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920 related items for PubMed ID: 10646524

  • 1. Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.
    Vila M, Vukosavic S, Jackson-Lewis V, Neystat M, Jakowec M, Przedborski S.
    J Neurochem; 2000 Feb; 74(2):721-9. PubMed ID: 10646524
    [Abstract] [Full Text] [Related]

  • 2. Overexpression of Parkinson's disease-associated alpha-synucleinA53T by recombinant adeno-associated virus in mice does not increase the vulnerability of dopaminergic neurons to MPTP.
    Dong Z, Ferger B, Feldon J, Büeler H.
    J Neurobiol; 2002 Oct; 53(1):1-10. PubMed ID: 12360578
    [Abstract] [Full Text] [Related]

  • 3. The mouse MPTP model: gene expression changes in dopaminergic neurons.
    Kühn K, Wellen J, Link N, Maskri L, Lübbert H, Stichel CC.
    Eur J Neurosci; 2003 Jan; 17(1):1-12. PubMed ID: 12534964
    [Abstract] [Full Text] [Related]

  • 4. Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration.
    Drolet RE, Behrouz B, Lookingland KJ, Goudreau JL.
    Neurotoxicology; 2004 Sep; 25(5):761-9. PubMed ID: 15288507
    [Abstract] [Full Text] [Related]

  • 5. Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice.
    Robertson DC, Schmidt O, Ninkina N, Jones PA, Sharkey J, Buchman VL.
    J Neurochem; 2004 Jun; 89(5):1126-36. PubMed ID: 15147505
    [Abstract] [Full Text] [Related]

  • 6. Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
    Schlüter OM, Fornai F, Alessandrí MG, Takamori S, Geppert M, Jahn R, Südhof TC.
    Neuroscience; 2003 Jun; 118(4):985-1002. PubMed ID: 12732244
    [Abstract] [Full Text] [Related]

  • 7. Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate.
    Mandel S, Maor G, Youdim MB.
    J Mol Neurosci; 2004 Jun; 24(3):401-16. PubMed ID: 15655262
    [Abstract] [Full Text] [Related]

  • 8. MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons.
    Kowall NW, Hantraye P, Brouillet E, Beal MF, McKee AC, Ferrante RJ.
    Neuroreport; 2000 Jan 17; 11(1):211-3. PubMed ID: 10683860
    [Abstract] [Full Text] [Related]

  • 9. Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice.
    Rathke-Hartlieb S, Kahle PJ, Neumann M, Ozmen L, Haid S, Okochi M, Haass C, Schulz JB.
    J Neurochem; 2001 May 17; 77(4):1181-4. PubMed ID: 11359883
    [Abstract] [Full Text] [Related]

  • 10. Selective alterations of gene expression in mice induced by MPTP.
    Xu Z, Cawthon D, McCastlain KA, Slikker W, Ali SF.
    Synapse; 2005 Jan 17; 55(1):45-51. PubMed ID: 15499605
    [Abstract] [Full Text] [Related]

  • 11. Systemically administered neuregulin-1β1 rescues nigral dopaminergic neurons via the ErbB4 receptor tyrosine kinase in MPTP mouse models of Parkinson's disease.
    Depboylu C, Rösler TW, de Andrade A, Oertel WH, Höglinger GU.
    J Neurochem; 2015 May 17; 133(4):590-7. PubMed ID: 25581060
    [Abstract] [Full Text] [Related]

  • 12. What have we learnt from CDNA microarray gene expression studies about the role of iron in MPTP induced neurodegeneration and Parkinson's disease?
    Youdim MB.
    J Neural Transm Suppl; 2003 May 17; (65):73-88. PubMed ID: 12946050
    [Abstract] [Full Text] [Related]

  • 13. Dose-related biphasic effect of the Parkinson's disease neurotoxin MPTP, on the spread, accumulation, and toxicity of α-synuclein.
    Merghani MM, Ardah MT, Al Shamsi M, Kitada T, Haque ME.
    Neurotoxicology; 2021 May 17; 84():41-52. PubMed ID: 33549656
    [Abstract] [Full Text] [Related]

  • 14. Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.
    Song DD, Shults CW, Sisk A, Rockenstein E, Masliah E.
    Exp Neurol; 2004 Apr 17; 186(2):158-72. PubMed ID: 15026254
    [Abstract] [Full Text] [Related]

  • 15. Regulation of alpha-synuclein by bFGF in cultured ventral midbrain dopaminergic neurons.
    Rideout HJ, Dietrich P, Savalle M, Dauer WT, Stefanis L.
    J Neurochem; 2003 Feb 17; 84(4):803-13. PubMed ID: 12562524
    [Abstract] [Full Text] [Related]

  • 16. Ginsenoside Rg1 attenuates motor impairment and neuroinflammation in the MPTP-probenecid-induced parkinsonism mouse model by targeting α-synuclein abnormalities in the substantia nigra.
    Heng Y, Zhang QS, Mu Z, Hu JF, Yuan YH, Chen NH.
    Toxicol Lett; 2016 Jan 22; 243():7-21. PubMed ID: 26723869
    [Abstract] [Full Text] [Related]

  • 17. Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
    L'Episcopo F, Tirolo C, Caniglia S, Testa N, Serra PA, Impagnatiello F, Morale MC, Marchetti B.
    J Neuroinflammation; 2010 Nov 23; 7():83. PubMed ID: 21092260
    [Abstract] [Full Text] [Related]

  • 18. Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.
    Przedborski S, Chen Q, Vila M, Giasson BI, Djaldatti R, Vukosavic S, Souza JM, Jackson-Lewis V, Lee VM, Ischiropoulos H.
    J Neurochem; 2001 Jan 23; 76(2):637-40. PubMed ID: 11208927
    [Abstract] [Full Text] [Related]

  • 19. Role of nuclear transcription factor kappa B (NF-kappaB) for MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine)-induced apoptosis in nigral neurons of mice.
    Aoki E, Yano R, Yokoyama H, Kato H, Araki T.
    Exp Mol Pathol; 2009 Feb 23; 86(1):57-64. PubMed ID: 19027004
    [Abstract] [Full Text] [Related]

  • 20. Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates.
    Purisai MG, McCormack AL, Langston WJ, Johnston LC, Di Monte DA.
    Neurobiol Dis; 2005 Dec 23; 20(3):898-906. PubMed ID: 16006134
    [Abstract] [Full Text] [Related]

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