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Journal Abstract Search

171 related items for PubMed ID: 10585950

  • 1.
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  • 2. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
    Grigorenko BL, Nemukhin AV, Shadrina MS, Topol IA, Burt SK.
    Proteins; 2007 Feb 01; 66(2):456-66. PubMed ID: 17094109
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  • 7. Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis.
    Schlichting I, Almo SC, Rapp G, Wilson K, Petratos K, Lentfer A, Wittinghofer A, Kabsch W, Pai EF, Petsko GA.
    Nature; 1990 May 24; 345(6273):309-15. PubMed ID: 2111463
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  • 8. Comparison of ras-p21 bound to GDP and GTP: differences in protein and ligand dynamics.
    Mello LV, van Aalten DM, Findlay JB.
    Protein Eng; 1997 Apr 24; 10(4):381-7. PubMed ID: 9194162
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  • 9. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
    Schweins T, Geyer M, Kalbitzer HR, Wittinghofer A, Warshel A.
    Biochemistry; 1996 Nov 12; 35(45):14225-31. PubMed ID: 8916907
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  • 10. High frequency (139.5 GHz) electron paramagnetic resonance characterization of Mn(II)-H2(17)O interactions in GDP and GTP forms of p21 ras.
    Bellew BF, Halkides CJ, Gerfen GJ, Griffin RG, Singel DJ.
    Biochemistry; 1996 Sep 17; 35(37):12186-93. PubMed ID: 8810926
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  • 11. Computational characterization of the chemical step in the GTP hydrolysis by Ras-GAP for the wild-type and G13V mutated Ras.
    Mironov VA, Khrenova MG, Lychko LA, Nemukhin AV.
    Proteins; 2015 Jun 17; 83(6):1046-53. PubMed ID: 25820867
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  • 13. What is the role of the helical domain of Gsalpha in the GTPase reaction?
    Shnerb T, Lin N, Shurki A.
    Biochemistry; 2007 Sep 25; 46(38):10875-85. PubMed ID: 17727271
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  • 14. Three-dimensional structure of p21H-ras and its implications.
    Wittinghofer F.
    Semin Cancer Biol; 1992 Aug 25; 3(4):189-98. PubMed ID: 1421163
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  • 15. Calculation of pathways for the conformational transition between the GTP- and GDP-bound states of the Ha-ras-p21 protein: calculations with explicit solvent simulations and comparison with calculations in vacuum.
    Diaz JF, Wroblowski B, Schlitter J, Engelborghs Y.
    Proteins; 1997 Jul 25; 28(3):434-51. PubMed ID: 9223188
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  • 16. On the mechanism of guanosine triphosphate hydrolysis in ras p21 proteins.
    Langen R, Schweins T, Warshel A.
    Biochemistry; 1992 Sep 22; 31(37):8691-6. PubMed ID: 1390653
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  • 17. Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: studies with a fluorescent GTP analogue.
    Moore KJ, Webb MR, Eccleston JF.
    Biochemistry; 1993 Jul 27; 32(29):7451-9. PubMed ID: 8338843
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  • 18. Dissection of the GTPase mechanism of Ras protein by MD analysis of Ras mutants.
    Friedman ZY, Devary Y.
    Proteins; 2005 May 15; 59(3):528-33. PubMed ID: 15789417
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  • 19. Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins.
    Schweins T, Geyer M, Scheffzek K, Warshel A, Kalbitzer HR, Wittinghofer A.
    Nat Struct Biol; 1995 Jan 15; 2(1):36-44. PubMed ID: 7719852
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  • 20. Prediction of the GTPase activities by using the semiempirical molecular orbital theory.
    Kinoshita H, Shimizu K.
    Bioorg Med Chem Lett; 1998 May 05; 8(9):1083-8. PubMed ID: 9871712
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