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Journal Abstract Search

377 related items for PubMed ID: 10630188

  • 1. ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis.
    Kruman II, Pedersen WA, Springer JE, Mattson MP.
    Exp Neurol; 1999 Nov; 160(1):28-39. PubMed ID: 10630188
    [Abstract] [Full Text] [Related]

  • 2. N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.
    Urushitani M, Nakamizo T, Inoue R, Sawada H, Kihara T, Honda K, Akaike A, Shimohama S.
    J Neurosci Res; 2001 Mar 01; 63(5):377-87. PubMed ID: 11223912
    [Abstract] [Full Text] [Related]

  • 3. Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.
    Brunet N, Tarabal O, Esquerda JE, Calderó J.
    J Comp Neurol; 2009 Oct 01; 516(4):277-90. PubMed ID: 19634179
    [Abstract] [Full Text] [Related]

  • 4. ALS-linked Cu/Zn-SOD mutation impairs cerebral synaptic glucose and glutamate transport and exacerbates ischemic brain injury.
    Guo Z, Kindy MS, Kruman I, Mattson MP.
    J Cereb Blood Flow Metab; 2000 Mar 01; 20(3):463-8. PubMed ID: 10724110
    [Abstract] [Full Text] [Related]

  • 5. AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo.
    Corona JC, Tapia R.
    J Neurochem; 2004 May 01; 89(4):988-97. PubMed ID: 15140197
    [Abstract] [Full Text] [Related]

  • 6. Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis.
    Cutler RG, Pedersen WA, Camandola S, Rothstein JD, Mattson MP.
    Ann Neurol; 2002 Oct 01; 52(4):448-57. PubMed ID: 12325074
    [Abstract] [Full Text] [Related]

  • 7. Impairment of nuclear factor-kappaB activation increased glutamate excitotoxicity in a motoneuron-neuroblastoma hybrid cell line expressing mutant (G93A) Cu/Zn-superoxide dismutase.
    Pyo JS, Ko YS, Kim WH, Kim M, Lee KW, Nam SY, Chung HY, Cho SJ, Baik TK, Lee BL.
    J Neurosci Res; 2010 Aug 15; 88(11):2494-503. PubMed ID: 20623531
    [Abstract] [Full Text] [Related]

  • 8. Early signs of motoneuron vulnerability in a disease model system: Characterization of transverse slice cultures of spinal cord isolated from embryonic ALS mice.
    Avossa D, Grandolfo M, Mazzarol F, Zatta M, Ballerini L.
    Neuroscience; 2006 Aug 15; 138(4):1179-94. PubMed ID: 16442737
    [Abstract] [Full Text] [Related]

  • 9. Light and electron microscopic distribution of the AMPA receptor subunit, GluR2, in the spinal cord of control and G86R mutant superoxide dismutase transgenic mice.
    Morrison BM, Janssen WG, Gordon JW, Morrison JH.
    J Comp Neurol; 1998 Jun 15; 395(4):523-34. PubMed ID: 9619504
    [Abstract] [Full Text] [Related]

  • 10. Calcium mediated excitotoxicity in neurofilament aggregate-bearing neurons in vitro is NMDA receptor dependant.
    Sanelli T, Ge W, Leystra-Lantz C, Strong MJ.
    J Neurol Sci; 2007 May 15; 256(1-2):39-51. PubMed ID: 17368487
    [Abstract] [Full Text] [Related]

  • 11. Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity.
    Pérez MJ, Cederbaum AI.
    Hepatology; 2003 Nov 15; 38(5):1146-58. PubMed ID: 14578853
    [Abstract] [Full Text] [Related]

  • 12. Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms.
    Roy J, Minotti S, Dong L, Figlewicz DA, Durham HD.
    J Neurosci; 1998 Dec 01; 18(23):9673-84. PubMed ID: 9822728
    [Abstract] [Full Text] [Related]

  • 13. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury.
    Reaume AG, Elliott JL, Hoffman EK, Kowall NW, Ferrante RJ, Siwek DF, Wilcox HM, Flood DG, Beal MF, Brown RH, Scott RW, Snider WD.
    Nat Genet; 1996 May 01; 13(1):43-7. PubMed ID: 8673102
    [Abstract] [Full Text] [Related]

  • 14. Identification of three mutations in the Cu,Zn-superoxide dismutase (Cu,Zn-SOD) gene with familial amyotrophic lateral sclerosis: transduction of human Cu,Zn-SOD into PC12 cells by HIV-1 TAT protein basic domain.
    Chou CM, Huang CJ, Shih CM, Chen YP, Liu TP, Chen CT.
    Ann N Y Acad Sci; 2005 May 01; 1042():303-13. PubMed ID: 15965076
    [Abstract] [Full Text] [Related]

  • 15. Protective effect of parvalbumin on excitotoxic motor neuron death.
    Van Den Bosch L, Schwaller B, Vleminckx V, Meijers B, Stork S, Ruehlicke T, Van Houtte E, Klaassen H, Celio MR, Missiaen L, Robberecht W, Berchtold MW.
    Exp Neurol; 2002 Apr 01; 174(2):150-61. PubMed ID: 11922657
    [Abstract] [Full Text] [Related]

  • 16. Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity.
    Van Damme P, Bogaert E, Dewil M, Hersmus N, Kiraly D, Scheveneels W, Bockx I, Braeken D, Verpoorten N, Verhoeven K, Timmerman V, Herijgers P, Callewaert G, Carmeliet P, Van Den Bosch L, Robberecht W.
    Proc Natl Acad Sci U S A; 2007 Sep 11; 104(37):14825-30. PubMed ID: 17804792
    [Abstract] [Full Text] [Related]

  • 17. Effects of mitochondrial dysfunction on glutamate receptor-mediated neurotoxicity in cultured rat spinal motor neurons.
    Kanki R, Nakamizo T, Yamashita H, Kihara T, Sawada H, Uemura K, Kawamata J, Shibasaki H, Akaike A, Shimohama S.
    Brain Res; 2004 Jul 23; 1015(1-2):73-81. PubMed ID: 15223368
    [Abstract] [Full Text] [Related]

  • 18. Overexpression of metallothionein protects cultured motor neurons against oxidative stress, but not mutant Cu/Zn-superoxide dismutase toxicity.
    Taylor DM, Minotti S, Agar JN, Durham HD.
    Neurotoxicology; 2004 Sep 23; 25(5):779-92. PubMed ID: 15288509
    [Abstract] [Full Text] [Related]

  • 19. Differing effects of copper,zinc superoxide dismutase overexpression on neurotoxicity elicited by nitric oxide, reactive oxygen species, and excitotoxins.
    Ying W, Anderson CM, Chen Y, Stein BA, Fahlman CS, Copin JC, Chan PH, Swanson RA.
    J Cereb Blood Flow Metab; 2000 Feb 23; 20(2):359-68. PubMed ID: 10698074
    [Abstract] [Full Text] [Related]

  • 20. Ca2+-permeable AMPA receptors and intracellular Ca2+ determine motoneuron vulnerability in rat spinal cord in vivo.
    Corona JC, Tapia R.
    Neuropharmacology; 2007 Apr 23; 52(5):1219-28. PubMed ID: 17320918
    [Abstract] [Full Text] [Related]

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