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176 related items for PubMed ID: 10699949

  • 1. Resistance to methotrexate in SKOV-3 cell lines after chronic exposure to carbamazepine is associated with a decreased expression of folate receptor.
    Toffoli G, Corona G, Tolusso B, Sartor F, Sorio R, Mini E, Boiocchi M.
    Int J Cancer; 2000 Mar 01; 85(5):683-90. PubMed ID: 10699949
    [Abstract] [Full Text] [Related]

  • 2. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
    Mauritz R, Peters GJ, Priest DG, Assaraf YG, Drori S, Kathmann I, Noordhuis P, Bunni MA, Rosowsky A, Schornagel JH, Pinedo HM, Jansen G.
    Biochem Pharmacol; 2002 Jan 15; 63(2):105-15. PubMed ID: 11841783
    [Abstract] [Full Text] [Related]

  • 3. Decreased expression of the human folate receptor mediates transport-defective methotrexate resistance in KB cells.
    Saikawa Y, Knight CB, Saikawa T, Page ST, Chabner BA, Elwood PC.
    J Biol Chem; 1993 Mar 05; 268(7):5293-301. PubMed ID: 7680349
    [Abstract] [Full Text] [Related]

  • 4. Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines.
    Jackman AL, Kelland LR, Kimbell R, Brown M, Gibson W, Aherne GW, Hardcastle A, Boyle FT.
    Br J Cancer; 1995 May 05; 71(5):914-24. PubMed ID: 7537518
    [Abstract] [Full Text] [Related]

  • 5. Functional aspects of membrane folate receptors in human breast cancer cells with transport-related resistance to methotrexate.
    Pinard MF, Jolivet J, Ratnam M, Kathmann I, Molthoff C, Westerhof R, Schornagel JH, Jansen G.
    Cancer Chemother Pharmacol; 1996 May 05; 38(3):281-8. PubMed ID: 8646804
    [Abstract] [Full Text] [Related]

  • 6. Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line.
    Dixon KH, Trepel JB, Eng SC, Cowan KH.
    Cancer Commun; 1991 May 05; 3(12):357-65. PubMed ID: 16296001
    [Abstract] [Full Text] [Related]

  • 7. Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
    Miyachi H, Takemura Y, Kobayashi H, Ando Y.
    Jpn J Cancer Res; 1997 Sep 05; 88(9):900-6. PubMed ID: 9369939
    [Abstract] [Full Text] [Related]

  • 8. Reduced folate carrier gene (RFC1) expression and anti-folate resistance in transfected and non-selected cell lines.
    Moscow JA, Connolly T, Myers TG, Cheng CC, Paull K, Cowan KH.
    Int J Cancer; 1997 Jul 03; 72(1):184-90. PubMed ID: 9212241
    [Abstract] [Full Text] [Related]

  • 9. Antitumor activity of antifolate inhibitors of thymidylate and purine synthesis in human soft tissue sarcoma cell lines with intrinsic resistance to methotrexate.
    Li WW, Tong WP, Bertino JR.
    Clin Cancer Res; 1995 Jun 03; 1(6):631-6. PubMed ID: 9816025
    [Abstract] [Full Text] [Related]

  • 10. Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance.
    Jansen G, Westerhof GR, Kathmann I, Rademaker BC, Rijksen G, Schornagel JH.
    Cancer Res; 1989 May 01; 49(9):2455-9. PubMed ID: 2706633
    [Abstract] [Full Text] [Related]

  • 11. Role of folate receptor and reduced folate carrier in the transport of 5-methyltetrahydrofolic acid in human ovarian carcinoma cells.
    Corona G, Giannini F, Fabris M, Toffoli G, Boiocchi M.
    Int J Cancer; 1998 Jan 05; 75(1):125-33. PubMed ID: 9426700
    [Abstract] [Full Text] [Related]

  • 12. The folate receptor alpha is frequently overexpressed in osteosarcoma samples and plays a role in the uptake of the physiologic substrate 5-methyltetrahydrofolate.
    Yang R, Kolb EA, Qin J, Chou A, Sowers R, Hoang B, Healey JH, Huvos AG, Meyers PA, Gorlick R.
    Clin Cancer Res; 2007 May 01; 13(9):2557-67. PubMed ID: 17473184
    [Abstract] [Full Text] [Related]

  • 13. Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein.
    Westerhof GR, Rijnboutt S, Schornagel JH, Pinedo HM, Peters GJ, Jansen G.
    Cancer Res; 1995 Sep 01; 55(17):3795-802. PubMed ID: 7641196
    [Abstract] [Full Text] [Related]

  • 14. Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems.
    Westerhof GR, Jansen G, van Emmerik N, Kathmann I, Rijksen G, Jackman AL, Schornagel JH.
    Cancer Res; 1991 Oct 15; 51(20):5507-13. PubMed ID: 1655252
    [Abstract] [Full Text] [Related]

  • 15. P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in methotrexate accumulation due to a point mutation in the reduced folate carrier gene.
    Gifford AJ, Kavallaris M, Madafiglio J, Matherly LH, Stewart BW, Haber M, Norris MD.
    Int J Cancer; 1998 Oct 05; 78(2):176-81. PubMed ID: 9754649
    [Abstract] [Full Text] [Related]

  • 16. Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.
    Westerhof GR, Schornagel JH, Kathmann I, Jackman AL, Rosowsky A, Forsch RA, Hynes JB, Boyle FT, Peters GJ, Pinedo HM.
    Mol Pharmacol; 1995 Sep 05; 48(3):459-71. PubMed ID: 7565626
    [Abstract] [Full Text] [Related]

  • 17. Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors.
    Jansen G, Schornagel JH, Westerhof GR, Rijksen G, Newell DR, Jackman AL.
    Cancer Res; 1990 Dec 01; 50(23):7544-8. PubMed ID: 2253202
    [Abstract] [Full Text] [Related]

  • 18. Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells.
    Shen DW, Su A, Liang XJ, Pai-Panandiker A, Gottesman MM.
    Br J Cancer; 2004 Jul 19; 91(2):270-6. PubMed ID: 15199393
    [Abstract] [Full Text] [Related]

  • 19. Cross-resistance to methotrexate and metals in human cisplatin-resistant cell lines results from a pleiotropic defect in accumulation of these compounds associated with reduced plasma membrane binding proteins.
    Shen D, Pastan I, Gottesman MM.
    Cancer Res; 1998 Jan 15; 58(2):268-75. PubMed ID: 9443404
    [Abstract] [Full Text] [Related]

  • 20. Determinants of activity of the antifolate thymidylate synthase inhibitors Tomudex (ZD1694) and GW1843U89 against mono- and multilayered colon cancer cell lines under folate-restricted conditions.
    Peters GJ, Smitskamp-Wilms E, Smid K, Pinedo HM, Jansen G.
    Cancer Res; 1999 Nov 01; 59(21):5529-35. PubMed ID: 10554030
    [Abstract] [Full Text] [Related]

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