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171 related items for PubMed ID: 10708967

  • 1. Mutagenicity of benzo[a]pyrene-deoxyadenosine adducts in a sequence context derived from the p53 gene.
    Khalili H, Zhang FJ, Harvey RG, Dipple A.
    Mutat Res; 2000 Feb 16; 465(1-2):39-44. PubMed ID: 10708967
    [Abstract] [Full Text] [Related]

  • 2. Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: stable isotope-labeling mass spectrometry approach.
    Tretyakova N, Matter B, Jones R, Shallop A.
    Biochemistry; 2002 Jul 30; 41(30):9535-44. PubMed ID: 12135376
    [Abstract] [Full Text] [Related]

  • 3. Quantification of (7S,8R)-dihydroxy-(9R,10S)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene adducts in human serum albumin by laser-induced fluorescence: implications for the in vivo metabolism of benzo[a]pyrene.
    Ozbal CC, Skipper PL, Yu MC, London SJ, Dasari RR, Tannenbaum SR.
    Cancer Epidemiol Biomarkers Prev; 2000 Jul 30; 9(7):733-9. PubMed ID: 10919745
    [Abstract] [Full Text] [Related]

  • 4. The influence of cytosine methylation on the chemoselectivity of benzo[a]pyrene diol epoxide-oligonucleotide adducts determined using nanoLC/MS/MS.
    Glick J, Xiong W, Lin Y, Noronha AM, Wilds CJ, Vouros P.
    J Mass Spectrom; 2009 Aug 30; 44(8):1241-8. PubMed ID: 19536795
    [Abstract] [Full Text] [Related]

  • 5. A single site-specific trans-opened 7,8,9,10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct induces mutations at multiple sites in DNA.
    Kramata P, Zajc B, Sayer JM, Jerina DM, Wei CS.
    J Biol Chem; 2003 Apr 25; 278(17):14940-8. PubMed ID: 12595542
    [Abstract] [Full Text] [Related]

  • 6. Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.
    Denissenko MF, Pao A, Tang M, Pfeifer GP.
    Science; 1996 Oct 18; 274(5286):430-2. PubMed ID: 8832894
    [Abstract] [Full Text] [Related]

  • 7. Mutational consequences of replication of M13mp7L2 constructs containing cis-opened benzo[a]pyrene 7,8-diol 9, 10-epoxide-deoxyadenosine adducts.
    Page JE, Pilcher AS, Yagi H, Sayer JM, Jerina DM, Dipple A.
    Chem Res Toxicol; 1999 Mar 18; 12(3):258-63. PubMed ID: 10077488
    [Abstract] [Full Text] [Related]

  • 8. Stereochemical, structural, and thermodynamic origins of stability differences between stereoisomeric benzo[a]pyrene diol epoxide deoxyadenosine adducts in a DNA mutational hot spot sequence.
    Yan S, Shapiro R, Geacintov NE, Broyde S.
    J Am Chem Soc; 2001 Jul 25; 123(29):7054-66. PubMed ID: 11459484
    [Abstract] [Full Text] [Related]

  • 9. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Dong H, Bonala RR, Suzuki N, Johnson F, Grollman AP, Shibutani S.
    Biochemistry; 2004 Dec 21; 43(50):15922-8. PubMed ID: 15595848
    [Abstract] [Full Text] [Related]

  • 10. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
    Yoon JH, Smith LE, Feng Z, Tang M, Lee CS, Pfeifer GP.
    Cancer Res; 2001 Oct 01; 61(19):7110-7. PubMed ID: 11585742
    [Abstract] [Full Text] [Related]

  • 11. Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, 1-nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, and 3-nitrobenzo[a]pyrene trans-7,8- diol-anti-9,10-epoxide.
    Zhan DJ, Heflich RH, Fu PP.
    Environ Mol Mutagen; 1996 Oct 01; 27(1):19-29. PubMed ID: 8625944
    [Abstract] [Full Text] [Related]

  • 12. Preferential carcinogen-DNA adduct formation at codons 12 and 14 in the human K-ras gene and their possible mechanisms.
    Hu W, Feng Z, Tang MS.
    Biochemistry; 2003 Aug 26; 42(33):10012-23. PubMed ID: 12924950
    [Abstract] [Full Text] [Related]

  • 13. Separation and characterization of post-labeled DNA adducts of stereoisomers of benzo[a]pyrene-7,8-diol-9,10-epoxide by immobilized boronate chromatography and HPLC analysis.
    Lau HH, Baird WM.
    Carcinogenesis; 1994 May 26; 15(5):907-15. PubMed ID: 8200094
    [Abstract] [Full Text] [Related]

  • 14. Adduction of the human N-ras codon 61 sequence with (-)-(7S,8R,9R,10S)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a] pyrene: structural refinement of the intercalated SRSR(61,2) (-)-(7S,8R,9S,10R)-N6-[10-(7,8,9,10- tetrahydrobenzo[a]pyrenyl)]-2'-deoxyadenosyl adduct from 1H NMR.
    Zegar IS, Kim SJ, Johansen TN, Horton PJ, Harris CM, Harris TM, Stone MP.
    Biochemistry; 1996 May 21; 35(20):6212-24. PubMed ID: 8639561
    [Abstract] [Full Text] [Related]

  • 15. TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.
    Kucab JE, van Steeg H, Luijten M, Schmeiser HH, White PA, Phillips DH, Arlt VM.
    Mutat Res; 2015 Mar 21; 773():48-62. PubMed ID: 25847421
    [Abstract] [Full Text] [Related]

  • 16. Solution structure of the minor conformer of a DNA duplex containing a dG mismatch opposite a benzo[a]pyrene diol epoxide/dA adduct: glycosidic rotation from syn to anti at the modified deoxyadenosine.
    Schwartz JL, Rice JS, Luxon BA, Sayer JM, Xie G, Yeh HJ, Liu X, Jerina DM, Gorenstein DG.
    Biochemistry; 1997 Sep 16; 36(37):11069-76. PubMed ID: 9333324
    [Abstract] [Full Text] [Related]

  • 17. Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.
    Denissenko MF, Pao A, Pfeifer GP, Tang M.
    Oncogene; 1998 Mar 12; 16(10):1241-7. PubMed ID: 9546425
    [Abstract] [Full Text] [Related]

  • 18. Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.
    Perlow RA, Broyde S.
    J Mol Biol; 2001 Jun 01; 309(2):519-36. PubMed ID: 11371169
    [Abstract] [Full Text] [Related]

  • 19. Mutagenic potential of stereoisomeric bay region (+)- and (-)-cis-anti-benzo[a]pyrene diol epoxide-N2-2'-deoxyguanosine adducts in Escherichia coli and simian kidney cells.
    Fernandes A, Liu T, Amin S, Geacintov NE, Grollman AP, Moriya M.
    Biochemistry; 1998 Jul 14; 37(28):10164-72. PubMed ID: 9665722
    [Abstract] [Full Text] [Related]

  • 20. Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung.
    Hussain SP, Amstad P, Raja K, Sawyer M, Hofseth L, Shields PG, Hewer A, Phillips DH, Ryberg D, Haugen A, Harris CC.
    Cancer Res; 2001 Sep 01; 61(17):6350-5. PubMed ID: 11522624
    [Abstract] [Full Text] [Related]

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