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PUBMED FOR HANDHELDS

Journal Abstract Search


136 related items for PubMed ID: 10743956

  • 1. Bifunctional alkylating agents derived from duocarmycin SA: potent antitumor activity with altered sequence selectivity.
    Boger DL, Searcey M, Tse WC, Jin Q.
    Bioorg Med Chem Lett; 2000 Mar 06; 10(5):495-8. PubMed ID: 10743956
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  • 4. Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders.
    Baraldi PG, Balboni G, Pavani MG, Spalluto G, Tabrizi MA, Clercq ED, Balzarini J, Bando T, Sugiyama H, Romagnoli R.
    J Med Chem; 2001 Aug 02; 44(16):2536-43. PubMed ID: 11472207
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  • 5. Alkylation of duplex DNA in nucleosome core particles by duocarmycin SA and yatakemycin.
    Trzupek JD, Gottesfeld JM, Boger DL.
    Nat Chem Biol; 2006 Feb 02; 2(2):79-82. PubMed ID: 16415862
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  • 9. Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation.
    Lajiness JP, Robertson WM, Dunwiddie I, Broward MA, Vielhauer GA, Weir SJ, Boger DL.
    J Med Chem; 2010 Nov 11; 53(21):7731-8. PubMed ID: 20942408
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  • 12. Total synthesis and evaluation of iso-duocarmycin SA and iso-yatakemycin.
    MacMillan KS, Nguyen T, Hwang I, Boger DL.
    J Am Chem Soc; 2009 Jan 28; 131(3):1187-94. PubMed ID: 19154178
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  • 17. Asymmetric total synthesis of (+)- and ent-(-)-yatakemycin and duocarmycin SA: evaluation of yatakemycin key partial structures and its unnatural enantiomer.
    Tichenor MS, Trzupek JD, Kastrinsky DB, Shiga F, Hwang I, Boger DL.
    J Am Chem Soc; 2006 Dec 13; 128(49):15683-96. PubMed ID: 17147378
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  • 20. Sequence-specific alkylation by a tandem motif of pyrrole-imidazole CBI conjugate.
    Sasaki S, Minoshima M, Fujimoto J, Shinohara K, Bando T, Sugiyama H.
    Nucleic Acids Symp Ser (Oxf); 2007 Dec 13; (51):265-6. PubMed ID: 18029688
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