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Journal Abstract Search

901 related items for PubMed ID: 10698680

  • 1. The PI3K-PDK1 connection: more than just a road to PKB.
    Vanhaesebroeck B, Alessi DR.
    Biochem J; 2000 Mar 15; 346 Pt 3(Pt 3):561-76. PubMed ID: 10698680
    [Abstract] [Full Text] [Related]

  • 2. PDK1 and PKB/Akt: ideal targets for development of new strategies to structure-based drug design.
    Harris TK.
    IUBMB Life; 2003 Mar 15; 55(3):117-26. PubMed ID: 12822887
    [Abstract] [Full Text] [Related]

  • 3. Regulation of protein kinase B.
    Meier R, Hemmings BA.
    J Recept Signal Transduct Res; 1999 Mar 15; 19(1-4):121-8. PubMed ID: 10071752
    [Abstract] [Full Text] [Related]

  • 4. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2.
    Kobayashi T, Cohen P.
    Biochem J; 1999 Apr 15; 339 ( Pt 2)(Pt 2):319-28. PubMed ID: 10191262
    [Abstract] [Full Text] [Related]

  • 5. Differential activation of the phosphatidylinositol 3'-kinase/Akt survival pathway by ionizing radiation in tumor and primary endothelial cells.
    Zingg D, Riesterer O, Fabbro D, Glanzmann C, Bodis S, Pruschy M.
    Cancer Res; 2004 Aug 01; 64(15):5398-406. PubMed ID: 15289348
    [Abstract] [Full Text] [Related]

  • 6. p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes.
    Genot E, Reif K, Beach S, Kramer I, Cantrell D.
    Oncogene; 1998 Oct 01; 17(13):1731-8. PubMed ID: 9796702
    [Abstract] [Full Text] [Related]

  • 7. Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
    Milburn CC, Deak M, Kelly SM, Price NC, Alessi DR, Van Aalten DM.
    Biochem J; 2003 Nov 01; 375(Pt 3):531-8. PubMed ID: 12964941
    [Abstract] [Full Text] [Related]

  • 8. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.
    Kandel ES, Hay N.
    Exp Cell Res; 1999 Nov 25; 253(1):210-29. PubMed ID: 10579924
    [Abstract] [Full Text] [Related]

  • 9. Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes.
    Yamada T, Katagiri H, Asano T, Tsuru M, Inukai K, Ono H, Kodama T, Kikuchi M, Oka Y.
    Am J Physiol Endocrinol Metab; 2002 Jun 25; 282(6):E1385-94. PubMed ID: 12006370
    [Abstract] [Full Text] [Related]

  • 10. 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.
    Alessi DR, Deak M, Casamayor A, Caudwell FB, Morrice N, Norman DG, Gaffney P, Reese CB, MacDougall CN, Harbison D, Ashworth A, Bownes M.
    Curr Biol; 1997 Oct 01; 7(10):776-89. PubMed ID: 9368760
    [Abstract] [Full Text] [Related]

  • 11. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.
    Cancer Res; 2000 Jul 01; 60(13):3504-13. PubMed ID: 10910062
    [Abstract] [Full Text] [Related]

  • 12. PI3K/Akt signalling pathway and cancer.
    Fresno Vara JA, Casado E, de Castro J, Cejas P, Belda-Iniesta C, González-Barón M.
    Cancer Treat Rev; 2004 Apr 01; 30(2):193-204. PubMed ID: 15023437
    [Abstract] [Full Text] [Related]

  • 13. [Protein kinase B and its role in the signal transduction pathway mediated by phosphoinositide 3-kinase].
    Zou W, Li ZY, Li CL, Cui ZC.
    Sheng Li Ke Xue Jin Zhan; 2000 Apr 01; 31(2):120-4. PubMed ID: 12545728
    [Abstract] [Full Text] [Related]

  • 14. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction.
    Burgering BM, Coffer PJ.
    Nature; 1995 Aug 17; 376(6541):599-602. PubMed ID: 7637810
    [Abstract] [Full Text] [Related]

  • 15. Effect of overexpression and nuclear translocation of constitutively active PKB-alpha on cellular survival and proliferation in HepG2 cells.
    Gupta D, Syed NA, Roesler WJ, Khandelwal RL.
    J Cell Biochem; 2004 Oct 15; 93(3):513-25. PubMed ID: 15372623
    [Abstract] [Full Text] [Related]

  • 16. Sustained Akt/PKB activation and transient attenuation of c-jun N-terminal kinase in the inhibition of apoptosis by IGF-1 in vascular smooth muscle cells.
    Allen RT, Krueger KD, Dhume A, Agrawal DK.
    Apoptosis; 2005 May 15; 10(3):525-35. PubMed ID: 15909115
    [Abstract] [Full Text] [Related]

  • 17. Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.
    Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J.
    Biochem J; 1999 Feb 01; 337 ( Pt 3)(Pt 3):575-83. PubMed ID: 9895304
    [Abstract] [Full Text] [Related]

  • 18. Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor.
    Dijkers PF, van Dijk TB, de Groot RP, Raaijmakers JA, Lammers JW, Koenderman L, Coffer PJ.
    Oncogene; 1999 Jun 03; 18(22):3334-42. PubMed ID: 10362354
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1.
    Wick MJ, Dong LQ, Riojas RA, Ramos FJ, Liu F.
    J Biol Chem; 2000 Dec 22; 275(51):40400-6. PubMed ID: 11006271
    [Abstract] [Full Text] [Related]

  • 20. The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.
    Biondi RM, Kieloch A, Currie RA, Deak M, Alessi DR.
    EMBO J; 2001 Aug 15; 20(16):4380-90. PubMed ID: 11500365
    [Abstract] [Full Text] [Related]

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