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Journal Abstract Search

470 related items for PubMed ID: 10644715

  • 1.
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  • 2. Protein kinase C regulation of intracellular and cell surface amyloid precursor protein (APP) cleavage in CHO695 cells.
    Jolly-Tornetta C, Wolf BA.
    Biochemistry; 2000 Dec 12; 39(49):15282-90. PubMed ID: 11106509
    [Abstract] [Full Text] [Related]

  • 3. Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease.
    Lammich S, Kojro E, Postina R, Gilbert S, Pfeiffer R, Jasionowski M, Haass C, Fahrenholz F.
    Proc Natl Acad Sci U S A; 1999 Mar 30; 96(7):3922-7. PubMed ID: 10097139
    [Abstract] [Full Text] [Related]

  • 4. A distinct ER/IC gamma-secretase competes with the proteasome for cleavage of APP.
    Skovronsky DM, Pijak DS, Doms RW, Lee VM.
    Biochemistry; 2000 Feb 01; 39(4):810-7. PubMed ID: 10651647
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  • 5. The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells.
    Kuentzel SL, Ali SM, Altman RA, Greenberg BD, Raub TJ.
    Biochem J; 1993 Oct 15; 295 ( Pt 2)(Pt 2):367-78. PubMed ID: 8240235
    [Abstract] [Full Text] [Related]

  • 6. The trans-Golgi network is a major site for α-secretase processing of amyloid precursor protein in primary neurons.
    Tan JZA, Gleeson PA.
    J Biol Chem; 2019 Feb 01; 294(5):1618-1631. PubMed ID: 30545942
    [Abstract] [Full Text] [Related]

  • 7. Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.
    Parvathy S, Hussain I, Karran EH, Turner AJ, Hooper NM.
    Biochemistry; 1999 Jul 27; 38(30):9728-34. PubMed ID: 10423252
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  • 10. Effects of TNFalpha-converting enzyme inhibition on amyloid beta production and APP processing in vitro and in vivo.
    Kim ML, Zhang B, Mills IP, Milla ME, Brunden KR, Lee VM.
    J Neurosci; 2008 Nov 12; 28(46):12052-61. PubMed ID: 19005070
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.
    Thinakaran G, Teplow DB, Siman R, Greenberg B, Sisodia SS.
    J Biol Chem; 1996 Apr 19; 271(16):9390-7. PubMed ID: 8621605
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  • 12. Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding.
    Parvathy S, Ehrlich M, Pedrini S, Diaz N, Refolo L, Buxbaum JD, Bogush A, Petanceska S, Gandy S.
    J Neurochem; 2004 Aug 19; 90(4):1005-10. PubMed ID: 15287907
    [Abstract] [Full Text] [Related]

  • 13. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W.
    Eur J Neurosci; 2013 Jun 19; 37(12):1962-9. PubMed ID: 23773065
    [Abstract] [Full Text] [Related]

  • 14. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
    Gandhi S, Refolo LM, Sambamurti K.
    J Mol Neurosci; 2004 Jun 19; 24(1):137-43. PubMed ID: 15314262
    [Abstract] [Full Text] [Related]

  • 15. Novel alpha-secretase cleavage of Alzheimer's amyloid beta precursor protein in the endoplasmic reticulum of COS7 cells.
    Shin RW, Saido TC, Maeda M, Kitamoto T.
    Neurosci Lett; 2005 Mar 07; 376(1):14-9. PubMed ID: 15694266
    [Abstract] [Full Text] [Related]

  • 16. Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein.
    Sambamurti K, Sevlever D, Koothan T, Refolo LM, Pinnix I, Gandhi S, Onstead L, Younkin L, Prada CM, Yager D, Ohyagi Y, Eckman CB, Rosenberry TL, Younkin SG.
    J Biol Chem; 1999 Sep 17; 274(38):26810-4. PubMed ID: 10480887
    [Abstract] [Full Text] [Related]

  • 17. Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10.
    Lopez-Perez E, Zhang Y, Frank SJ, Creemers J, Seidah N, Checler F.
    J Neurochem; 2001 Mar 17; 76(5):1532-9. PubMed ID: 11238737
    [Abstract] [Full Text] [Related]

  • 18. Regulation of APP cleavage by alpha-, beta- and gamma-secretases.
    Nunan J, Small DH.
    FEBS Lett; 2000 Oct 13; 483(1):6-10. PubMed ID: 11033346
    [Abstract] [Full Text] [Related]

  • 19. Metabolites of the beta-amyloid precursor protein generated by beta-secretase localise to the trans-Golgi network and late endosome in 293 cells.
    Stephens DJ, Austen BM.
    J Neurosci Res; 1996 Oct 15; 46(2):211-25. PubMed ID: 8915898
    [Abstract] [Full Text] [Related]

  • 20. Role of the APP non-amyloidogenic signaling pathway and targeting alpha-secretase as an alternative drug target for treatment of Alzheimer's disease.
    Bandyopadhyay S, Goldstein LE, Lahiri DK, Rogers JT.
    Curr Med Chem; 2007 Oct 15; 14(27):2848-64. PubMed ID: 18045131
    [Abstract] [Full Text] [Related]

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