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296 related items for PubMed ID: 10699179

  • 1. Developmentally distinct effects on human epsilon-, gamma- and delta-globin levels caused by the absence or altered position of the human beta-globin gene in YAC transgenic mice.
    Bauchwitz R, Costantini F.
    Hum Mol Genet; 2000 Mar 01; 9(4):561-74. PubMed ID: 10699179
    [Abstract] [Full Text] [Related]

  • 2. Juxtaposition of the HPFH2 enhancer is not sufficient to reactivate the gamma-globin gene in adult erythropoiesis.
    Xiang P, Han H, Barkess G, Olave I, Fang X, Yin W, Stamatoyannopoulos G, Li Q.
    Hum Mol Genet; 2005 Oct 15; 14(20):3047-56. PubMed ID: 16155112
    [Abstract] [Full Text] [Related]

  • 3. Correct function of the locus control region may require passage through a nonerythroid cellular environment.
    Vassilopoulos G, Navas PA, Skarpidi E, Peterson KR, Lowrey CH, Papayannopoulou T, Stamatoyannopoulos G.
    Blood; 1999 Jan 15; 93(2):703-12. PubMed ID: 9885233
    [Abstract] [Full Text] [Related]

  • 4. All of the human beta-type globin genes compete for LCR enhancer activity in embryonic erythroid cells of yeast artificial chromosome transgenic mice.
    Okamura E, Matsuzaki H, Campbell AD, Engel JD, Fukamizu A, Tanimoto K.
    FASEB J; 2009 Dec 15; 23(12):4335-43. PubMed ID: 19690216
    [Abstract] [Full Text] [Related]

  • 5. Deletion of the human beta-globin LCR 5'HS4 or 5'HS1 differentially affects beta-like globin gene expression in beta-YAC transgenic mice.
    Fedosyuk H, Peterson KR.
    Blood Cells Mol Dis; 2007 Dec 15; 39(1):44-55. PubMed ID: 17433733
    [Abstract] [Full Text] [Related]

  • 6. Coexpression of epsilon, G gamma and A gamma globin mRNA in embryonic red blood cells from a single copy beta-YAC transgenic mouse.
    Furukawa T, Navas PA, Josephson BM, Peterson KR, Papayannopoulou T, Stamatoyannopoulos G.
    Blood Cells Mol Dis; 1995 Dec 15; 21(2):168-78. PubMed ID: 8846046
    [Abstract] [Full Text] [Related]

  • 7. A 5' control region of the human epsilon-globin gene is sufficient for embryonic specificity in transgenic mice.
    Shih DM, Wall RJ, Shapiro SG.
    J Biol Chem; 1993 Feb 15; 268(5):3066-71. PubMed ID: 8428985
    [Abstract] [Full Text] [Related]

  • 8. Sequences located 3' to the breakpoint of the hereditary persistence of fetal hemoglobin-3 deletion exhibit enhancer activity and can modify the developmental expression of the human fetal A gamma-globin gene in transgenic mice.
    Anagnou NP, Perez-Stable C, Gelinas R, Costantini F, Liapaki K, Constantopoulou M, Kosteas T, Moschonas NK, Stamatoyannopoulos G.
    J Biol Chem; 1995 Apr 28; 270(17):10256-63. PubMed ID: 7537267
    [Abstract] [Full Text] [Related]

  • 9. Activation of the beta-like globin genes in transgenic mice is dependent on the presence of the beta-locus control region.
    Navas PA, Li Q, Peterson KR, Swank RA, Rohde A, Roy J, Stamatoyannopoulos G.
    Hum Mol Genet; 2002 Apr 15; 11(8):893-903. PubMed ID: 11971871
    [Abstract] [Full Text] [Related]

  • 10. Genome architecture of the human beta-globin locus affects developmental regulation of gene expression.
    Harju S, Navas PA, Stamatoyannopoulos G, Peterson KR.
    Mol Cell Biol; 2005 Oct 15; 25(20):8765-78. PubMed ID: 16199858
    [Abstract] [Full Text] [Related]

  • 11. DNase I hypersensitivity and epsilon-globin transcriptional enhancement are separable in locus control region (LCR) HS1 mutant human beta-globin YAC transgenic mice.
    Shimotsuma M, Okamura E, Matsuzaki H, Fukamizu A, Tanimoto K.
    J Biol Chem; 2010 May 07; 285(19):14495-503. PubMed ID: 20231293
    [Abstract] [Full Text] [Related]

  • 12. Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.
    Bungert J, Davé U, Lim KC, Lieuw KH, Shavit JA, Liu Q, Engel JD.
    Genes Dev; 1995 Dec 15; 9(24):3083-96. PubMed ID: 8543153
    [Abstract] [Full Text] [Related]

  • 13. Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.
    Peterson KR, Li QL, Clegg CH, Furukawa T, Navas PA, Norton EJ, Kimbrough TG, Stamatoyannopoulos G.
    Proc Natl Acad Sci U S A; 1995 Jun 06; 92(12):5655-9. PubMed ID: 7539923
    [Abstract] [Full Text] [Related]

  • 14. Human gamma-globin gene promoter element regulates human beta-globin gene developmental specificity.
    Ryan TM, Sun CW, Ren J, Townes TM.
    Nucleic Acids Res; 2000 Jul 15; 28(14):2736-40. PubMed ID: 10908330
    [Abstract] [Full Text] [Related]

  • 15. Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes.
    Navas PA, Swank RA, Yu M, Peterson KR, Stamatoyannopoulos G.
    Hum Mol Genet; 2003 Nov 15; 12(22):2941-8. PubMed ID: 14506128
    [Abstract] [Full Text] [Related]

  • 16. Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.
    Peterson KR, Clegg CH, Navas PA, Norton EJ, Kimbrough TG, Stamatoyannopoulos G.
    Proc Natl Acad Sci U S A; 1996 Jun 25; 93(13):6605-9. PubMed ID: 8692864
    [Abstract] [Full Text] [Related]

  • 17. Developmentally regulated and erythroid-specific expression of the human embryonic beta-globin gene in transgenic mice.
    Shih DM, Wall RJ, Shapiro SG.
    Nucleic Acids Res; 1990 Sep 25; 18(18):5465-72. PubMed ID: 2216720
    [Abstract] [Full Text] [Related]

  • 18. {gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice.
    Blau CA, Barbas CF, Bomhoff AL, Neades R, Yan J, Navas PA, Peterson KR.
    J Biol Chem; 2005 Nov 04; 280(44):36642-7. PubMed ID: 16131492
    [Abstract] [Full Text] [Related]

  • 19. Human beta-globin locus control region HS5 contains CTCF- and developmental stage-dependent enhancer-blocking activity in erythroid cells.
    Tanimoto K, Sugiura A, Omori A, Felsenfeld G, Engel JD, Fukamizu A.
    Mol Cell Biol; 2003 Dec 04; 23(24):8946-52. PubMed ID: 14645507
    [Abstract] [Full Text] [Related]

  • 20. Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression.
    Calzolari R, McMorrow T, Yannoutsos N, Langeveld A, Grosveld F.
    EMBO J; 1999 Feb 15; 18(4):949-58. PubMed ID: 10022837
    [Abstract] [Full Text] [Related]

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