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674 related items for PubMed ID: 10741717

  • 1. Flavopiridol, a cyclin-dependent kinase inhibitor, prevents spindle inhibitor-induced endoreduplication in human cancer cells.
    Motwani M, Li X, Schwartz GK.
    Clin Cancer Res; 2000 Mar; 6(3):924-32. PubMed ID: 10741717
    [Abstract] [Full Text] [Related]

  • 2. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.
    Carlson BA, Dubay MM, Sausville EA, Brizuela L, Worland PJ.
    Cancer Res; 1996 Jul 01; 56(13):2973-8. PubMed ID: 8674031
    [Abstract] [Full Text] [Related]

  • 3. p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption.
    Stewart ZA, Leach SD, Pietenpol JA.
    Mol Cell Biol; 1999 Jan 01; 19(1):205-15. PubMed ID: 9858545
    [Abstract] [Full Text] [Related]

  • 4. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
    Yin MB, Guo B, Panadero A, Frank C, Wrzosek C, Slocum HK, Rustum YM.
    Exp Cell Res; 1999 Feb 25; 247(1):189-99. PubMed ID: 10047461
    [Abstract] [Full Text] [Related]

  • 5. Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis.
    Patel V, Senderowicz AM, Pinto D, Igishi T, Raffeld M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS.
    J Clin Invest; 1998 Nov 01; 102(9):1674-81. PubMed ID: 9802881
    [Abstract] [Full Text] [Related]

  • 6. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S, Lowe M, Herliczek TW, Keyomarsi K.
    Oncogene; 1998 Nov 05; 17(18):2393-402. PubMed ID: 9811471
    [Abstract] [Full Text] [Related]

  • 7. Selective sensitization of retinoblastoma protein-deficient sarcoma cells to doxorubicin by flavopiridol-mediated inhibition of cyclin-dependent kinase 2 kinase activity.
    Li W, Fan J, Bertino JR.
    Cancer Res; 2001 Mar 15; 61(6):2579-82. PubMed ID: 11289134
    [Abstract] [Full Text] [Related]

  • 8. Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints.
    Xie G, Habbersett RC, Jia Y, Peterson SR, Lehnert BE, Bradbury EM, D'Anna JA.
    Oncogene; 1998 Feb 12; 16(6):721-36. PubMed ID: 9488036
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
    Coppock DL, Buffolino P, Kopman C, Nathanson L.
    Exp Cell Res; 1995 Nov 12; 221(1):92-102. PubMed ID: 7589260
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate.
    Liang YC, Lin-Shiau SY, Chen CF, Lin JK.
    J Cell Biochem; 1999 Oct 01; 75(1):1-12. PubMed ID: 10462699
    [Abstract] [Full Text] [Related]

  • 11. Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.
    Damiens E, El Yazidi I, Mazurier J, Duthille I, Spik G, Boilly-Marer Y.
    J Cell Biochem; 1999 Sep 01; 74(3):486-98. PubMed ID: 10412049
    [Abstract] [Full Text] [Related]

  • 12. Sequential dependent enhancement of caspase activation and apoptosis by flavopiridol on paclitaxel-treated human gastric and breast cancer cells.
    Motwani M, Delohery TM, Schwartz GK.
    Clin Cancer Res; 1999 Jul 01; 5(7):1876-83. PubMed ID: 10430095
    [Abstract] [Full Text] [Related]

  • 13. CaMK-II inhibition reduces cyclin D1 levels and enhances the association of p27kip1 with Cdk2 to cause G1 arrest in NIH 3T3 cells.
    Morris TA, DeLorenzo RJ, Tombes RM.
    Exp Cell Res; 1998 May 01; 240(2):218-27. PubMed ID: 9596994
    [Abstract] [Full Text] [Related]

  • 14. F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation.
    Malashicheva AB, Kislyakova TV, Aksenov ND, Osipov KA, Pospelov VA.
    Oncogene; 2000 Aug 10; 19(34):3858-65. PubMed ID: 10951579
    [Abstract] [Full Text] [Related]

  • 15. Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells.
    Sandhu C, Donovan J, Bhattacharya N, Stampfer M, Worland P, Slingerland J.
    Oncogene; 2000 Nov 09; 19(47):5314-23. PubMed ID: 11103932
    [Abstract] [Full Text] [Related]

  • 16. Induction of p53-independent p21 during ceramide-induced G1 arrest in human hepatocarcinoma cells.
    Kim WH, Kang KH, Kim MY, Choi KH.
    Biochem Cell Biol; 2000 Nov 09; 78(2):127-35. PubMed ID: 10874474
    [Abstract] [Full Text] [Related]

  • 17. Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol.
    Carlson B, Lahusen T, Singh S, Loaiza-Perez A, Worland PJ, Pestell R, Albanese C, Sausville EA, Senderowicz AM.
    Cancer Res; 1999 Sep 15; 59(18):4634-41. PubMed ID: 10493518
    [Abstract] [Full Text] [Related]

  • 18. Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein.
    Reshetnikova G, Barkan R, Popov B, Nikolsky N, Chang LS.
    Exp Cell Res; 2000 Aug 25; 259(1):35-53. PubMed ID: 10942577
    [Abstract] [Full Text] [Related]

  • 19. p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases.
    Medema RH, Klompmaker R, Smits VA, Rijksen G.
    Oncogene; 1998 Jan 29; 16(4):431-41. PubMed ID: 9484832
    [Abstract] [Full Text] [Related]

  • 20. Hyperoxia induces S-phase cell-cycle arrest and p21(Cip1/Waf1)-independent Cdk2 inhibition in human carcinoma T47D-H3 cells.
    Bilodeau JF, Faure R, Piedboeuf B, Mirault ME.
    Exp Cell Res; 2000 May 01; 256(2):347-57. PubMed ID: 10772807
    [Abstract] [Full Text] [Related]


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