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Journal Abstract Search

299 related items for PubMed ID: 10715155

  • 1. Structure-based design of potent, amidine-derived inhibitors of factor Xa: evaluation of selectivity, anticoagulant activity, and antithrombotic activity.
    Wiley MR, Weir LC, Briggs S, Bryan NA, Buben J, Campbell C, Chirgadze NY, Conrad RC, Craft TJ, Ficorilli JV, Franciskovich JB, Froelich LL, Gifford-Moore DS, Goodson T, Herron DK, Klimkowski VJ, Kurz KD, Kyle JA, Masters JJ, Ratz AM, Milot G, Shuman RT, Smith T, Smith GF, Tebbe AL, Tinsley JM.
    J Med Chem; 2000 Mar 09; 43(5):883-99. PubMed ID: 10715155
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  • 3. 1,2-Dibenzamidobenzene inhibitors of human factor Xa.
    Herron DK, Goodson T, Wiley MR, Weir LC, Kyle JA, Yee YK, Tebbe AL, Tinsley JM, Mendel D, Masters JJ, Franciskovich JB, Sawyer JS, Beight DW, Ratz AM, Milot G, Hall SE, Klimkowski VJ, Wikel JH, Eastwood BJ, Towner RD, Gifford-Moore DS, Craft TJ, Smith GF.
    J Med Chem; 2000 Mar 09; 43(5):859-72. PubMed ID: 10715153
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  • 4. In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
    Costanzo MJ, Almond HR, Hecker LR, Schott MR, Yabut SC, Zhang HC, Andrade-Gordon P, Corcoran TW, Giardino EC, Kauffman JA, Lewis JM, de Garavilla L, Haertlein BJ, Maryanoff BE.
    J Med Chem; 2005 Mar 24; 48(6):1984-2008. PubMed ID: 15771442
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  • 6. Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors.
    Han Q, Dominguez C, Stouten PF, Park JM, Duffy DE, Galemmo RA, Rossi KA, Alexander RS, Smallwood AM, Wong PC, Wright MM, Luettgen JM, Knabb RM, Wexler RR.
    J Med Chem; 2000 Nov 16; 43(23):4398-415. PubMed ID: 11087565
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  • 9. Discovery of the factor Xa inhibitor, ZK 807834 (CI-1031).
    Light DR, Guilford WJ.
    Curr Top Med Chem; 2001 Jun 16; 1(2):121-36. PubMed ID: 11899248
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  • 10. N(2)-Aroylanthranilamide inhibitors of human factor Xa.
    Yee YK, Tebbe AL, Linebarger JH, Beight DW, Craft TJ, Gifford-Moore D, Goodson T, Herron DK, Klimkowski VJ, Kyle JA, Sawyer JS, Smith GF, Tinsley JM, Towner RD, Weir L, Wiley MR.
    J Med Chem; 2000 Mar 09; 43(5):873-82. PubMed ID: 10715154
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  • 14. Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa.
    Ewing WR, Becker MR, Manetta VE, Davis RS, Pauls HW, Mason H, Choi-Sledeski YM, Green D, Cha D, Spada AP, Cheney DL, Mason JS, Maignan S, Guilloteau JP, Brown K, Colussi D, Bentley R, Bostwick J, Kasiewski CJ, Morgan SR, Leadley RJ, Dunwiddie CT, Perrone MH, Chu V.
    J Med Chem; 1999 Sep 09; 42(18):3557-71. PubMed ID: 10479288
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  • 15. New series of 6-substituted coumarin derivatives as effective factor Xa inhibitors: synthesis, in vivo antithrombotic evaluation and molecular docking.
    Amin KM, Abdel Gawad NM, Abdel Rahman DE, El Ashry MK.
    Bioorg Chem; 2014 Feb 09; 52():31-43. PubMed ID: 24316885
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  • 18. Design, synthesis, and activity of 2,6-diphenoxypyridine-derived factor Xa inhibitors.
    Phillips G, Davey DD, Eagen KA, Koovakkat SK, Liang A, Ng HP, Pinkerton M, Trinh L, Whitlow M, Beatty AM, Morrissey MM.
    J Med Chem; 1999 May 20; 42(10):1749-56. PubMed ID: 10346927
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  • 19. Sulfonamidopyrrolidinone factor Xa inhibitors: potency and selectivity enhancements via P-1 and P-4 optimization.
    Choi-Sledeski YM, McGarry DG, Green DM, Mason HJ, Becker MR, Davis RS, Ewing WR, Dankulich WP, Manetta VE, Morris RL, Spada AP, Cheney DL, Brown KD, Colussi DJ, Chu V, Heran CL, Morgan SR, Bentley RG, Leadley RJ, Maignan S, Guilloteau JP, Dunwiddie CT, Pauls HW.
    J Med Chem; 1999 Sep 09; 42(18):3572-87. PubMed ID: 10479289
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