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535 related items for PubMed ID: 10695663

  • 1. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts.
    Honda A, Salen G, Honda M, Batta AK, Tint GS, Xu G, Chen TS, Tanaka N, Shefer S.
    J Lab Clin Med; 2000 Feb; 135(2):174-9. PubMed ID: 10695663
    [Abstract] [Full Text] [Related]

  • 2. Macrophage 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in sitosterolemia: effects of increased cellular cholesterol and sitosterol concentrations.
    Nguyen LB, Salen G, Shefer S, Tint GS, Ruiz F.
    Metabolism; 2001 Oct; 50(10):1224-9. PubMed ID: 11586498
    [Abstract] [Full Text] [Related]

  • 3. The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolemic homozygotes.
    Shefer S, Salen G, Bullock J, Nguyen LB, Ness GC, Vhao Z, Belamarich PF, Chowdhary I, Lerner S, Batta AK.
    Hepatology; 1994 Jul; 20(1 Pt 1):213-9. PubMed ID: 8020891
    [Abstract] [Full Text] [Related]

  • 4. Deficient ileal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: sitosterol is not a feedback inhibitor of intestinal cholesterol biosynthesis.
    Nguyen LB, Salen G, Shefer S, Bullock J, Chen T, Tint GS, Chowdhary IR, Lerner S.
    Metabolism; 1994 Jul; 43(7):855-9. PubMed ID: 8028508
    [Abstract] [Full Text] [Related]

  • 5. Regulation of early cholesterol biosynthesis in rat liver: effects of sterols, bile acids, lovastatin, and BM 15.766 on 3-hydroxy-3-methylglutaryl coenzyme A synthase and acetoacetyl coenzyme A thiolase activities.
    Honda A, Salen G, Nguyen LB, Xu G, Tint GS, Batta AK, Shefer S.
    Hepatology; 1998 Jan; 27(1):154-9. PubMed ID: 9425931
    [Abstract] [Full Text] [Related]

  • 6. Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function.
    Nguyen LB, Salen G, Shefer S, Tint GS, Shore V, Ness GC.
    Metabolism; 1990 Apr; 39(4):436-43. PubMed ID: 2325562
    [Abstract] [Full Text] [Related]

  • 7. Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells.
    Jesch ED, Seo JM, Carr TP, Lee JY.
    Nutr Res; 2009 Dec; 29(12):859-66. PubMed ID: 19963159
    [Abstract] [Full Text] [Related]

  • 8. Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol delta7-reductase in liver and mononuclear leukocytes.
    Honda A, Salen G, Nguyen LB, Tint GS, Batta AK, Shefer S.
    J Lipid Res; 1998 Jan; 39(1):44-50. PubMed ID: 9469584
    [Abstract] [Full Text] [Related]

  • 9. Comparative effect of dietary sitosterol on plasma sterols and cholesterol and bile acid synthesis in a sitosterolemic homozygote and heterozygote subject.
    Cobb MM, Salen G, Tint GS.
    J Am Coll Nutr; 1997 Dec; 16(6):605-13. PubMed ID: 9430090
    [Abstract] [Full Text] [Related]

  • 10. Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia.
    Nguyen LB, Shefer S, Salen G, Tint SG, Batta AK.
    Proc Assoc Am Physicians; 1998 Dec; 110(1):32-9. PubMed ID: 9460081
    [Abstract] [Full Text] [Related]

  • 11. Control of 3-hydroxy-3-methylglutaryl-CoA reductase activity in cultured human fibroblasts by very low density lipoproteins of subjects with hypertriglyceridemia.
    Gianturco SH, Gotto AM, Jackson RL, Patsch JR, Sybers HD, Taunton OD, Yeshurun DL, Smith LC.
    J Clin Invest; 1978 Feb; 61(2):320-8. PubMed ID: 202612
    [Abstract] [Full Text] [Related]

  • 12. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate.
    Straka MS, Panini SR.
    Arch Biochem Biophys; 1995 Feb 20; 317(1):235-43. PubMed ID: 7872789
    [Abstract] [Full Text] [Related]

  • 13. Regulation of cholesterol biosynthesis in sitosterolemia: effects of lovastatin, cholestyramine, and dietary sterol restriction.
    Nguyen LB, Cobb M, Shefer S, Salen G, Ness GC, Tint GS.
    J Lipid Res; 1991 Dec 20; 32(12):1941-8. PubMed ID: 1816322
    [Abstract] [Full Text] [Related]

  • 14. A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis.
    Nguyen LB, Shefer S, Salen G, Ness GC, Tint GS, Zaki FG, Rani I.
    J Clin Invest; 1990 Sep 20; 86(3):923-31. PubMed ID: 2394840
    [Abstract] [Full Text] [Related]

  • 15. Dietary cholesterol regulates hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in rats primarily at the level of translation.
    Chambers CM, Ness GC.
    Arch Biochem Biophys; 1998 Jun 15; 354(2):317-22. PubMed ID: 9637742
    [Abstract] [Full Text] [Related]

  • 16. [Studies on the regulatory factors of 3-hydroxy-3-methylglutaryl CoA reductase (HMG CoA reductase) activity].
    Ozasa S.
    Hokkaido Igaku Zasshi; 1976 Jul 15; 51(4):313-25. PubMed ID: 187533
    [Abstract] [Full Text] [Related]

  • 17. Modulation of rat liver 3-hydroxy-3-methylglutaryl-CoA reductase activity by reversible phosphorylation.
    Beg ZH, Brewer HB.
    Fed Proc; 1982 Aug 15; 41(10):2634-8. PubMed ID: 6286363
    [Abstract] [Full Text] [Related]

  • 18. Regulation of the last two enzymatic reactions in cholesterol biosynthesis in rats: effects of BM 15.766, cholesterol, cholic acid, lovastatin, and their combinations.
    Honda A, Shefer S, Salen G, Xu G, Batta AK, Tint GS, Honda M, Chen TC, Holick MF.
    Hepatology; 1996 Aug 15; 24(2):435-9. PubMed ID: 8690416
    [Abstract] [Full Text] [Related]

  • 19. Sitosterolemia: exclusion of genes involved in reduced cholesterol biosynthesis.
    Patel SB, Honda A, Salen G.
    J Lipid Res; 1998 May 15; 39(5):1055-61. PubMed ID: 9610773
    [Abstract] [Full Text] [Related]

  • 20. Mevalonic acid products as mediators of cell proliferation in simian virus 40-transformed 3T3 cells.
    Larsson O, Johansson BM.
    Cancer Res; 1987 Sep 15; 47(18):4825-9. PubMed ID: 3040232
    [Abstract] [Full Text] [Related]

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