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218 related items for PubMed ID: 10625457

  • 1. Deconstruction of the catalytic array within the amidotransferase subunit of carbamoyl phosphate synthetase.
    Huang X, Raushel FM.
    Biochemistry; 1999 Nov 30; 38(48):15909-14. PubMed ID: 10625457
    [Abstract] [Full Text] [Related]

  • 2. The catalytic mechanism of the amidotransferase domain of the Syrian hamster multifunctional protein CAD. Evidence for a CAD-glutamyl covalent intermediate in the formation of carbamyl phosphate.
    Chaparian MG, Evans DR.
    J Biol Chem; 1991 Feb 25; 266(6):3387-95. PubMed ID: 1671673
    [Abstract] [Full Text] [Related]

  • 3. Role of the hinge loop linking the N- and C-terminal domains of the amidotransferase subunit of carbamoyl phosphate synthetase.
    Huang X, Raushel FM.
    Arch Biochem Biophys; 2000 Aug 01; 380(1):174-80. PubMed ID: 10900147
    [Abstract] [Full Text] [Related]

  • 4. An engineered blockage within the ammonia tunnel of carbamoyl phosphate synthetase prevents the use of glutamine as a substrate but not ammonia.
    Huang X, Raushel FM.
    Biochemistry; 2000 Mar 28; 39(12):3240-7. PubMed ID: 10727215
    [Abstract] [Full Text] [Related]

  • 5. Functional linkage between the glutaminase and synthetase domains of carbamoyl-phosphate synthetase. Role of serine 44 in carbamoyl-phosphate synthetase-aspartate carbamoyltransferase-dihydroorotase (cad).
    Hewagama A, Guy HI, Vickrey JF, Evans DR.
    J Biol Chem; 1999 Oct 01; 274(40):28240-5. PubMed ID: 10497179
    [Abstract] [Full Text] [Related]

  • 6. Regulatory control of the amidotransferase domain of carbamoyl phosphate synthetase.
    Miles BW, Banzon JA, Raushel FM.
    Biochemistry; 1998 Nov 24; 37(47):16773-9. PubMed ID: 9843448
    [Abstract] [Full Text] [Related]

  • 7. Role of the four conserved histidine residues in the amidotransferase domain of carbamoyl phosphate synthetase.
    Miran SG, Chang SH, Raushel FM.
    Biochemistry; 1991 Aug 13; 30(32):7901-7. PubMed ID: 1868065
    [Abstract] [Full Text] [Related]

  • 8. Carbamoyl phosphate synthetase: caught in the act of glutamine hydrolysis.
    Thoden JB, Miran SG, Phillips JC, Howard AJ, Raushel FM, Holden HM.
    Biochemistry; 1998 Jun 23; 37(25):8825-31. PubMed ID: 9636022
    [Abstract] [Full Text] [Related]

  • 9. Role of conserved residues within the carboxy phosphate domain of carbamoyl phosphate synthetase.
    Stapleton MA, Javid-Majd F, Harmon MF, Hanks BA, Grahmann JL, Mullins LS, Raushel FM.
    Biochemistry; 1996 Nov 12; 35(45):14352-61. PubMed ID: 8916922
    [Abstract] [Full Text] [Related]

  • 10. Long-range allosteric transitions in carbamoyl phosphate synthetase.
    Thoden JB, Huang X, Kim J, Raushel FM, Holden HM.
    Protein Sci; 2004 Sep 12; 13(9):2398-405. PubMed ID: 15322282
    [Abstract] [Full Text] [Related]

  • 11. Mutational analysis of carbamyl phosphate synthetase. Substitution of Glu841 leads to loss of functional coupling between the two catalytic domains of the synthetase subunit.
    Guillou F, Liao M, Garcia-Espana A, Lusty CJ.
    Biochemistry; 1992 Feb 18; 31(6):1656-64. PubMed ID: 1737023
    [Abstract] [Full Text] [Related]

  • 12. Carbamoyl phosphate synthetase: a crooked path from substrates to products.
    Raushel FM, Thoden JB, Reinhart GD, Holden HM.
    Curr Opin Chem Biol; 1998 Oct 18; 2(5):624-32. PubMed ID: 9818189
    [Abstract] [Full Text] [Related]

  • 13. Differential roles for three conserved histidine residues within the large subunit of carbamoyl phosphate synthetase.
    Miles BW, Mareya SM, Post LE, Post DJ, Chang SH, Raushel FM.
    Biochemistry; 1993 Jan 12; 32(1):232-40. PubMed ID: 8418843
    [Abstract] [Full Text] [Related]

  • 14. The function of Glu338 in the catalytic triad of the carbamoyl phosphate synthetase amidotransferase domain.
    Hewagama A, Guy HI, Chaparian M, Evans DR.
    Biochim Biophys Acta; 1998 Nov 10; 1388(2):489-99. PubMed ID: 9858783
    [Abstract] [Full Text] [Related]

  • 15. Regulatory changes in the control of carbamoyl phosphate synthetase induced by truncation and mutagenesis of the allosteric binding domain.
    Czerwinski RM, Mareya SM, Raushel FM.
    Biochemistry; 1995 Oct 24; 34(42):13920-7. PubMed ID: 7577987
    [Abstract] [Full Text] [Related]

  • 16. Substitution of Glu841 by lysine in the carbamate domain of carbamyl phosphate synthetase alters the catalytic properties of the glutaminase subunit.
    Lusty CJ, Liao M.
    Biochemistry; 1993 Feb 09; 32(5):1278-84. PubMed ID: 8095404
    [Abstract] [Full Text] [Related]

  • 17. The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
    Thoden JB, Huang X, Raushel FM, Holden HM.
    Biochemistry; 1999 Dec 07; 38(49):16158-66. PubMed ID: 10587438
    [Abstract] [Full Text] [Related]

  • 18. Mechanism of carbamoyl phosphate synthetase from Escherichia coli--binding of the ATP molecules used in the reaction and sequestration by the enzyme of the ATP molecule that yields carbamoyl phosphate.
    Rubio V, Llorente P, Britton HG.
    Eur J Biochem; 1998 Jul 01; 255(1):262-70. PubMed ID: 9692927
    [Abstract] [Full Text] [Related]

  • 19. Structural defects within the carbamate tunnel of carbamoyl phosphate synthetase.
    Kim J, Howell S, Huang X, Raushel FM.
    Biochemistry; 2002 Oct 22; 41(42):12575-81. PubMed ID: 12379099
    [Abstract] [Full Text] [Related]

  • 20. Mutagenesis and mechanism-based inhibition of Streptococcus pyogenes Glu-tRNAGln amidotransferase implicate a serine-based glutaminase site.
    Harpel MR, Horiuchi KY, Luo Y, Shen L, Jiang W, Nelson DJ, Rogers KC, Decicco CP, Copeland RA.
    Biochemistry; 2002 May 21; 41(20):6398-407. PubMed ID: 12009902
    [Abstract] [Full Text] [Related]

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