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PUBMED FOR HANDHELDS

Journal Abstract Search


216 related items for PubMed ID: 10669570

  • 1. Synthesis and in vitro and in vivo functional studies of ortho-substituted phenylpiperazine and N-substituted 4-N-(o-methoxyphenyl)aminopiperidine analogues of WAY100635.
    Mensonides-Harsema MM, Liao Y, Böttcher H, Bartoszyk GD, Greiner HE, Harting J, de Boer P, Wikström HV.
    J Med Chem; 2000 Feb 10; 43(3):432-9. PubMed ID: 10669570
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors.
    Orús L, Pérez-Silanes S, Oficialdegui AM, Martínez-Esparza J, Del Castillo JC, Mourelle M, Langer T, Guccione S, Donzella G, Krovat EM, Poptodorov K, Lasheras B, Ballaz S, Hervías I, Tordera R, Del Río J, Monge A.
    J Med Chem; 2002 Sep 12; 45(19):4128-39. PubMed ID: 12213056
    [Abstract] [Full Text] [Related]

  • 3. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Niso M, Perrone R, Tortorella V.
    J Med Chem; 2004 Dec 16; 47(26):6616-24. PubMed ID: 15588097
    [Abstract] [Full Text] [Related]

  • 4. Active conformation of some arylpiperazine postsynaptic 5-HT(1A) receptor antagonists.
    Paluchowska MH, Bojarski AJ, Charakchieva-Minol S, Wesołowska A.
    Eur J Med Chem; 2002 Apr 16; 37(4):273-83. PubMed ID: 11960662
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and structure-activity relationships of a new model of arylpiperazines. 5. Study of the physicochemical influence of the pharmacophore on 5-HT(1a)/alpha(1)-adrenergic receptor affinity: synthesis of a new derivative with mixed 5-HT(1a)/d(2) antagonist properties.
    López-Rodríguez ML, Morcillo MJ, Fernández E, Porras E, Orensanz L, Beneytez ME, Manzanares J, Fuentes JA.
    J Med Chem; 2001 Jan 18; 44(2):186-97. PubMed ID: 11170628
    [Abstract] [Full Text] [Related]

  • 6. New selective and potent 5-HT(1B/1D) antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides.
    Liao Y, Böttcher H, Harting J, Greiner H, van Amsterdam C, Cremers T, Sundell S, März J, Rautenberg W, Wikström H.
    J Med Chem; 2000 Feb 10; 43(3):517-25. PubMed ID: 10669578
    [Abstract] [Full Text] [Related]

  • 7. The effect of serotonin(1A) receptor agonism on antipsychotic drug-induced dopamine release in rat striatum and nucleus accumbens.
    Ichikawa J, Meltzer HY.
    Brain Res; 2000 Mar 10; 858(2):252-63. PubMed ID: 10708676
    [Abstract] [Full Text] [Related]

  • 8. Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo.
    Lacivita E, Patarnello D, Stroth N, Caroli A, Niso M, Contino M, De Giorgio P, Di Pilato P, Colabufo NA, Berardi F, Perrone R, Svenningsson P, Hedlund PB, Leopoldo M.
    J Med Chem; 2012 Jul 26; 55(14):6375-80. PubMed ID: 22738316
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and pharmacological evaluation of 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-phenylpiperazines with clozapine-like mixed activities at dopamine D(2), serotonin, and GABA(A) receptors.
    Asproni B, Pau A, Bitti M, Melosu M, Cerri R, Dazzi L, Seu E, Maciocco E, Sanna E, Busonero F, Talani G, Pusceddu L, Altomare C, Trapani G, Biggio G.
    J Med Chem; 2002 Oct 10; 45(21):4655-68. PubMed ID: 12361392
    [Abstract] [Full Text] [Related]

  • 10. On the bioactive conformation of NAN-190 (1) and MP3022 (2), 5-HT(1A) receptor antagonists.
    Paluchowska MH, Mokrosz MJ, Bojarski A, Wesołowska A, Borycz J, Charakchieva-Minol S, Chojnacka-Wójcik E.
    J Med Chem; 1999 Dec 02; 42(24):4952-60. PubMed ID: 10585205
    [Abstract] [Full Text] [Related]

  • 11. A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635.
    Forster EA, Cliffe IA, Bill DJ, Dover GM, Jones D, Reilly Y, Fletcher A.
    Eur J Pharmacol; 1995 Jul 25; 281(1):81-8. PubMed ID: 8566121
    [Abstract] [Full Text] [Related]

  • 12. Effect of several 5-hydroxytryptamine(1A) receptor ligands on the micturition reflex in rats: comparison with WAY 100635.
    Testa R, Guarneri L, Poggesi E, Angelico P, Velasco C, Ibba M, Cilia A, Motta G, Riva C, Leonardi A.
    J Pharmacol Exp Ther; 1999 Sep 25; 290(3):1258-69. PubMed ID: 10454502
    [Abstract] [Full Text] [Related]

  • 13. Characterization of 4-(2-hydroxyphenyl)-1-[2'-[N-(2''-pyridinyl)-p-fluorobenzamido]ethyl]piperazine (p-DMPPF) as a new potent 5-HT1A antagonist.
    Defraiteur C, Plenevaux A, Scuvée-Moreau J, Rouchet N, Goblet D, Luxen A, Seutin V.
    Br J Pharmacol; 2007 Nov 25; 152(6):952-8. PubMed ID: 17704821
    [Abstract] [Full Text] [Related]

  • 14. Improvement in the selectivity and metabolic stability of the serotonin 5-HT(1A) ligand, S 15535: a series of cis- and trans-2-(arylcycloalkylamine) 1-indanols.
    Peglion JL, Goument B, Despaux N, Charlot V, Giraud H, Nisole C, Newman-Tancredi A, Dekeyne A, Bertrand M, Genissel P, Millan MJ.
    J Med Chem; 2002 Jan 03; 45(1):165-76. PubMed ID: 11754589
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.
    Perrone R, Berardi F, Colabufo NA, Lacivita E, Leopoldo M, Tortorella V.
    J Med Chem; 2003 Feb 13; 46(4):646-9. PubMed ID: 12570387
    [Abstract] [Full Text] [Related]

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  • 19. In vivo evaluation of 4-[123I]iodo-N-[2[4-(6-trifluoromethyl-2-pyridinyl)-1-piperazinyl]ethyl]benzamide, a potential SPECT radioligand for the 5-HT1A receptor.
    Vandecapelle M, De Vos F, Vermeirsch H, De Ley G, Audenaert K, Leysen D, Dierckx RA, Slegers G.
    Nucl Med Biol; 2001 Aug 13; 28(6):639-43. PubMed ID: 11518645
    [Abstract] [Full Text] [Related]

  • 20. Functional characteristics of a series of N4-substituted 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazines as 5-HT1A receptor ligands. Structure-activity relationships.
    van Steen BJ, van Wijngaarden I, Ronken E, Soudijn W.
    Bioorg Med Chem Lett; 1998 Sep 22; 8(18):2457-62. PubMed ID: 9873561
    [Abstract] [Full Text] [Related]


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