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1085 related items for PubMed ID: 10677285

  • 1. Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent.
    Beiboer SH, Reurs A, Roovers RC, Arends JW, Whitelegg NR, Rees AR, Hoogenboom HR.
    J Mol Biol; 2000 Feb 25; 296(3):833-49. PubMed ID: 10677285
    [Abstract] [Full Text] [Related]

  • 2. Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning.
    Klimka A, Matthey B, Roovers RC, Barth S, Arends JW, Engert A, Hoogenboom HR.
    Br J Cancer; 2000 Jul 25; 83(2):252-60. PubMed ID: 10901379
    [Abstract] [Full Text] [Related]

  • 3. A V kappa-J kappa junctional change in an antidigoxin recombinant antibody destroys digoxin-binding activity.
    Hudson NW, Bruccoleri RE, Steinrauf LK, Hamilton JA, Mudgett-Hunter M, Margolies MN.
    J Immunol; 1990 Oct 15; 145(8):2718-24. PubMed ID: 2120338
    [Abstract] [Full Text] [Related]

  • 4. Human framework adaptation of a mouse anti-human IL-13 antibody.
    Fransson J, Teplyakov A, Raghunathan G, Chi E, Cordier W, Dinh T, Feng Y, Giles-Komar J, Gilliland G, Lollo B, Malia TJ, Nishioka W, Obmolova G, Zhao S, Zhao Y, Swanson RV, Almagro JC.
    J Mol Biol; 2010 Apr 30; 398(2):214-31. PubMed ID: 20226193
    [Abstract] [Full Text] [Related]

  • 5. Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains.
    van den Beucken T, van Neer N, Sablon E, Desmet J, Celis L, Hoogenboom HR, Hufton SE.
    J Mol Biol; 2001 Jul 13; 310(3):591-601. PubMed ID: 11439026
    [Abstract] [Full Text] [Related]

  • 6. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
    Wu H, Nie Y, Huse WD, Watkins JD.
    J Mol Biol; 1999 Nov 19; 294(1):151-62. PubMed ID: 10556035
    [Abstract] [Full Text] [Related]

  • 7. Functional humanization of an anti-CD16 Fab fragment: obstacles of switching from murine {lambda} to human {lambda} or {kappa} light chains.
    Schlapschy M, Fogarasi M, Gruber H, Gresch O, Schäfer C, Aguib Y, Skerra A.
    Protein Eng Des Sel; 2009 Mar 19; 22(3):175-88. PubMed ID: 19022801
    [Abstract] [Full Text] [Related]

  • 8. [Preparation of human Fab antibodies against HAb18G by guided selection and chain shuffling technique].
    Bao GQ, Ma QJ, Xing JL, Yang XM, Chen ZN.
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2004 Jul 19; 20(4):437-40. PubMed ID: 15207089
    [Abstract] [Full Text] [Related]

  • 9. Guided selection of human antibody light chains against TAG-72 using a phage display chain shuffling approach.
    Kim SJ, Hong HJ.
    J Microbiol; 2007 Dec 19; 45(6):572-7. PubMed ID: 18176543
    [Abstract] [Full Text] [Related]

  • 10. Clonal analysis of a human antibody response. III. Nucleotide sequences of monoclonal IgM, IgG, and IgA to rabies virus reveal restricted V kappa gene utilization, junctional V kappa J kappa and V lambda J lambda diversity, and somatic hypermutation.
    Ikematsu W, Kobarg J, Ikematsu H, Ichiyoshi Y, Casali P.
    J Immunol; 1998 Sep 15; 161(6):2895-905. PubMed ID: 9743351
    [Abstract] [Full Text] [Related]

  • 11. Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.
    Finlay WJ, Cunningham O, Lambert MA, Darmanin-Sheehan A, Liu X, Fennell BJ, Mahon CM, Cummins E, Wade JM, O'Sullivan CM, Tan XY, Piche N, Pittman DD, Paulsen J, Tchistiakova L, Kodangattil S, Gill D, Hufton SE.
    J Mol Biol; 2009 May 08; 388(3):541-58. PubMed ID: 19285987
    [Abstract] [Full Text] [Related]

  • 12. [Expression, structure prediction and functional analysis of murine single-chain fragment variable antibody against human cervical cancer].
    Wang Y, Li X, Chen W.
    Nan Fang Yi Ke Da Xue Xue Bao; 2006 Jan 08; 26(1):16-21. PubMed ID: 16495168
    [Abstract] [Full Text] [Related]

  • 13. Anti-estradiol-17beta single-chain Fv fragments: Generation, characterization, gene randomization, and optimized phage display.
    Kobayashi N, Kato Y, Oyama H, Taga S, Niwa T, Sun P, Ohtoyo M, Goto J.
    Steroids; 2008 Dec 22; 73(14):1485-99. PubMed ID: 18824188
    [Abstract] [Full Text] [Related]

  • 14. Humanization and epitope mapping of the H23 anti-MUC1 monoclonal antibody reveals a dual epitope specificity.
    Mazor Y, Keydar I, Benhar I.
    Mol Immunol; 2005 Jan 22; 42(1):55-69. PubMed ID: 15488944
    [Abstract] [Full Text] [Related]

  • 15. Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides.
    Knappik A, Ge L, Honegger A, Pack P, Fischer M, Wellnhofer G, Hoess A, Wölle J, Plückthun A, Virnekäs B.
    J Mol Biol; 2000 Feb 11; 296(1):57-86. PubMed ID: 10656818
    [Abstract] [Full Text] [Related]

  • 16. Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting.
    Villani ME, Morea V, Consalvi V, Chiaraluce R, Desiderio A, Benvenuto E, Donini M.
    Mol Immunol; 2008 May 11; 45(9):2474-85. PubMed ID: 18313757
    [Abstract] [Full Text] [Related]

  • 17. Engineering fully human monoclonal antibodies from murine variable regions.
    Bernett MJ, Karki S, Moore GL, Leung IW, Chen H, Pong E, Nguyen DH, Jacinto J, Zalevsky J, Muchhal US, Desjarlais JR, Lazar GA.
    J Mol Biol; 2010 Mar 12; 396(5):1474-90. PubMed ID: 20045416
    [Abstract] [Full Text] [Related]

  • 18. Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein.
    Pavoni E, Flego M, Dupuis ML, Barca S, Petronzelli F, Anastasi AM, D'Alessio V, Pelliccia A, Vaccaro P, Monteriù G, Ascione A, De Santis R, Felici F, Cianfriglia M, Minenkova O.
    BMC Cancer; 2006 Feb 24; 6():41. PubMed ID: 16504122
    [Abstract] [Full Text] [Related]

  • 19. Generation and selection of immunized Fab phage display library against human B cell lymphoma.
    Shen Y, Yang X, Dong N, Xie X, Bai X, Shi Y.
    Cell Res; 2007 Jul 24; 17(7):650-60. PubMed ID: 17621306
    [Abstract] [Full Text] [Related]

  • 20. Generation and characterization of a high-affinity chimaeric antibody against hepatitis B surface antigen.
    Bose B, Khanna N, Acharya SK, Sinha S.
    Biotechnol Appl Biochem; 2006 Feb 24; 43(Pt 2):93-101. PubMed ID: 16253117
    [Abstract] [Full Text] [Related]

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