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205 related items for PubMed ID: 10728688

  • 1. The food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates S-phase checkpoint and apoptosis, and induces gene mutation in human lymphoblastoid TK6 cells.
    Zhu H, Boobis AR, Gooderham NJ.
    Cancer Res; 2000 Mar 01; 60(5):1283-9. PubMed ID: 10728688
    [Abstract] [Full Text] [Related]

  • 2. The effect of UDP-glucuronosyltransferase 1A1 expression on the mutagenicity and metabolism of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in CHO cells.
    Malfatti MA, Wu RW, Felton JS.
    Mutat Res; 2005 Mar 01; 570(2):205-14. PubMed ID: 15708579
    [Abstract] [Full Text] [Related]

  • 3. The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells.
    Vanhaecke L, Derycke L, Le Curieux F, Lust S, Marzin D, Verstraete W, Bracke M.
    Toxicol Lett; 2008 Apr 21; 178(1):61-9. PubMed ID: 18375078
    [Abstract] [Full Text] [Related]

  • 4. A mechanistic basis for the role of cycle arrest in the genetic toxicology of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
    Creton S, Zhu H, Gooderham NJ.
    Toxicol Sci; 2005 Apr 21; 84(2):335-43. PubMed ID: 15635149
    [Abstract] [Full Text] [Related]

  • 5. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.
    Nelson CP, Kidd LC, Sauvageot J, Isaacs WB, De Marzo AM, Groopman JD, Nelson WG, Kensler TW.
    Cancer Res; 2001 Jan 01; 61(1):103-9. PubMed ID: 11196146
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of cell death in human mammary epithelial cells by the cooked meat-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine.
    Venugopal M, Agarwal R, Callaway A, Schut HA, Snyderwine EG.
    Biochem Biophys Res Commun; 1999 Dec 09; 266(1):203-7. PubMed ID: 10581190
    [Abstract] [Full Text] [Related]

  • 7. Mutational spectra of the dietary carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine(PhIP) at the Chinese hamsters hprt locus.
    Yadollahi-Farsani M, Gooderham NJ, Davies DS, Boobis AR.
    Carcinogenesis; 1996 Apr 09; 17(4):617-24. PubMed ID: 8625468
    [Abstract] [Full Text] [Related]

  • 8. Specificity of mutations induced by the food-associated heterocyclic amine 2-amino-1-methyl-6-phenylimidazo-[4,5-b]-pyridine in colon cancer cell lines defective in mismatch repair.
    Glaab WE, Kort KL, Skopek TR.
    Cancer Res; 2000 Sep 01; 60(17):4921-5. PubMed ID: 10987307
    [Abstract] [Full Text] [Related]

  • 9. The cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates the extracellular signal regulated kinase mitogen-activated protein kinase pathway.
    Creton SK, Zhu H, Gooderham NJ.
    Cancer Res; 2007 Dec 01; 67(23):11455-62. PubMed ID: 18056474
    [Abstract] [Full Text] [Related]

  • 10. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induces genetic changes in murine intestinal tumours and cells with ApcMin mutation.
    Andreassen A, Vikse R, Mikalsen A, Adamovic T, Steffensen IL, Hjertholm H, Levan G, Alexander J.
    Mutat Res; 2006 Apr 30; 604(1-2):60-70. PubMed ID: 16574467
    [Abstract] [Full Text] [Related]

  • 11. Development of apoptosis and polyploidy in human lymphoblast cells as a function of position in the cell cycle at the time of irradiation.
    Olive PL, Banáth JP, Durand RE.
    Radiat Res; 1996 Dec 30; 146(6):595-602. PubMed ID: 8955708
    [Abstract] [Full Text] [Related]

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  • 13. Relationships between genomic, cell cycle, and mutagenic responses of TK6 cells exposed to DNA damaging chemicals.
    Islaih M, Halstead BW, Kadura IA, Li B, Reid-Hubbard JL, Flick L, Altizer JL, Thom Deahl J, Monteith DK, Newton RK, Watson DE.
    Mutat Res; 2005 Oct 15; 578(1-2):100-16. PubMed ID: 16109433
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  • 15. Age at exposure and Apc status influence the levels of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in mouse intestine and liver.
    Steffensen IL, Schut HA, Alexander J.
    Mutat Res; 2005 Nov 10; 587(1-2):73-89. PubMed ID: 16202642
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  • 17. Mutagenicity of food-derived carcinogens and the effect of antioxidant vitamins.
    Montgomery BA, Murphy J, Chen JJ, Desai VG, McGarrity L, Morris SM, Casciano DA, Aidoo A.
    Nutr Cancer; 2002 Nov 10; 43(1):103-10. PubMed ID: 12467141
    [Abstract] [Full Text] [Related]

  • 18. The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity.
    Lauber SN, Ali S, Gooderham NJ.
    Carcinogenesis; 2004 Dec 10; 25(12):2509-17. PubMed ID: 15319301
    [Abstract] [Full Text] [Related]

  • 19. The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine promotes invasive behaviour of breast cancer cells.
    Lauber SN, Gooderham NJ.
    Toxicology; 2011 Jan 11; 279(1-3):139-45. PubMed ID: 20951759
    [Abstract] [Full Text] [Related]

  • 20. Role of p53 and mismatch repair in PhIP-induced perturbations of the cell cycle.
    Duc R, Leong-Morgenthaler PM.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2004 Mar 25; 802(1):183-7. PubMed ID: 15036010
    [Abstract] [Full Text] [Related]

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