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463 related items for PubMed ID: 10744652

  • 1. The CD45 tyrosine phosphatase regulates Campath-1H (CD52)-induced TCR-dependent signal transduction in human T cells.
    Hederer RA, Guntermann C, Miller N, Nagy P, Szollosi J, Damjanovich S, Hale G, Alexander DR.
    Int Immunol; 2000 Apr; 12(4):505-16. PubMed ID: 10744652
    [Abstract] [Full Text] [Related]

  • 2. Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes.
    Rowan WC, Hale G, Tite JP, Brett SJ.
    Int Immunol; 1995 Jan; 7(1):69-77. PubMed ID: 7718516
    [Abstract] [Full Text] [Related]

  • 3. CD45 modulates T cell receptor/CD3-induced activation of human thymocytes via regulation of tyrosine phosphorylation.
    Turka LA, Kanner SB, Schieven GL, Thompson CB, Ledbetter JA.
    Eur J Immunol; 1992 Feb; 22(2):551-7. PubMed ID: 1371471
    [Abstract] [Full Text] [Related]

  • 4. Interaction of CD4:lck with the T cell receptor/CD3 complex induces early signaling events in the absence of CD45 tyrosine phosphatase.
    Deans JP, Kanner SB, Torres RM, Ledbetter JA.
    Eur J Immunol; 1992 Mar; 22(3):661-8. PubMed ID: 1532148
    [Abstract] [Full Text] [Related]

  • 5. Surface expression of hemopoietic cell phosphatase fails to complement CD45 deficiency and inhibits TCR-mediated signal transduction in a Jurkat T cell clone.
    Musci MA, Beaves SL, Ross SE, Yi T, Koretzky GA.
    J Immunol; 1997 Feb 15; 158(4):1565-71. PubMed ID: 9029091
    [Abstract] [Full Text] [Related]

  • 6. Does co-aggregation of the CD45 and CD3 antigens inhibit T cell antigen receptor complex-mediated activation of phospholipase C and protein kinase C?
    Shivnan E, Biffen M, Shiroo M, Pratt E, Glennie M, Alexander D.
    Eur J Immunol; 1992 Apr 15; 22(4):1055-62. PubMed ID: 1532359
    [Abstract] [Full Text] [Related]

  • 7. Cross-linking of the CAMPATH-1 antigen (CD52) mediates growth inhibition in human B- and T-lymphoma cell lines, and subsequent emergence of CD52-deficient cells.
    Rowan W, Tite J, Topley P, Brett SJ.
    Immunology; 1998 Nov 15; 95(3):427-36. PubMed ID: 9824507
    [Abstract] [Full Text] [Related]

  • 8. Impact on T-cell depletion and CD34+ cell recovery using humanised CD52 monoclonal antibody (CAMPATH-1H) in BM and PSBC collections; comparison with CAMPATH-1M and CAMPATH-1G.
    Williams RJ, Clarke E, Blair A, Evely R, Hale G, Waldmann H, Brookes S, Pamphilon DH.
    Cytotherapy; 2000 Nov 15; 2(1):5-14. PubMed ID: 12042050
    [Abstract] [Full Text] [Related]

  • 9. Emergence of CD52-, glycosylphosphatidylinositol-anchor-deficient lymphocytes in rheumatoid arthritis patients following Campath-1H treatment.
    Brett SJ, Baxter G, Cooper H, Rowan W, Regan T, Tite J, Rapson N.
    Int Immunol; 1996 Mar 15; 8(3):325-34. PubMed ID: 8671618
    [Abstract] [Full Text] [Related]

  • 10. Restoration of T cell receptor-mediated signal transduction by transfection of CD45 cDNA into a CD45-deficient variant of the Jurkat T cell line.
    Koretzky GA, Kohmetscher MA, Kadleck T, Weiss A.
    J Immunol; 1992 Aug 15; 149(4):1138-42. PubMed ID: 1380033
    [Abstract] [Full Text] [Related]

  • 11. Effective therapy for a murine model of adult T-cell leukemia with the humanized anti-CD52 monoclonal antibody, Campath-1H.
    Zhang Z, Zhang M, Goldman CK, Ravetch JV, Waldmann TA.
    Cancer Res; 2003 Oct 01; 63(19):6453-7. PubMed ID: 14559836
    [Abstract] [Full Text] [Related]

  • 12. Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70.
    Stone JD, Conroy LA, Byth KF, Hederer RA, Howlett S, Takemoto Y, Holmes N, Alexander DR.
    J Immunol; 1997 Jun 15; 158(12):5773-82. PubMed ID: 9190928
    [Abstract] [Full Text] [Related]

  • 13. CD45 monoclonal antibodies inhibit TCR-mediated calcium signals, calmodulin-kinase IV/Gr activation, and oncoprotein 18 phosphorylation.
    Shivnan E, Clayton L, Allridge L, Keating KE, Gullberg M, Alexander DR.
    J Immunol; 1996 Jul 01; 157(1):101-9. PubMed ID: 8683102
    [Abstract] [Full Text] [Related]

  • 14. CD45 cross-linking regulates phospholipase C activation and tyrosine phosphorylation of specific substrates in CD3/Ti-stimulated T cells.
    Ledbetter JA, Schieven GL, Uckun FM, Imboden JB.
    J Immunol; 1991 Mar 01; 146(5):1577-83. PubMed ID: 1847166
    [Abstract] [Full Text] [Related]

  • 15. CD45 tyrosine phosphatase-activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influx.
    Shiroo M, Goff L, Biffen M, Shivnan E, Alexander D.
    EMBO J; 1992 Dec 01; 11(13):4887-97. PubMed ID: 1464315
    [Abstract] [Full Text] [Related]

  • 16. The CD45 protein tyrosine phosphatase is required for the completion of the activation program leading to lymphokine production in the Jurkat human T cell line.
    Peyron JF, Verma S, de Waal Malefyt R, Sancho J, Terhorst C, Spits H.
    Int Immunol; 1991 Dec 01; 3(12):1357-66. PubMed ID: 1838006
    [Abstract] [Full Text] [Related]

  • 17. Levels of expression of CD52 in normal and leukemic B and T cells: correlation with in vivo therapeutic responses to Campath-1H.
    Ginaldi L, De Martinis M, Matutes E, Farahat N, Morilla R, Dyer MJ, Catovsky D.
    Leuk Res; 1998 Feb 01; 22(2):185-91. PubMed ID: 9593475
    [Abstract] [Full Text] [Related]

  • 18. Clonal CD8+ and CD52- T cells are induced in responding B cell lymphoma patients treated with Campath-1H (anti-CD52).
    Osterborg A, Werner A, Halapi E, Lundin J, Harmenberg U, Wigzell H, Mellstedt H.
    Eur J Haematol; 1997 Jan 01; 58(1):5-13. PubMed ID: 9020367
    [Abstract] [Full Text] [Related]

  • 19. Regulation of CD3-induced phospholipase C-gamma 1 (PLC gamma 1) tyrosine phosphorylation by CD4 and CD45 receptors.
    Kanner SB, Deans JP, Ledbetter JA.
    Immunology; 1992 Mar 01; 75(3):441-7. PubMed ID: 1533389
    [Abstract] [Full Text] [Related]

  • 20. The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.
    Biffen M, McMichael-Phillips D, Larson T, Venkitaraman A, Alexander D.
    EMBO J; 1994 Apr 15; 13(8):1920-9. PubMed ID: 8168490
    [Abstract] [Full Text] [Related]

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