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Journal Abstract Search

173 related items for PubMed ID: 10600112

  • 1. Reduction of furin-nicked Pseudomonas exotoxin A: an unfolding story.
    McKee ML, FitzGerald DJ.
    Biochemistry; 1999 Dec 14; 38(50):16507-13. PubMed ID: 10600112
    [Abstract] [Full Text] [Related]

  • 2. Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver.
    Chiron MF, Fryling CM, FitzGerald DJ.
    J Biol Chem; 1994 Jul 08; 269(27):18167-76. PubMed ID: 8027078
    [Abstract] [Full Text] [Related]

  • 3. Furin regulates both the activation of Pseudomonas exotoxin A and the Quantity of the toxin receptor expressed on target cells.
    Gu M, Gordon VM, Fitzgerald DJ, Leppla SH.
    Infect Immun; 1996 Feb 08; 64(2):524-7. PubMed ID: 8550202
    [Abstract] [Full Text] [Related]

  • 4. Furin-mediated cleavage of Pseudomonas exotoxin-derived chimeric toxins.
    Chiron MF, Fryling CM, FitzGerald D.
    J Biol Chem; 1997 Dec 12; 272(50):31707-11. PubMed ID: 9395513
    [Abstract] [Full Text] [Related]

  • 5. Furin activates Pseudomonas exotoxin A by specific cleavage in vivo and in vitro.
    Inocencio NM, Moehring JM, Moehring TJ.
    J Biol Chem; 1994 Dec 16; 269(50):31831-5. PubMed ID: 7989356
    [Abstract] [Full Text] [Related]

  • 6. Pseudomonas exotoxin exhibits increased sensitivity to furin when sequences at the cleavage site are mutated to resemble the arginine-rich loop of diphtheria toxin.
    Chiron MF, Ogata M, FitzGerald DJ.
    Mol Microbiol; 1996 Nov 16; 22(4):769-78. PubMed ID: 8951823
    [Abstract] [Full Text] [Related]

  • 7. Redirecting Pseudomonas exotoxin.
    FitzGerald D, Pastan I.
    Semin Cell Biol; 1991 Feb 16; 2(1):31-7. PubMed ID: 1954341
    [Abstract] [Full Text] [Related]

  • 8. Proteolytic cleavage of Pseudomonas aeruginosa exotoxin A in the presence of lipid bilayers of different composition.
    Nordera P, Menestrina G.
    FEBS Lett; 1998 Jan 16; 421(3):268-72. PubMed ID: 9468320
    [Abstract] [Full Text] [Related]

  • 9. Processing of Pseudomonas aeruginosa exotoxin A is dispensable for cell intoxication.
    Morlon-Guyot J, Méré J, Bonhoure A, Beaumelle B.
    Infect Immun; 2009 Jul 16; 77(7):3090-9. PubMed ID: 19380469
    [Abstract] [Full Text] [Related]

  • 10. Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases.
    Gordon VM, Klimpel KR, Arora N, Henderson MA, Leppla SH.
    Infect Immun; 1995 Jan 16; 63(1):82-7. PubMed ID: 7806387
    [Abstract] [Full Text] [Related]

  • 11. Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol.
    Ogata M, Fryling CM, Pastan I, FitzGerald DJ.
    J Biol Chem; 1992 Dec 15; 267(35):25396-401. PubMed ID: 1460035
    [Abstract] [Full Text] [Related]

  • 12. The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.
    Sarac MS, Cameron A, Lindberg I.
    Infect Immun; 2002 Dec 15; 70(12):7136-9. PubMed ID: 12438396
    [Abstract] [Full Text] [Related]

  • 13. Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity.
    Wedekind JE, Trame CB, Dorywalska M, Koehl P, Raschke TM, McKee M, FitzGerald D, Collier RJ, McKay DB.
    J Mol Biol; 2001 Dec 07; 314(4):823-37. PubMed ID: 11734000
    [Abstract] [Full Text] [Related]

  • 14. Protection of the Furin Cleavage Site in Low-Toxicity Immunotoxins Based on Pseudomonas Exotoxin A.
    Kaplan G, Lee F, Onda M, Kolyvas E, Bhardwaj G, Baker D, Pastan I.
    Toxins (Basel); 2016 Jul 25; 8(8):. PubMed ID: 27463727
    [Abstract] [Full Text] [Related]

  • 15. Characterization of a cellular protease that cleaves Pseudomonas exotoxin.
    Fryling C, Ogata M, FitzGerald D.
    Infect Immun; 1992 Feb 25; 60(2):497-502. PubMed ID: 1730481
    [Abstract] [Full Text] [Related]

  • 16. Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol.
    Ogata M, Chaudhary VK, Pastan I, FitzGerald DJ.
    J Biol Chem; 1990 Nov 25; 265(33):20678-85. PubMed ID: 2122978
    [Abstract] [Full Text] [Related]

  • 17. Mechanism of action of Pseudomonas exotoxin. Identification of a rate-limiting step.
    Zdanovsky AG, Chiron M, Pastan I, FitzGerald DJ.
    J Biol Chem; 1993 Oct 15; 268(29):21791-9. PubMed ID: 8408034
    [Abstract] [Full Text] [Related]

  • 18. Elevation of vacuolar pH inhibits the cytotoxic activity of furin-cleaved exotoxin A.
    Corboy MJ, Draper RK.
    Infect Immun; 1997 Jun 15; 65(6):2240-2. PubMed ID: 9169757
    [Abstract] [Full Text] [Related]

  • 19. Endoprotease PACE4 is Ca2+-dependent and temperature-sensitive and can partly rescue the phenotype of a furin-deficient cell strain.
    Sucic JF, Moehring JM, Inocencio NM, Luchini JW, Moehring TJ.
    Biochem J; 1999 May 01; 339 ( Pt 3)(Pt 3):639-47. PubMed ID: 10215603
    [Abstract] [Full Text] [Related]

  • 20. Generation of a potent chimeric toxin by replacement of domain III of Pseudomonas exotoxin with ricin A chain KDEL.
    Pitcher C, Roberts L, Fawell S, Zdanovsky AG, FitzGerald DJ, Lord JM.
    Bioconjug Chem; 1995 May 01; 6(5):624-9. PubMed ID: 8974463
    [Abstract] [Full Text] [Related]

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