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Journal Abstract Search

113 related items for PubMed ID: 10681368

  • 1. Bioactivation and covalent binding of hydroxyfluperlapine in human neutrophils: implications for fluperlapine-induced agranulocytosis.
    Lai WG, Gardner I, Zahid N, Uetrecht JP.
    Drug Metab Dispos; 2000 Mar; 28(3):255-63. PubMed ID: 10681368
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  • 2. Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells.
    Liu ZC, Uetrecht JP.
    J Pharmacol Exp Ther; 1995 Dec; 275(3):1476-83. PubMed ID: 8531118
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  • 3. Oxidation of a metabolite of indomethacin (Desmethyldeschlorobenzoylindomethacin) to reactive intermediates by activated neutrophils, hypochlorous acid, and the myeloperoxidase system.
    Ju C, Uetrecht JP.
    Drug Metab Dispos; 1998 Jul; 26(7):676-80. PubMed ID: 9660850
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  • 4. Structural features associated with reactive metabolite formation in clozapine analogues.
    Uetrecht J, Zahid N, Tehim A, Fu JM, Rakhit S.
    Chem Biol Interact; 1997 May 02; 104(2-3):117-29. PubMed ID: 9212779
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  • 6. Metabolism of ticlopidine by activated neutrophils: implications for ticlopidine-induced agranulocytosis.
    Liu ZC, Uetrecht JP.
    Drug Metab Dispos; 2000 Jul 02; 28(7):726-30. PubMed ID: 10859143
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  • 11. Neutrophil- and myeloperoxidase-mediated metabolism of reduced nimesulide: evidence for bioactivation.
    Yang M, Chordia MD, Li F, Huang T, Linden J, Macdonald TL.
    Chem Res Toxicol; 2010 Nov 15; 23(11):1691-700. PubMed ID: 20939553
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  • 12. Oxidation of diclofenac to reactive intermediates by neutrophils, myeloperoxidase, and hypochlorous acid.
    Miyamoto G, Zahid N, Uetrecht JP.
    Chem Res Toxicol; 1997 Apr 15; 10(4):414-9. PubMed ID: 9114978
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  • 16. Involvement of myeloperoxidase and NADPH oxidase in the covalent binding of amodiaquine and clozapine to neutrophils: implications for drug-induced agranulocytosis.
    Lobach AR, Uetrecht J.
    Chem Res Toxicol; 2014 Apr 21; 27(4):699-709. PubMed ID: 24588327
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  • 18. Potential role of a quetiapine metabolite in quetiapine-induced neutropenia and agranulocytosis.
    Li X, Cameron MD.
    Chem Res Toxicol; 2012 May 21; 25(5):1004-11. PubMed ID: 22506851
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  • 20. Effect of clozapine and olanzapine on neutrophil kinetics: implications for drug-induced agranulocytosis.
    Ng W, Kennar R, Uetrecht J.
    Chem Res Toxicol; 2014 Jul 21; 27(7):1104-8. PubMed ID: 24968069
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