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772 related items for PubMed ID: 10597238

  • 1. Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells.
    Suzuki S, Higuchi M, Proske RJ, Oridate N, Hong WK, Lotan R.
    Oncogene; 1999 Nov 04; 18(46):6380-7. PubMed ID: 10597238
    [Abstract] [Full Text] [Related]

  • 2. Mediation of N-(4-hydoxyphenyl)retinamide-induced apoptosis in human cancer cells by different mechanisms.
    Sun SY, Li W, Yue P, Lippman SM, Hong WK, Lotan R.
    Cancer Res; 1999 May 15; 59(10):2493-8. PubMed ID: 10344763
    [Abstract] [Full Text] [Related]

  • 3. Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
    Izeradjene K, Douglas L, Tillman DM, Delaney AB, Houghton JA.
    Cancer Res; 2005 Aug 15; 65(16):7436-45. PubMed ID: 16103097
    [Abstract] [Full Text] [Related]

  • 4. Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants.
    He Y, Leung KW, Zhang YH, Duan S, Zhong XF, Jiang RZ, Peng Z, Tombran-Tink J, Ge J.
    Invest Ophthalmol Vis Sci; 2008 Apr 15; 49(4):1447-58. PubMed ID: 18385062
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of mitochondrial respiratory chain complex I by TNF results in cytochrome c release, membrane permeability transition, and apoptosis.
    Higuchi M, Proske RJ, Yeh ET.
    Oncogene; 1998 Nov 12; 17(19):2515-24. PubMed ID: 9824162
    [Abstract] [Full Text] [Related]

  • 6. PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation.
    Appierto V, Tiberio P, Villani MG, Cavadini E, Formelli F.
    Carcinogenesis; 2009 May 12; 30(5):824-31. PubMed ID: 19325135
    [Abstract] [Full Text] [Related]

  • 7. Involvement of Rac in fenretinide-induced apoptosis.
    Kadara H, Tahara E, Kim HJ, Lotan D, Myers J, Lotan R.
    Cancer Res; 2008 Jun 01; 68(11):4416-23. PubMed ID: 18519704
    [Abstract] [Full Text] [Related]

  • 8. Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain.
    Kruidering M, Van de Water B, de Heer E, Mulder GJ, Nagelkerke JF.
    J Pharmacol Exp Ther; 1997 Feb 01; 280(2):638-49. PubMed ID: 9023274
    [Abstract] [Full Text] [Related]

  • 9. N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells.
    Kim HJ, Chakravarti N, Oridate N, Choe C, Claret FX, Lotan R.
    Oncogene; 2006 May 04; 25(19):2785-94. PubMed ID: 16407847
    [Abstract] [Full Text] [Related]

  • 10. The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family.
    Boya P, Morales MC, Gonzalez-Polo RA, Andreau K, Gourdier I, Perfettini JL, Larochette N, Deniaud A, Baran-Marszak F, Fagard R, Feuillard J, Asumendi A, Raphael M, Pau B, Brenner C, Kroemer G.
    Oncogene; 2003 Sep 18; 22(40):6220-30. PubMed ID: 13679861
    [Abstract] [Full Text] [Related]

  • 11. Apoptosis induction by a novel anti-prostate cancer compound, BMD188 (a fatty acid-containing hydroxamic acid), requires the mitochondrial respiratory chain.
    Joshi B, Li L, Taffe BG, Zhu Z, Wahl S, Tian H, Ben-Josef E, Taylor JD, Porter AT, Tang DG.
    Cancer Res; 1999 Sep 01; 59(17):4343-55. PubMed ID: 10485482
    [Abstract] [Full Text] [Related]

  • 12. Activation of caspase-8 during N-(4-hydroxyphenyl)retinamide-induced apoptosis in Fas-defective hepatoma cells.
    You KR, Shin MN, Park RK, Lee SO, Kim DG.
    Hepatology; 2001 Dec 01; 34(6):1119-27. PubMed ID: 11732001
    [Abstract] [Full Text] [Related]

  • 13. N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines.
    Cuello M, Coats AO, Darko I, Ettenberg SA, Gardner GJ, Nau MM, Liu JR, Birrer MJ, Lipkowitz S.
    Cell Death Differ; 2004 May 01; 11(5):527-41. PubMed ID: 14765134
    [Abstract] [Full Text] [Related]

  • 14. Increased level of the p67phox subunit of NADPH oxidase by 4HPR in head and neck squamous carcinoma cells.
    Kim HJ, Oridate N, Lotan R.
    Int J Oncol; 2005 Sep 01; 27(3):787-90. PubMed ID: 16077929
    [Abstract] [Full Text] [Related]

  • 15. Induction of apoptosis by N-(4-hydroxyphenyl)retinamide and its association with reactive oxygen species, nuclear retinoic acid receptors, and apoptosis-related genes in human prostate carcinoma cells.
    Sun SY, Yue P, Lotan R.
    Mol Pharmacol; 1999 Mar 01; 55(3):403-10. PubMed ID: 10051523
    [Abstract] [Full Text] [Related]

  • 16. Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species.
    Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB.
    J Cell Sci; 2007 Dec 01; 120(Pt 23):4155-66. PubMed ID: 18032788
    [Abstract] [Full Text] [Related]

  • 17. The synthetic heteroarotinoid SHetA2 induces apoptosis in squamous carcinoma cells through a receptor-independent and mitochondria-dependent pathway.
    Chun KH, Benbrook DM, Berlin KD, Hong WK, Lotan R.
    Cancer Res; 2003 Jul 01; 63(13):3826-32. PubMed ID: 12839980
    [Abstract] [Full Text] [Related]

  • 18. Mediating of caspase-independent apoptosis by cadmium through the mitochondria-ROS pathway in MRC-5 fibroblasts.
    Shih CM, Ko WC, Wu JS, Wei YH, Wang LF, Chang EE, Lo TY, Cheng HH, Chen CT.
    J Cell Biochem; 2004 Feb 01; 91(2):384-97. PubMed ID: 14743397
    [Abstract] [Full Text] [Related]

  • 19. TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species.
    Jin S, Ray RM, Johnson LR.
    Am J Physiol Gastrointest Liver Physiol; 2008 Apr 01; 294(4):G928-37. PubMed ID: 18218673
    [Abstract] [Full Text] [Related]

  • 20. Reactive oxygen species regulate Bax translocation and mitochondrial transmembrane potential, a possible mechanism for enhanced TRAIL-induced apoptosis by CCCP.
    Chaudhari AA, Seol JW, Kim SJ, Lee YJ, Kang HS, Kim IS, Kim NS, Park SY.
    Oncol Rep; 2007 Jul 01; 18(1):71-6. PubMed ID: 17549348
    [Abstract] [Full Text] [Related]

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