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261 related items for PubMed ID: 10686588

  • 1. Lactacystin, a specific inhibitor of the proteasome, induces apoptosis and activates caspase-3 in cultured cerebellar granule cells.
    Pasquini LA, Besio Moreno M, Adamo AM, Pasquini JM, Soto EF.
    J Neurosci Res; 2000 Mar 01; 59(5):601-11. PubMed ID: 10686588
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells.
    Zhang XM, Lin H, Chen C, Chen BD.
    Biochem J; 1999 May 15; 340 ( Pt 1)(Pt 1):127-33. PubMed ID: 10229667
    [Abstract] [Full Text] [Related]

  • 3. p27Kip1 accumulation by inhibition of proteasome function induces apoptosis in oral squamous cell carcinoma cells.
    Kudo Y, Takata T, Ogawa I, Kaneda T, Sato S, Takekoshi T, Zhao M, Miyauchi M, Nikai H.
    Clin Cancer Res; 2000 Mar 15; 6(3):916-23. PubMed ID: 10741716
    [Abstract] [Full Text] [Related]

  • 4. Early mitochondrial hyperpolarization and intracellular alkalinization in lactacystin-induced apoptosis of retinal pigment epithelial cells.
    Kim JM, Bae HR, Park BS, Lee JM, Ahn HB, Rho JH, Yoo KW, Park WC, Rho SH, Yoon HS, Yoo YH.
    J Pharmacol Exp Ther; 2003 May 15; 305(2):474-81. PubMed ID: 12606642
    [Abstract] [Full Text] [Related]

  • 5. Caspase and proteasome activity during staurosporin-induced apoptosis in lens epithelial cells.
    Andersson M, Sjöstrand J, Petersen A, Honarvar AK, Karlsson JO.
    Invest Ophthalmol Vis Sci; 2000 Aug 15; 41(9):2623-32. PubMed ID: 10937575
    [Abstract] [Full Text] [Related]

  • 6. Proteasome involvement and accumulation of ubiquitinated proteins in cerebellar granule neurons undergoing apoptosis.
    Canu N, Barbato C, Ciotti MT, Serafino A, Dus L, Calissano P.
    J Neurosci; 2000 Jan 15; 20(2):589-99. PubMed ID: 10632588
    [Abstract] [Full Text] [Related]

  • 7. Proteasome inhibitors induced caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells.
    Naujokat C, Sezer O, Zinke H, Leclere A, Hauptmann S, Possinger K.
    Eur J Haematol; 2000 Oct 15; 65(4):221-36. PubMed ID: 11073163
    [Abstract] [Full Text] [Related]

  • 8. Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.
    Sadoul R, Fernandez PA, Quiquerez AL, Martinou I, Maki M, Schröter M, Becherer JD, Irmler M, Tschopp J, Martinou JC.
    EMBO J; 1996 Aug 01; 15(15):3845-52. PubMed ID: 8670889
    [Abstract] [Full Text] [Related]

  • 9. The involvement of proteasome in myogenic differentiation of murine myocytes and human rhabdomyosarcoma cells.
    Mugita N, Honda Y, Nakamura H, Fujiwara T, Tanaka K, Omura S, Shimbara N, Ogawa M, Saya H, Nakao M.
    Int J Mol Med; 1999 Feb 01; 3(2):127-37. PubMed ID: 9917519
    [Abstract] [Full Text] [Related]

  • 10. Lactacystin, a proteasome inhibitor, potentiates the apoptotic effect of parthenolide, an inhibitor of NFkappaB activation, on drug-resistant mouse leukemia L1210 cells.
    Cory AH, Cory JG.
    Anticancer Res; 2002 Feb 01; 22(6C):3805-9. PubMed ID: 12552998
    [Abstract] [Full Text] [Related]

  • 11. Preservation of caspase-3 subunits from degradation contributes to apoptosis evoked by lactacystin: any single lysine or lysine pair of the small subunit is sufficient for ubiquitination.
    Chen L, Smith L, Wang Z, Smith JB.
    Mol Pharmacol; 2003 Aug 01; 64(2):334-45. PubMed ID: 12869638
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of proteasome function induced apoptosis in gastric cancer.
    Fan XM, Wong BC, Wang WP, Zhou XM, Cho CH, Yuen ST, Leung SY, Lin MC, Kung HF, Lam SK.
    Int J Cancer; 2001 Aug 15; 93(4):481-8. PubMed ID: 11477551
    [Abstract] [Full Text] [Related]

  • 13. Activation of the cell death program by inhibition of proteasome function.
    Drexler HC.
    Proc Natl Acad Sci U S A; 1997 Feb 04; 94(3):855-60. PubMed ID: 9023346
    [Abstract] [Full Text] [Related]

  • 14. Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: a microarray analysis.
    Yew EH, Cheung NS, Choy MS, Qi RZ, Lee AY, Peng ZF, Melendez AJ, Manikandan J, Koay ES, Chiu LL, Ng WL, Whiteman M, Kandiah J, Halliwell B.
    J Neurochem; 2005 Aug 04; 94(4):943-56. PubMed ID: 15992382
    [Abstract] [Full Text] [Related]

  • 15. Apoptosis of Ewing's sarcoma cells is accompanied by accumulation of ubiquitinated proteins.
    Soldatenkov VA, Dritschilo A.
    Cancer Res; 1997 Sep 15; 57(18):3881-5. PubMed ID: 9307264
    [Abstract] [Full Text] [Related]

  • 16. Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells.
    Imajoh-Ohmi S, Kawaguchi T, Sugiyama S, Tanaka K, Omura S, Kikuchi H.
    Biochem Biophys Res Commun; 1995 Dec 26; 217(3):1070-7. PubMed ID: 8554559
    [Abstract] [Full Text] [Related]

  • 17. The ubiquitin-proteasome system and cellular proliferation and regulation in osteoblastic cells.
    Murray EJ, Bentley GV, Grisanti MS, Murray SS.
    Exp Cell Res; 1998 Aug 01; 242(2):460-9. PubMed ID: 9683533
    [Abstract] [Full Text] [Related]

  • 18. Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways.
    Bogner C, Schneller F, Hipp S, Ringshausen I, Peschel C, Decker T.
    Exp Hematol; 2003 Mar 01; 31(3):218-25. PubMed ID: 12644019
    [Abstract] [Full Text] [Related]

  • 19. Influence of p53 and p21Waf1 expression on G2/M phase arrest of colorectal carcinoma HCT116 cells to proteasome inhibitors.
    Kim OH, Lim JH, Woo KJ, Kim YH, Jin IN, Han ST, Park JW, Kwon TK.
    Int J Oncol; 2004 Apr 01; 24(4):935-41. PubMed ID: 15010833
    [Abstract] [Full Text] [Related]

  • 20. The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells is mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32.
    Vaudry D, Gonzalez BJ, Basille M, Pamantung TF, Fontaine M, Fournier A, Vaudry H.
    Proc Natl Acad Sci U S A; 2000 Nov 21; 97(24):13390-5. PubMed ID: 11087878
    [Abstract] [Full Text] [Related]

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