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214 related items for PubMed ID: 10684862

  • 1. Lck domains differentially contribute to pre-T cell receptor (TCR)- and TCR-alpha/beta-regulated developmental transitions.
    Lin K, Longo NS, Wang X, Hewitt JA, Abraham KM.
    J Exp Med; 2000 Feb 21; 191(4):703-16. PubMed ID: 10684862
    [Abstract] [Full Text] [Related]

  • 2. Autonomous maturation of alpha/beta T lineage cells in the absence of COOH-terminal Src kinase (Csk).
    Schmedt C, Tarakhovsky A.
    J Exp Med; 2001 Apr 02; 193(7):815-26. PubMed ID: 11283154
    [Abstract] [Full Text] [Related]

  • 3. Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule.
    Tsujikawa K, Ichijo T, Moriyama K, Tadotsu N, Sakamoto K, Sakane N, Fukada S, Furukawa T, Saito H, Yamamoto H.
    Mol Cancer Res; 2002 Dec 02; 1(2):155-63. PubMed ID: 12496362
    [Abstract] [Full Text] [Related]

  • 4. T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR beta locus is incomplete but thymocyte development is not restored by TcR beta or TcR alpha beta transgenes.
    Wallace VA, Kawai K, Levelt CN, Kishihara K, Molina T, Timms E, Pircher H, Penninger J, Ohashi PS, Eichmann K.
    Eur J Immunol; 1995 May 02; 25(5):1312-8. PubMed ID: 7774634
    [Abstract] [Full Text] [Related]

  • 5. Enrichment of lck in lipid rafts regulates colocalized fyn activation and the initiation of proximal signals through TCR alpha beta.
    Filipp D, Leung BL, Zhang J, Veillette A, Julius M.
    J Immunol; 2004 Apr 01; 172(7):4266-74. PubMed ID: 15034040
    [Abstract] [Full Text] [Related]

  • 6. Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression.
    Chu DH, van Oers NS, Malissen M, Harris J, Elder M, Weiss A.
    J Immunol; 1999 Sep 01; 163(5):2610-20. PubMed ID: 10453000
    [Abstract] [Full Text] [Related]

  • 7. The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus.
    Eyquem S, Chemin K, Fasseu M, Bories JC.
    Proc Natl Acad Sci U S A; 2004 Nov 02; 101(44):15712-7. PubMed ID: 15496469
    [Abstract] [Full Text] [Related]

  • 8. T-cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages.
    Chiang YJ, Hodes RJ.
    Eur J Immunol; 2016 Oct 02; 46(10):2401-2408. PubMed ID: 27469439
    [Abstract] [Full Text] [Related]

  • 9. Activated p56lck directs maturation of both CD4 and CD8 single-positive thymocytes.
    Sohn SJ, Forbush KA, Pan XC, Perlmutter RM.
    J Immunol; 2001 Feb 15; 166(4):2209-17. PubMed ID: 11160274
    [Abstract] [Full Text] [Related]

  • 10. Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation.
    Na SY, Patra A, Scheuring Y, Marx A, Tolaini M, Kioussis D, Hemmings BA, Hünig T, Bommhardt U.
    J Immunol; 2003 Aug 01; 171(3):1285-96. PubMed ID: 12874217
    [Abstract] [Full Text] [Related]

  • 11. Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.
    Stephen TL, Wilson BS, Laufer TM.
    Proc Natl Acad Sci U S A; 2012 May 08; 109(19):7415-20. PubMed ID: 22529380
    [Abstract] [Full Text] [Related]

  • 12. Differential contribution of Lck and Fyn protein tyrosine kinases to intraepithelial lymphocyte development.
    Page ST, van Oers NS, Perlmutter RM, Weiss A, Pullen AM.
    Eur J Immunol; 1997 Feb 08; 27(2):554-62. PubMed ID: 9045930
    [Abstract] [Full Text] [Related]

  • 13. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity.
    Azzam HS, Grinberg A, Lui K, Shen H, Shores EW, Love PE.
    J Exp Med; 1998 Dec 21; 188(12):2301-11. PubMed ID: 9858516
    [Abstract] [Full Text] [Related]

  • 14. Allelic exclusion of the TCR alpha-chain is an active process requiring TCR-mediated signaling and c-Cbl.
    Niederberger N, Holmberg K, Alam SM, Sakati W, Naramura M, Gu H, Gascoigne NR.
    J Immunol; 2003 May 01; 170(9):4557-63. PubMed ID: 12707333
    [Abstract] [Full Text] [Related]

  • 15. A CD8/Lck transgene is able to drive thymocyte differentiation.
    Fragoso RC, Pyarajan S, Irie HY, Burakoff SJ.
    J Immunol; 2006 Nov 01; 177(9):6007-17. PubMed ID: 17056525
    [Abstract] [Full Text] [Related]

  • 16. Lck activity controls CD4/CD8 T cell lineage commitment.
    Hernández-Hoyos G, Sohn SJ, Rothenberg EV, Alberola-Ila J.
    Immunity; 2000 Mar 01; 12(3):313-22. PubMed ID: 10755618
    [Abstract] [Full Text] [Related]

  • 17. Restoration of NK T cell development in fyn-mutant mice by a TCR reveals a requirement for Fyn during early NK T cell ontogeny.
    Gadue P, Yin L, Jain S, Stein PL.
    J Immunol; 2004 May 15; 172(10):6093-100. PubMed ID: 15128794
    [Abstract] [Full Text] [Related]

  • 18. ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
    Ashe JM, Wiest DL, Abe R, Singer A.
    J Exp Med; 1999 Apr 05; 189(7):1163-8. PubMed ID: 10190908
    [Abstract] [Full Text] [Related]

  • 19. TCR signals mediated by Src family kinases are essential for the survival of naive T cells.
    Seddon B, Zamoyska R.
    J Immunol; 2002 Sep 15; 169(6):2997-3005. PubMed ID: 12218114
    [Abstract] [Full Text] [Related]

  • 20. A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis.
    Barndt R, Dai MF, Zhuang Y.
    J Immunol; 1999 Sep 15; 163(6):3331-43. PubMed ID: 10477603
    [Abstract] [Full Text] [Related]

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