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142 related items for PubMed ID: 10612585

  • 1. Synthesis and acetylcholinesterase inhibitory activity of huperzine A-E2020 combined compound.
    Zeng F, Jiang H, Zhai Y, Zhang H, Chen K, Ji R.
    Bioorg Med Chem Lett; 1999 Dec 06; 9(23):3279-84. PubMed ID: 10612585
    [Abstract] [Full Text] [Related]

  • 2. Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs.
    Kryger G, Silman I, Sussman JL.
    Structure; 1999 Mar 15; 7(3):297-307. PubMed ID: 10368299
    [Abstract] [Full Text] [Related]

  • 3. Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities.
    Cheng DH, Tang XC.
    Pharmacol Biochem Behav; 1998 Jun 15; 60(2):377-86. PubMed ID: 9632220
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and evaluation of tacrine-E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Shao D, Zou C, Luo C, Tang X, Li Y.
    Bioorg Med Chem Lett; 2004 Sep 20; 14(18):4639-42. PubMed ID: 15324879
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors.
    Hu Y, Zhang J, Chandrashankra O, Ip FC, Ip NY.
    Bioorg Med Chem; 2013 Feb 01; 21(3):676-83. PubMed ID: 23273608
    [Abstract] [Full Text] [Related]

  • 6. The rationale for E2020 as a potent acetylcholinesterase inhibitor.
    Kawakami Y, Inoue A, Kawai T, Wakita M, Sugimoto H, Hopfinger AJ.
    Bioorg Med Chem; 1996 Sep 01; 4(9):1429-46. PubMed ID: 8894101
    [Abstract] [Full Text] [Related]

  • 7. Prediction of the binding site of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine in acetylcholinesterase by docking studies with the SYSDOC program.
    Pang YP, Kozikowski AP.
    J Comput Aided Mol Des; 1994 Dec 01; 8(6):683-93. PubMed ID: 7738604
    [Abstract] [Full Text] [Related]

  • 8. Anticholinesterase effects of huperzine A, E2020, and tacrine in rats.
    Wang H, Tang XC.
    Zhongguo Yao Li Xue Bao; 1998 Jan 01; 19(1):27-30. PubMed ID: 10375753
    [Abstract] [Full Text] [Related]

  • 9. Huperzine A, a novel promising acetylcholinesterase inhibitor.
    Cheng DH, Ren H, Tang XC.
    Neuroreport; 1996 Dec 20; 8(1):97-101. PubMed ID: 9051760
    [Abstract] [Full Text] [Related]

  • 10. Quaternary salts of E2020 analogues as acetylcholinesterase inhibitors for the reversal of neuromuscular block.
    Clark JK, Cowley P, Muir AW, Palin R, Pow E, Prosser AB, Taylor R, Zhang MQ.
    Bioorg Med Chem Lett; 2002 Sep 16; 12(18):2565-8. PubMed ID: 12182861
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS, Zhang T, Liu Y, Yang J, Xie SS, Liu J, Miao ZY, Ding Y.
    Eur J Med Chem; 2017 Jun 16; 133():184-196. PubMed ID: 28388521
    [Abstract] [Full Text] [Related]

  • 12. Donepezil hydrochloride: a treatment drug for Alzheimer's disease.
    Sugimoto H.
    Chem Rec; 2001 Jun 16; 1(1):63-73. PubMed ID: 11893059
    [Abstract] [Full Text] [Related]

  • 13. Molecular modelling and QSAR of reversible acetylcholines-terase inhibitors.
    Kaur J, Zhang MQ.
    Curr Med Chem; 2000 Mar 16; 7(3):273-94. PubMed ID: 10637365
    [Abstract] [Full Text] [Related]

  • 14. Dynamic mechanism of E2020 binding to acetylcholinesterase: a steered molecular dynamics simulation.
    Niu C, Xu Y, Xu Y, Luo X, Duan W, Silman I, Sussman JL, Zhu W, Chen K, Shen J, Jiang H.
    J Phys Chem B; 2005 Dec 15; 109(49):23730-8. PubMed ID: 16375354
    [Abstract] [Full Text] [Related]

  • 15. Three-dimensional structure of a complex of E2020 with acetylcholinesterase from Torpedo californica.
    Kryger G, Silman I, Sussman JL.
    J Physiol Paris; 1998 Dec 15; 92(3-4):191-4. PubMed ID: 9789806
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil.
    Omran Z, Cailly T, Lescot E, Santos JS, Agondanou JH, Lisowski V, Fabis F, Godard AM, Stiebing S, Le Flem G, Boulouard M, Dauphin F, Dallemagne P, Rault S.
    Eur J Med Chem; 2005 Dec 15; 40(12):1222-45. PubMed ID: 16137794
    [Abstract] [Full Text] [Related]

  • 17. Kinetic study on the inhibition of acetylcholinesterase by 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride (E2020).
    Nochi S, Asakawa N, Sato T.
    Biol Pharm Bull; 1995 Aug 15; 18(8):1145-7. PubMed ID: 8535413
    [Abstract] [Full Text] [Related]

  • 18. Donepezil hydrochloride (E2020) and other acetylcholinesterase inhibitors.
    Sugimoto H, Yamanishi Y, Iimura Y, Kawakami Y.
    Curr Med Chem; 2000 Mar 15; 7(3):303-39. PubMed ID: 10637367
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
    Dias Viegas FP, de Freitas Silva M, Divino da Rocha M, Castelli MR, Riquiel MM, Machado RP, Vaz SM, Simões de Lima LM, Mancini KC, Marques de Oliveira PC, Morais ÉP, Gontijo VS, da Silva FMR, D'Alincourt da Fonseca Peçanha D, Castro NG, Neves GA, Giusti-Paiva A, Vilela FC, Orlandi L, Camps I, Veloso MP, Leomil Coelho LF, Ionta M, Ferreira-Silva GÁ, Pereira RM, Dardenne LE, Guedes IA, de Oliveira Carneiro Junior W, Quaglio Bellozi PM, Pinheiro de Oliveira AC, Ferreira FF, Pruccoli L, Tarozzi A, Viegas C.
    Eur J Med Chem; 2018 Mar 10; 147():48-65. PubMed ID: 29421570
    [Abstract] [Full Text] [Related]

  • 20. Comparative studies of huperzine A, donepezil, and rivastigmine on brain acetylcholine, dopamine, norepinephrine, and 5-hydroxytryptamine levels in freely-moving rats.
    Liang YQ, Tang XC.
    Acta Pharmacol Sin; 2006 Sep 10; 27(9):1127-36. PubMed ID: 16923332
    [Abstract] [Full Text] [Related]

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