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237 related items for PubMed ID: 10606773

  • 21. Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
    Zang Y, Wang WH, Wu SW, Ealick SE, Wang CC.
    J Biol Chem; 2005 Jun 10; 280(23):22318-25. PubMed ID: 15817485
    [Abstract] [Full Text] [Related]

  • 22. Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis.
    Bzowska A, Koellner G, Wielgus-Kutrowska B, Stroh A, Raszewski G, Holý A, Steiner T, Frank J.
    J Mol Biol; 2004 Sep 17; 342(3):1015-32. PubMed ID: 15342253
    [Abstract] [Full Text] [Related]

  • 23. Role of ionization of the phosphate cosubstrate on phosphorolysis by purine nucleoside phosphorylase (PNP) of bacterial (E. coli) and mammalian (human) origin.
    Modrak-Wójcik A, Kirilenko A, Shugar D, Kierdaszuk B.
    Eur Biophys J; 2008 Feb 17; 37(2):153-64. PubMed ID: 17639373
    [Abstract] [Full Text] [Related]

  • 24. Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
    Fedorov A, Shi W, Kicska G, Fedorov E, Tyler PC, Furneaux RH, Hanson JC, Gainsford GJ, Larese JZ, Schramm VL, Almo SC.
    Biochemistry; 2001 Jan 30; 40(4):853-60. PubMed ID: 11170405
    [Abstract] [Full Text] [Related]

  • 25. Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.
    Deng H, Lewandowicz A, Cahill SM, Furneaux RH, Tyler PC, Girvin ME, Callender RH, Schramm VL.
    Biochemistry; 2004 Feb 24; 43(7):1980-7. PubMed ID: 14967038
    [Abstract] [Full Text] [Related]

  • 26. Calf spleen purine nucleoside phosphorylase: complex kinetic mechanism, hydrolysis of 7-methylguanosine, and oligomeric state in solution.
    Bzowska A.
    Biochim Biophys Acta; 2002 Apr 29; 1596(2):293-317. PubMed ID: 12007610
    [Abstract] [Full Text] [Related]

  • 27. Studies of inhibitor binding to Escherichia coli purine nucleoside phosphorylase using the transferred nuclear Overhauser effect and rotating-frame nuclear Overhauser enhancement.
    Perlman ME, Davis DG, Koszalka GW, Tuttle JV, London RE.
    Biochemistry; 1994 Jun 21; 33(24):7547-59. PubMed ID: 8011620
    [Abstract] [Full Text] [Related]

  • 28. Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
    Shi W, Basso LA, Santos DS, Tyler PC, Furneaux RH, Blanchard JS, Almo SC, Schramm VL.
    Biochemistry; 2001 Jul 27; 40(28):8204-15. PubMed ID: 11444966
    [Abstract] [Full Text] [Related]

  • 29. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.
    Miles RW, Tyler PC, Furneaux RH, Bagdassarian CK, Schramm VL.
    Biochemistry; 1998 Jun 16; 37(24):8615-21. PubMed ID: 9628722
    [Abstract] [Full Text] [Related]

  • 30. Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum.
    Kicska GA, Tyler PC, Evans GB, Furneaux RH, Kim K, Schramm VL.
    J Biol Chem; 2002 Feb 01; 277(5):3219-25. PubMed ID: 11707439
    [Abstract] [Full Text] [Related]

  • 31. Synthesis of 6-aryloxy- and 6-arylalkoxy-2-chloropurines and their interactions with purine nucleoside phosphorylase from Escherichia coli.
    Bzowska A, Magnowska L, Kazimierczuk Z.
    Z Naturforsch C J Biosci; 1999 Dec 01; 54(12):1055-67. PubMed ID: 10685497
    [Abstract] [Full Text] [Related]

  • 32. Formycin B, purine nucleoside phosphorylase and lymphocyte function.
    Osborne WR, Sullivan JL, Scott CR.
    Immunol Commun; 1980 Dec 01; 9(3):257-67. PubMed ID: 6772548
    [Abstract] [Full Text] [Related]

  • 33. Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
    Tebbe J, Bzowska A, Wielgus-Kutrowska B, Schröder W, Kazimierczuk Z, Shugar D, Saenger W, Koellner G.
    J Mol Biol; 1999 Dec 17; 294(5):1239-55. PubMed ID: 10600382
    [Abstract] [Full Text] [Related]

  • 34. Tryptophan-free human PNP reveals catalytic site interactions.
    Ghanem M, Saen-oon S, Zhadin N, Wing C, Cahill SM, Schwartz SD, Callender R, Schramm VL.
    Biochemistry; 2008 Mar 11; 47(10):3202-15. PubMed ID: 18269249
    [Abstract] [Full Text] [Related]

  • 35. Kinetics of phosphorolysis of 3-(beta-D-ribofuranosyl)adenine and 3-(beta-D-ribofuranosyl)hypoxanthine, non-conventional substrates of purine-nucleoside phosphorylase.
    Bzowska A, Kulikowska E, Poopeiko NE, Shugar D.
    Eur J Biochem; 1996 Jul 01; 239(1):229-34. PubMed ID: 8706713
    [Abstract] [Full Text] [Related]

  • 36. Purine nucleoside phosphorylase: inhibition by purine N(7)- and N(9)-acyclonucleosides; and substrate properties of 7-beta-D-ribofuranosylguanine and 7-beta-D-ribofuranosylhypoxanthine.
    Bzowska A, Ananiev AV, Ramzaeva N, Alksins E, Maurins JA, Kulikowska E, Shugar D.
    Biochem Pharmacol; 1994 Aug 30; 48(5):937-47. PubMed ID: 8093106
    [Abstract] [Full Text] [Related]

  • 37. Probing the mechanism of purine nucleoside phosphorylase by steady-state kinetic studies and ligand binding characterization determined by fluorimetric titrations.
    Wielgus-Kutrowska B, Bzowska A.
    Biochim Biophys Acta; 2006 May 30; 1764(5):887-902. PubMed ID: 16631420
    [Abstract] [Full Text] [Related]

  • 38. Fluorescence emission properties of 8-azapurines and their nucleosides, and application to the kinetics of the reverse synthetic reaction of purine nucleoside phosphorylase.
    Wierzchowski J, Wielgus-Kutrowska B, Shugar D.
    Biochim Biophys Acta; 1996 May 21; 1290(1):9-17. PubMed ID: 8645713
    [Abstract] [Full Text] [Related]

  • 39. 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state.
    Chojnowski G, Breer K, Narczyk M, Wielgus-Kutrowska B, Czapinska H, Hashimoto M, Hikishima S, Yokomatsu T, Bochtler M, Girstun A, Staroń K, Bzowska A.
    Biochem Biophys Res Commun; 2010 Jan 01; 391(1):703-8. PubMed ID: 19944078
    [Abstract] [Full Text] [Related]

  • 40. Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.
    Luić M, Koellner G, Yokomatsu T, Shibuya S, Bzowska A.
    Acta Crystallogr D Biol Crystallogr; 2004 Aug 01; 60(Pt 8):1417-24. PubMed ID: 15272165
    [Abstract] [Full Text] [Related]

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