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Journal Abstract Search

575 related items for PubMed ID: 10691681

  • 1. Novel ligands lacking a positive charge for the delta- and mu-opioid receptors.
    Schiller PW, Berezowska I, Nguyen TM, Schmidt R, Lemieux C, Chung NN, Falcone-Hindley ML, Yao W, Liu J, Iwama S, Smith AB, Hirschmann R.
    J Med Chem; 2000 Feb 24; 43(4):551-9. PubMed ID: 10691681
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  • 5. Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity.
    Salvadori S, Balboni G, Guerrini R, Tomatis R, Bianchi C, Bryant SD, Cooper PS, Lazarus LH.
    J Med Chem; 1997 Sep 12; 40(19):3100-8. PubMed ID: 9301674
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  • 9. Delta opioidmimetic antagonists: prototypes for designing a new generation of ultraselective opioid peptides.
    Salvadori S, Attila M, Balboni G, Bianchi C, Bryant SD, Crescenzi O, Guerrini R, Picone D, Tancredi T, Temussi PA.
    Mol Med; 1995 Sep 12; 1(6):678-89. PubMed ID: 8529134
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  • 11. Bifunctional [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues substituted at position 3 with alkylated phenylalanine derivatives yield potent mixed mu-agonist/delta-antagonist and dual mu-agonist/delta-agonist opioid ligands.
    Li T, Shiotani K, Miyazaki A, Tsuda Y, Ambo A, Sasaki Y, Jinsmaa Y, Marczak E, Bryant SD, Lazarus LH, Okada Y.
    J Med Chem; 2007 Jun 14; 50(12):2753-66. PubMed ID: 17497839
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  • 13. The opioid mu agonist/delta antagonist DIPP-NH(2)[Psi] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in rats.
    Schiller PW, Fundytus ME, Merovitz L, Weltrowska G, Nguyen TM, Lemieux C, Chung NN, Coderre TJ.
    J Med Chem; 1999 Sep 09; 42(18):3520-6. PubMed ID: 10479285
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  • 15. Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists.
    Schiller PW, Nguyen TM, Weltrowska G, Wilkes BC, Marsden BJ, Lemieux C, Chung NN.
    Proc Natl Acad Sci U S A; 1992 Dec 15; 89(24):11871-5. PubMed ID: 1334552
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  • 16. Effect of aromatic amino acid substitutions in the 3-position of cyclic beta-casomorphin analogues on mu-opioid agonist/delta-opioid antagonist properties.
    Schmidt R, Wilkes BC, Chung NN, Lemieux C, Schiller PW.
    Int J Pept Protein Res; 1996 Nov 15; 48(5):411-9. PubMed ID: 8956074
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  • 17. The cis-4-amino-L-proline residue as a scaffold for the synthesis of cyclic and linear endomorphin-2 analogues.
    Mollica A, Pinnen F, Stefanucci A, Feliciani F, Campestre C, Mannina L, Sobolev AP, Lucente G, Davis P, Lai J, Ma SW, Porreca F, Hruby VJ.
    J Med Chem; 2012 Apr 12; 55(7):3027-35. PubMed ID: 22394120
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  • 18. Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.
    McLamore S, Ullrich T, Rothman RB, Xu H, Dersch C, Coop A, Davis P, Porreca F, Jacobson AE, Rice KC.
    J Med Chem; 2001 Apr 26; 44(9):1471-4. PubMed ID: 11311071
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  • 19. Pseudoproline-containing analogues of morphiceptin and endomorphin-2: evidence for a cis Tyr-Pro amide bond in the bioactive conformation.
    Keller M, Boissard C, Patiny L, Chung NN, Lemieux C, Mutter M, Schiller PW.
    J Med Chem; 2001 Nov 08; 44(23):3896-903. PubMed ID: 11689075
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