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Journal Abstract Search


221 related items for PubMed ID: 10716194

  • 1. Cleaved antitrypsin polymers at atomic resolution.
    Dunstone MA, Dai W, Whisstock JC, Rossjohn J, Pike RN, Feil SC, Le Bonniec BF, Parker MW, Bottomley SP.
    Protein Sci; 2000 Feb; 9(2):417-20. PubMed ID: 10716194
    [Abstract] [Full Text] [Related]

  • 2. A 2.6 A structure of a serpin polymer and implications for conformational disease.
    Huntington JA, Pannu NS, Hazes B, Read RJ, Lomas DA, Carrell RW.
    J Mol Biol; 1999 Oct 29; 293(3):449-55. PubMed ID: 10543942
    [Abstract] [Full Text] [Related]

  • 3. Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation.
    Elliott PR, Abrahams JP, Lomas DA.
    J Mol Biol; 1998 Jan 23; 275(3):419-25. PubMed ID: 9466920
    [Abstract] [Full Text] [Related]

  • 4. Lung polymers in Z alpha1-antitrypsin deficiency-related emphysema.
    Elliott PR, Bilton D, Lomas DA.
    Am J Respir Cell Mol Biol; 1998 May 23; 18(5):670-4. PubMed ID: 9569237
    [Abstract] [Full Text] [Related]

  • 5. Hypersensitive mousetraps, alpha1-antitrypsin deficiency and dementia.
    Lomas DA, Lourbakos A, Cumming SA, Belorgey D.
    Biochem Soc Trans; 2002 Apr 23; 30(2):89-92. PubMed ID: 12023831
    [Abstract] [Full Text] [Related]

  • 6. The mechanism of alpha 1-antitrypsin polymerization probed by fluorescence spectroscopy.
    James EL, Bottomley SP.
    Arch Biochem Biophys; 1998 Aug 15; 356(2):296-300. PubMed ID: 9705220
    [Abstract] [Full Text] [Related]

  • 7. Alpha 1-antitrypsin polymerisation can occur by both loop A and C sheet mechanisms.
    Bottomley SP, Hopkins PC, Whisstock JC.
    Biochem Biophys Res Commun; 1998 Oct 09; 251(1):1-5. PubMed ID: 9790897
    [Abstract] [Full Text] [Related]

  • 8. A 2.1 A resolution structure of an uncleaved alpha(1)-antitrypsin shows variability of the reactive center and other loops.
    Kim S, Woo J, Seo EJ, Yu M, Ryu S.
    J Mol Biol; 2001 Feb 09; 306(1):109-19. PubMed ID: 11178897
    [Abstract] [Full Text] [Related]

  • 9. Alpha1-antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy.
    Lomas DA, Mahadeva R.
    J Clin Invest; 2002 Dec 09; 110(11):1585-90. PubMed ID: 12464660
    [No Abstract] [Full Text] [Related]

  • 10. The mechanism of Z alpha 1-antitrypsin accumulation in the liver.
    Lomas DA, Evans DL, Finch JT, Carrell RW.
    Nature; 1992 Jun 18; 357(6379):605-7. PubMed ID: 1608473
    [Abstract] [Full Text] [Related]

  • 11. Characterization and suppression of dysfunctional human alpha1-antitrypsin variants.
    Kim MJ, Jung CH, Im H.
    Biochem Biophys Res Commun; 2006 Apr 28; 343(1):295-302. PubMed ID: 16540089
    [Abstract] [Full Text] [Related]

  • 12. The effect of the Glu342Lys mutation in alpha1-antitrypsin on its structure, studied by molecular modelling methods.
    Jezierski G, Pasenkiewicz-Gierula M.
    Acta Biochim Pol; 2001 Apr 28; 48(1):65-75. PubMed ID: 11440184
    [Abstract] [Full Text] [Related]

  • 13. Probing the local conformational change of alpha1-antitrypsin.
    Baek JH, Im H, Kang UB, Seong KM, Lee C, Kim J, Yu MH.
    Protein Sci; 2007 Sep 28; 16(9):1842-50. PubMed ID: 17660256
    [Abstract] [Full Text] [Related]

  • 14. Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.
    Whisstock JC, Skinner R, Carrell RW, Lesk AM.
    J Mol Biol; 2000 Jan 21; 295(3):651-65. PubMed ID: 10623554
    [Abstract] [Full Text] [Related]

  • 15. Dimers initiate and propagate serine protease inhibitor polymerisation.
    Zhou A, Carrell RW.
    J Mol Biol; 2008 Jan 04; 375(1):36-42. PubMed ID: 18005992
    [Abstract] [Full Text] [Related]

  • 16. Molecular Mechanism of Z α1-Antitrypsin Deficiency.
    Huang X, Zheng Y, Zhang F, Wei Z, Wang Y, Carrell RW, Read RJ, Chen GQ, Zhou A.
    J Biol Chem; 2016 Jul 22; 291(30):15674-86. PubMed ID: 27246852
    [Abstract] [Full Text] [Related]

  • 17. Molecular pathogenesis of liver disease in alpha1-antitrypsin deficiency.
    Teckman JH, Qu D, Perlmutter DH.
    Hepatology; 1996 Dec 22; 24(6):1504-16. PubMed ID: 8938188
    [No Abstract] [Full Text] [Related]

  • 18. Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of alpha1-antitrypsin.
    Janciauskiene S, Eriksson S, Callea F, Mallya M, Zhou A, Seyama K, Hata S, Lomas DA.
    Hepatology; 2004 Nov 22; 40(5):1203-10. PubMed ID: 15486938
    [Abstract] [Full Text] [Related]

  • 19. Serpin polymerization and its role in disease--the molecular basis of alpha1-antitrypsin deficiency.
    Knaupp AS, Bottomley SP.
    IUBMB Life; 2009 Jan 22; 61(1):1-5. PubMed ID: 18785256
    [Abstract] [Full Text] [Related]

  • 20. Bypassing the kinetic trap of serpin protein folding by loop extension.
    Im H, Ahn HY, Yu MH.
    Protein Sci; 2000 Aug 22; 9(8):1497-502. PubMed ID: 10975571
    [Abstract] [Full Text] [Related]


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