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Journal Abstract Search

97 related items for PubMed ID: 10698522

  • 1. A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.
    Blalock WL, Pearce M, Steelman LS, Franklin RA, McCarthy SA, Cherwinski H, McMahon M, McCubrey JA.
    Oncogene; 2000 Jan 27; 19(4):526-36. PubMed ID: 10698522
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  • 2. Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells.
    Blalock WL, Pearce M, Chang F, Lee JT, Pohnert SC, Burrows C, Steelman LS, Franklin RA, McMahon M, McCubrey JA.
    Leukemia; 2001 May 27; 15(5):794-807. PubMed ID: 11368441
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  • 3. Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.
    Hoyle PE, Moye PW, Steelman LS, Blalock WL, Franklin RA, Pearce M, Cherwinski H, Bosch E, McMahon M, McCubrey JA.
    Leukemia; 2000 Apr 27; 14(4):642-56. PubMed ID: 10764150
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  • 4. Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.
    Blalock WL, Moye PW, Chang F, Pearce M, Steelman LS, McMahon M, McCubrey JA.
    Leukemia; 2000 Jun 27; 14(6):1080-96. PubMed ID: 10865974
    [Abstract] [Full Text] [Related]

  • 5. Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.
    Blalock WL, Navolanic PM, Steelman LS, Shelton JG, Moye PW, Lee JT, Franklin RA, Mirza A, McMahon M, White MK, McCubrey JA.
    Leukemia; 2003 Jun 27; 17(6):1058-67. PubMed ID: 12764369
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  • 6. Ability of the activated PI3K/Akt oncoproteins to synergize with MEK1 and induce cell cycle progression and abrogate the cytokine-dependence of hematopoietic cells.
    Shelton JG, Blalock WL, White ER, Steelman LS, McCubrey JA.
    Cell Cycle; 2004 Apr 27; 3(4):503-12. PubMed ID: 15004527
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  • 7. Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells.
    McCubrey JA, Steelman LS, Hoyle PE, Blalock WL, Weinstein-Oppenheimer C, Franklin RA, Cherwinski H, Bosch E, McMahon M.
    Leukemia; 1998 Dec 27; 12(12):1903-29. PubMed ID: 9844921
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  • 9. Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.
    Konopleva M, Shi Y, Steelman LS, Shelton JG, Munsell M, Marini F, McQueen T, Contractor R, McCubrey JA, Andreeff M.
    Cancer Res; 2005 Nov 01; 65(21):9962-70. PubMed ID: 16267021
    [Abstract] [Full Text] [Related]

  • 10. Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation.
    Shelton JG, Moye PW, Steelman LS, Blalock WL, Lee JT, Franklin RA, McMahon M, McCubrey JA.
    Leukemia; 2003 Sep 01; 17(9):1765-82. PubMed ID: 12970777
    [Abstract] [Full Text] [Related]

  • 11. Autocrine transformation of human hematopoietic cells after transfection with an activated granulocyte/macrophage colony stimulating factor gene.
    Hoyle PE, Steelman LS, McCubrey JA.
    Cytokines Cell Mol Ther; 1997 Sep 01; 3(3):159-68. PubMed ID: 9426974
    [Abstract] [Full Text] [Related]

  • 12. Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells.
    McCubrey JA, Lee JT, Steelman LS, Blalock WL, Moye PW, Chang F, Pearce M, Shelton JG, White MK, Franklin RA, Pohnert SC.
    Cancer Detect Prev; 2001 Sep 01; 25(4):375-93. PubMed ID: 11531015
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  • 13. Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells.
    McCubrey JA, Shelton JG, Steelman LS, Franklin RA, Sreevalsan T, McMahon M.
    Oncogene; 2004 Oct 14; 23(47):7810-20. PubMed ID: 15361836
    [Abstract] [Full Text] [Related]

  • 14. Characterization of factor-independent variants derived from TF-1 hematopoietic progenitor cells: the role of the Raf/MAP kinase pathway in the anti-apoptotic effect of GM-CSF.
    Chao JR, Chen CS, Wang TF, Tseng LH, Tsai JJ, Kuo ML, Yen JJ, Yang Yen HF.
    Oncogene; 1997 Feb 13; 14(6):721-8. PubMed ID: 9038380
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  • 18. Activated Raf-1 causes growth arrest in human small cell lung cancer cells.
    Ravi RK, Weber E, McMahon M, Williams JR, Baylin S, Mal A, Harter ML, Dillehay LE, Claudio PP, Giordano A, Nelkin BD, Mabry M.
    J Clin Invest; 1998 Jan 01; 101(1):153-9. PubMed ID: 9421477
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  • 20. Effect of estradiol on estrogen receptor-alpha gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway.
    Stoica GE, Franke TF, Moroni M, Mueller S, Morgan E, Iann MC, Winder AD, Reiter R, Wellstein A, Martin MB, Stoica A.
    Oncogene; 2003 Sep 11; 22(39):7998-8011. PubMed ID: 12970748
    [Abstract] [Full Text] [Related]

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