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266 related items for PubMed ID: 1061161

  • 1. Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells.
    Huberman E, Sachs L, Yang SK, Gelboin V.
    Proc Natl Acad Sci U S A; 1976 Feb; 73(2):607-11. PubMed ID: 1061161
    [Abstract] [Full Text] [Related]

  • 2. Inhibitory effect of 3-hydroxybenzo(a)pyrene on the mutagenicity and tumorigenicity of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Huang MT, Wood AW, Chang RL, Yagi H, Sayer JM, Jerina DM, Conney AH.
    Cancer Res; 1986 Feb; 46(2):558-66. PubMed ID: 3079665
    [Abstract] [Full Text] [Related]

  • 3. Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides.
    Thakker DR, Yagi H, Lu AY, Levin W, Conney AH.
    Proc Natl Acad Sci U S A; 1976 Oct; 73(10):3381-5. PubMed ID: 1068451
    [Abstract] [Full Text] [Related]

  • 4. Mutagenicity and cytotoxicity of benzo(a)pyrene benzo-ring epoxides.
    Wood AW, Wislocki PG, Chang RL, Levin W, Lu AY, Yagi J, Hernandez O, Herina DM, Conney AH.
    Cancer Res; 1976 Sep; 36(9 pt.1):3358-66. PubMed ID: 788899
    [Abstract] [Full Text] [Related]

  • 5. Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
    Buening MK, Wislocki PG, Levin W, Yagi H, Thakker DR, Akagi H, Koreeda M, Jerina DM, Conney AH.
    Proc Natl Acad Sci U S A; 1978 Nov; 75(11):5358-61. PubMed ID: 281685
    [Abstract] [Full Text] [Related]

  • 6. Identification of 7,12-dimethylbenz[a]anthracene metabolites that lead to mutagenesis in mammalian cells.
    Huberman E, Chou MW, Yang SK.
    Proc Natl Acad Sci U S A; 1979 Feb; 76(2):862-6. PubMed ID: 106395
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: exceptional activity of ellagic acid.
    Wood AW, Huang MT, Chang RL, Newmark HL, Lehr RE, Yagi H, Sayer JM, Jerina DM, Conney AH.
    Proc Natl Acad Sci U S A; 1982 Sep; 79(18):5513-7. PubMed ID: 6752950
    [Abstract] [Full Text] [Related]

  • 8. Mutagenicity of the bay-region diol-epoxides and other benzo-ring derivatives of dibenzo(a,h)pyrene and dibenzo(a,i)pyrene.
    Wood AW, Chang RL, Levin W, Ryan DE, Thomas PE, Lehr RE, Kumar S, Sardella DJ, Boger E, Yagi H, Sayer JM, Jerina DM, Conney AH.
    Cancer Res; 1981 Jul; 41(7):2589-97. PubMed ID: 7018665
    [Abstract] [Full Text] [Related]

  • 9. Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.
    Wood AW, Levin W, Lu AY, Yagi H, Hernandez O, Jerina DM, Conney AH.
    J Biol Chem; 1976 Aug 25; 251(16):4882-90. PubMed ID: 821945
    [Abstract] [Full Text] [Related]

  • 10. Species-specific enhancement by 7,8-benzoflavone of hepatic microsomal metabolism of benzo[e]pyrene 9,10-dihydrodiol to bay-region diol epoxides.
    Thakker DR, Levin W, Buening M, Yagi H, Lehr RE, Wood AW, Conney AH, Jerina DM.
    Cancer Res; 1981 Apr 25; 41(4):1389-96. PubMed ID: 7194138
    [Abstract] [Full Text] [Related]

  • 11. (+/-)-7alpha,8beta-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo(a)-pyrene is an intermediate in the metabolism and binding to DNA of benzo(a)pyrene.
    King HW, Osborne MR, Beland FA, Harvey RG, Brookes P.
    Proc Natl Acad Sci U S A; 1976 Aug 25; 73(8):2679-81. PubMed ID: 1066679
    [Abstract] [Full Text] [Related]

  • 12. Mutagenicity of isomeric diol-epoxides of benzo[a]pyrene and benz[a]anthracene in S. typhimurium TA98 and TA100 and in V79 Chinese hamster cells.
    Malaveille C, Kuroki T, Sims P, Grover PL, Bartsch H.
    Mutat Res; 1977 Sep 25; 44(3):313-26. PubMed ID: 333280
    [Abstract] [Full Text] [Related]

  • 13. Mutagenicity to mammalian cells in culture by (+) and (-) trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrenes and the hydrolysis and reduction products of two stereoisomeric benzo(a)pyrene 7,8-diol-9,10-epoxides.
    Huberman E, Yang SK, McCourt DW, Gelboin HV.
    Cancer Lett; 1978 Jan 25; 4(1):35-43. PubMed ID: 624112
    [Abstract] [Full Text] [Related]

  • 14. Tumorigenicity studies with diol-epoxides of benzo(a)pyrene which indicate that (+/-)-trans-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene is an ultimate carcinogen in newborn mice.
    Kapitulnik J, Wislocki PG, Levin W, Yagi H, Jerina DM, Conney AH.
    Cancer Res; 1978 Feb 25; 38(2):354-8. PubMed ID: 620406
    [Abstract] [Full Text] [Related]

  • 15. Enzymatic conversion of benzo(a)pyrene leading predominantly to the diol-epoxide r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene through a single enantiomer of r-7, t-8-dihydroxy-7,8-dihydrobenzo(a)pyrene.
    Yang SK, McCourt DW, Roller PP, Gelboin HV.
    Proc Natl Acad Sci U S A; 1976 Aug 25; 73(8):2594-8. PubMed ID: 1066669
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids.
    Huang MT, Wood AW, Newmark HL, Sayer JM, Yagi H, Jerina DM, Conney AH.
    Carcinogenesis; 1983 Dec 25; 4(12):1631-7. PubMed ID: 6360409
    [Abstract] [Full Text] [Related]

  • 17. Relationship between benzo(a)pyrene-induced DNA base modification and frequency of reverse mutations in mutant strains of Salmonella typhimurium.
    Fahl WE, Scarpelli DG, Gill K.
    Cancer Res; 1981 Sep 25; 41(9 Pt 1):3400-6. PubMed ID: 6266655
    [Abstract] [Full Text] [Related]

  • 18. Repair of DNA damaged by mutagenic metabolites of benzo(a)pyrene in human cells.
    Regan JD, Francis AA, Dunn WC, Hernandez O, Yagi H, Jerina DM.
    Chem Biol Interact; 1978 Mar 25; 20(3):279-87. PubMed ID: 657391
    [Abstract] [Full Text] [Related]

  • 19. Metabolic activation to a mutagen of 3-hydroxy-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene, a secondary metabolite of benzo[a]pyrene.
    Glatt H, Seidel A, Ribeiro O, Kirkby C, Hirom P, Oesch F.
    Carcinogenesis; 1987 Nov 25; 8(11):1621-7. PubMed ID: 3311446
    [Abstract] [Full Text] [Related]

  • 20. Comparison of the tumor-initiating activities of benzo(a)pyrene arene oxides and diol-epoxides.
    Slaga TJ, Bracken WM, Viaje A, Levin W, Yagi H, Jerina DM, Conney AH.
    Cancer Res; 1977 Nov 25; 37(11):4130-3. PubMed ID: 908047
    [Abstract] [Full Text] [Related]


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