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222 related items for PubMed ID: 10666292

  • 1. Ebselen induces apoptosis in HepG(2) cells through rapid depletion of intracellular thiols.
    Yang CF, Shen HM, Ong CN.
    Arch Biochem Biophys; 2000 Feb 15; 374(2):142-52. PubMed ID: 10666292
    [Abstract] [Full Text] [Related]

  • 2. Intracellular thiol depletion causes mitochondrial permeability transition in ebselen-induced apoptosis.
    Yang CF, Shen HM, Ong CN.
    Arch Biochem Biophys; 2000 Aug 15; 380(2):319-30. PubMed ID: 10933887
    [Abstract] [Full Text] [Related]

  • 3. Ebselen augments its peroxidase activity by inducing nrf-2-dependent transcription.
    Tamasi V, Jeffries JM, Arteel GE, Falkner KC.
    Arch Biochem Biophys; 2004 Nov 15; 431(2):161-8. PubMed ID: 15488464
    [Abstract] [Full Text] [Related]

  • 4. Ebselen has dehydroascorbate reductase and thioltransferase-like activities.
    Jung CH, Washburn MP, Wells WW.
    Biochem Biophys Res Commun; 2002 Mar 01; 291(3):550-3. PubMed ID: 11855823
    [Abstract] [Full Text] [Related]

  • 5. Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells.
    Zhang S, Ong CN, Shen HM.
    Cancer Lett; 2004 May 28; 208(2):143-53. PubMed ID: 15142672
    [Abstract] [Full Text] [Related]

  • 6. N-acetyl cysteine inhibits human signet ring cell gastric cancer cell line (SJ-89) cell growth by inducing apoptosis and DNA synthesis arrest.
    Li J, Tu HJ, Li J, Dai G, Dai YC, Wu Q, Shi QZ, Cao Q, Li ZJ.
    Eur J Gastroenterol Hepatol; 2007 Sep 28; 19(9):769-74. PubMed ID: 17700262
    [Abstract] [Full Text] [Related]

  • 7. Prevention of dopamine-induced cell death by thiol antioxidants: possible implications for treatment of Parkinson's disease.
    Offen D, Ziv I, Sternin H, Melamed E, Hochman A.
    Exp Neurol; 1996 Sep 28; 141(1):32-9. PubMed ID: 8797665
    [Abstract] [Full Text] [Related]

  • 8. Effects of preconditioning with ebselen on glutathione metabolism and stress protein expression.
    Hoshida S, Aoki K, Nishida M, Yamashita N, Igarashi J, Hori M, Kuzuya T, Tada M.
    J Pharmacol Exp Ther; 1997 Jun 28; 281(3):1471-5. PubMed ID: 9190885
    [Abstract] [Full Text] [Related]

  • 9. Adult T cell leukemia (ATL)-derived factor/human thioredoxin prevents apoptosis of lymphoid cells induced by L-cystine and glutathione depletion: possible involvement of thiol-mediated redox regulation in apoptosis caused by pro-oxidant state.
    Iwata S, Hori T, Sato N, Hirota K, Sasada T, Mitsui A, Hirakawa T, Yodoi J.
    J Immunol; 1997 Apr 01; 158(7):3108-17. PubMed ID: 9120263
    [Abstract] [Full Text] [Related]

  • 10. Thiol-mediated redox regulation of apoptosis. Possible roles of cellular thiols other than glutathione in T cell apoptosis.
    Sato N, Iwata S, Nakamura K, Hori T, Mori K, Yodoi J.
    J Immunol; 1995 Apr 01; 154(7):3194-203. PubMed ID: 7897207
    [Abstract] [Full Text] [Related]

  • 11. Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats.
    Saad SY, Najjar TA, Arafah MM.
    Basic Clin Pharmacol Toxicol; 2006 Dec 01; 99(6):412-7. PubMed ID: 17169121
    [Abstract] [Full Text] [Related]

  • 12. Ebselen, a seleno-organic antioxidant, as an electrophile.
    Sakurai T, Kanayama M, Shibata T, Itoh K, Kobayashi A, Yamamoto M, Uchida K.
    Chem Res Toxicol; 2006 Sep 01; 19(9):1196-204. PubMed ID: 16978024
    [Abstract] [Full Text] [Related]

  • 13. Effect of glutathione depletion on apoptosis induced by thiram in Chinese hamster fibroblasts.
    Grosicka E, Sadurska B, Szumiło M, Grzela T, Łazarczyk P, Niderla-Bielińska J, Rahden-Staroń I.
    Int Immunopharmacol; 2005 Dec 01; 5(13-14):1945-56. PubMed ID: 16275629
    [Abstract] [Full Text] [Related]

  • 14. Depletion of intracellular glutathione mediates butenolide-induced cytotoxicity in HepG2 cells.
    Wang YM, Peng SQ, Zhou Q, Wang MW, Yan CH, Yang HY, Wang GQ.
    Toxicol Lett; 2006 Jul 14; 164(3):231-8. PubMed ID: 16495022
    [Abstract] [Full Text] [Related]

  • 15. Ebselen attenuates cisplatin-induced ROS generation through Nrf2 activation in auditory cells.
    Kim SJ, Park C, Han AL, Youn MJ, Lee JH, Kim Y, Kim ES, Kim HJ, Kim JK, Lee HK, Chung SY, So H, Park R.
    Hear Res; 2009 May 14; 251(1-2):70-82. PubMed ID: 19286452
    [Abstract] [Full Text] [Related]

  • 16. Ebselen, a redox regulator containing a selenium atom, induces neurofilament M expression in cultured rat pheochromocytoma PC12 cells via activation of mitogen-activated protein kinase.
    Nishina A, Sekiguchi A, He Y, Koketsu M, Furukawa S.
    J Neurosci Res; 2008 Feb 15; 86(3):720-5. PubMed ID: 17918745
    [Abstract] [Full Text] [Related]

  • 17. Antioxidant and anti-mutagenic effects of ebselen in yeast and in cultured mammalian V79 cells.
    Miorelli ST, Rosa RM, Moura DJ, Rocha JC, Lobo LA, Henriques JA, Saffi J.
    Mutagenesis; 2008 Mar 15; 23(2):93-9. PubMed ID: 18267951
    [Abstract] [Full Text] [Related]

  • 18. Ebselen attenuates oxidative stress in ischemic astrocytes depleted of glutathione. Comparison with glutathione precursors.
    Gabryel B, Małecki A.
    Pharmacol Rep; 2006 Mar 15; 58(3):381-92. PubMed ID: 16845212
    [Abstract] [Full Text] [Related]

  • 19. Redox modulation at the peripheral site alters nociceptive transmission in vivo.
    Meotti FC, Coelho IS, Franco JL, Dafre AL, Rocha JB, Santos AR.
    Clin Exp Pharmacol Physiol; 2009 Mar 15; 36(3):272-7. PubMed ID: 18986332
    [Abstract] [Full Text] [Related]

  • 20. Enhancement of arsenic trioxide-induced apoptosis in renal cell carcinoma cells by L-buthionine sulfoximine.
    Wu XX, Ogawa O, Kakehi Y.
    Int J Oncol; 2004 Jun 15; 24(6):1489-97. PubMed ID: 15138592
    [Abstract] [Full Text] [Related]

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