata K, Honda K.
    Jpn J Pharmacol; 1995 Mar 16; 67(3):185-94. PubMed ID: 7630036
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of a new class of 2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid derivatives as highly potent 5-HT3 receptor antagonists.
    Turconi M, Nicola M, Quintero MG, Maiocchi L, Micheletti R, Giraldo E, Donetti A.
    J Med Chem; 1990 Aug 16; 33(8):2101-8. PubMed ID: 1695682
    [Abstract] [Full Text] [Related]

  • 12. Benzimidazole derivatives as new serotonin 5-HT6 receptor antagonists. Molecular mechanisms of receptor inactivation.
    de la Fuente T, Martín-Fontecha M, Sallander J, Benhamú B, Campillo M, Medina RA, Pellissier LP, Claeysen S, Dumuis A, Pardo L, López-Rodríguez ML.
    J Med Chem; 2010 Feb 11; 53(3):1357-69. PubMed ID: 20078106
    [Abstract] [Full Text] [Related]

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  • 15. Design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.
    López-Rodríguez ML, Benhamú B, Morcillo MJ, Tejada I, Avila D, Marco I, Schiapparelli L, Frechilla D, Del Río J.
    Bioorg Med Chem Lett; 2003 Oct 06; 13(19):3177-80. PubMed ID: 12951088
    [Abstract] [Full Text] [Related]

  • 16. Pharmacological analyses of endo-6-methoxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl-2,3-dihydro-2-oxo-1 H- benzimidazole-1-carboxylate hydrochloride (DAU 6285) at the 5-hydroxytryptamine4 receptor in the tunica muscularis mucosae of rat esophagus and ileum of guinea pig: role of endogenous 5-hydroxytryptamine.
    Waikar MV, Hegde SS, Ford AP, Clarke DE.
    J Pharmacol Exp Ther; 1993 Feb 06; 264(2):654-61. PubMed ID: 8437113
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and 5-HT3 receptor affinity of new quinolinecarboxylic acid derivatives.
    Orjales A, Alonso-Cires L, López-Tudanca PL, Tapia I, Labeaga L, Mosquera R.
    Drug Des Discov; 2000 Feb 06; 16(4):271-9. PubMed ID: 10807033
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  • 19. New selective and potent 5-HT(1B/1D) antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides.
    Liao Y, Böttcher H, Harting J, Greiner H, van Amsterdam C, Cremers T, Sundell S, März J, Rautenberg W, Wikström H.
    J Med Chem; 2000 Feb 10; 43(3):517-25. PubMed ID: 10669578
    [Abstract] [Full Text] [Related]

  • 20. Pyrroloquinoxaline derivatives as high-affinity and selective 5-HT(3) receptor agonists: synthesis, further structure-activity relationships, and biological studies.
    Campiani G, Morelli E, Gemma S, Nacci V, Butini S, Hamon M, Novellino E, Greco G, Cagnotto A, Goegan M, Cervo L, Dalla Valle F, Fracasso C, Caccia S, Mennini T.
    J Med Chem; 1999 Oct 21; 42(21):4362-79. PubMed ID: 10543880
    [Abstract] [Full Text] [Related]

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