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PUBMED FOR HANDHELDS

Journal Abstract Search


158 related items for PubMed ID: 10669560

  • 1. A novel, potent, and selective 5-HT(7) antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl) phen ol (SB-269970).
    Lovell PJ, Bromidge SM, Dabbs S, Duckworth DM, Forbes IT, Jennings AJ, King FD, Middlemiss DN, Rahman SK, Saunders DV, Collin LL, Hagan JJ, Riley GJ, Thomas DR.
    J Med Chem; 2000 Feb 10; 43(3):342-5. PubMed ID: 10669560
    [No Abstract] [Full Text] [Related]

  • 2. New selective and potent 5-HT(1B/1D) antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides.
    Liao Y, Böttcher H, Harting J, Greiner H, van Amsterdam C, Cremers T, Sundell S, März J, Rautenberg W, Wikström H.
    J Med Chem; 2000 Feb 10; 43(3):517-25. PubMed ID: 10669578
    [Abstract] [Full Text] [Related]

  • 3. N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonists.
    Tsai Y, Dukat M, Slassi A, MacLean N, Demchyshyn L, Savage JE, Roth BL, Hufesein S, Lee M, Glennon RA.
    Bioorg Med Chem Lett; 2000 Oct 16; 10(20):2295-9. PubMed ID: 11055342
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  • 4. Synthesis and biological evaluation of benzoisothiazole derivatives possessing N,N-dimethylformimidamide group as 5-HT₆ receptor antagonists.
    Yoo E, Hayat F, Rhim H, Park Choo HY.
    Bioorg Med Chem; 2012 Apr 15; 20(8):2707-12. PubMed ID: 22405919
    [Abstract] [Full Text] [Related]

  • 5. Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors.
    Mahé C, Loetscher E, Feuerbach D, Müller W, Seiler MP, Schoeffter P.
    Eur J Pharmacol; 2004 Jul 14; 495(2-3):97-102. PubMed ID: 15249157
    [Abstract] [Full Text] [Related]

  • 6. (R)-3,N-dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl) propyl]benzenesulfonamide: the first selective 5-HT7 receptor antagonist.
    Forbes IT, Dabbs S, Duckworth DM, Jennings AJ, King FD, Lovell PJ, Brown AM, Collin L, Hagan JJ, Middlemiss DN, Riley GJ, Thomas DR, Upton N.
    J Med Chem; 1998 Feb 26; 41(5):655-7. PubMed ID: 9513592
    [No Abstract] [Full Text] [Related]

  • 7. N,N-Dimethyl-[9-(arylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]amines as novel, potent and selective 5-HT₆ receptor antagonists.
    Nirogi RV, Konda JB, Kambhampati R, Shinde A, Bandyala TR, Gudla P, Kandukuri KK, Jayarajan P, Kandikere V, Dubey PK.
    Bioorg Med Chem Lett; 2012 Nov 15; 22(22):6980-5. PubMed ID: 23036955
    [Abstract] [Full Text] [Related]

  • 8. Bicyclic piperazinylbenzenesulphonamides are potent and selective 5-HT6 receptor antagonists.
    Bromidge SM, Clarke SE, King FD, Lovell PJ, Newman H, Riley G, Routledge C, Serafinowska HT, Smith DR, Thomas DR.
    Bioorg Med Chem Lett; 2002 May 20; 12(10):1357-60. PubMed ID: 11992776
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  • 11. 1-Thia-4,7-diaza-spiro[4.4]nonane-3,6-dione: a structural motif for 5-hydroxytryptamine 6 receptor antagonism.
    Hostetler G, Dunn D, McKenna BA, Kopec K, Chatterjee S.
    Chem Biol Drug Des; 2014 Feb 20; 83(2):149-53. PubMed ID: 24119217
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  • 12. N'-(arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor (5-HT₆R) antagonists with unique structural features.
    van Loevezijn A, Venhorst J, Iwema Bakker WI, de Korte CG, de Looff W, Verhoog S, van Wees JW, van Hoeve M, van de Woestijne RP, van der Neut MA, Borst AJ, van Dongen MJ, de Bruin NM, Keizer HG, Kruse CG.
    J Med Chem; 2011 Oct 27; 54(20):7030-54. PubMed ID: 21866910
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  • 14. Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding.
    Metwally KA, Dukat M, Egan CT, Smith C, DuPre A, Gauthier CB, Herrick-Davis K, Teitler M, Glennon RA.
    J Med Chem; 1998 Dec 03; 41(25):5084-93. PubMed ID: 9836624
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  • 16. Synthesis and pharmacological activity of metabolites of the 5-HT(4) receptor antagonist SB-207266.
    Fedouloff M, Hossner F, Voyle M, Ranson J, Powles J, Riley G, Sanger G.
    Bioorg Med Chem; 2001 Aug 03; 9(8):2119-28. PubMed ID: 11504648
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