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Journal Abstract Search

341 related items for PubMed ID: 10744722

  • 1. Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity.
    Zhou BB, Chaturvedi P, Spring K, Scott SP, Johanson RA, Mishra R, Mattern MR, Winkler JD, Khanna KK.
    J Biol Chem; 2000 Apr 07; 275(14):10342-8. PubMed ID: 10744722
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  • 2. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway.
    Chaturvedi P, Eng WK, Zhu Y, Mattern MR, Mishra R, Hurle MR, Zhang X, Annan RS, Lu Q, Faucette LF, Scott GF, Li X, Carr SA, Johnson RK, Winkler JD, Zhou BB.
    Oncogene; 1999 Jul 15; 18(28):4047-54. PubMed ID: 10435585
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  • 3. Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
    Agarwal C, Tyagi A, Agarwal R.
    Mol Cancer Ther; 2006 Dec 15; 5(12):3294-302. PubMed ID: 17172433
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  • 6. The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01.
    Graves PR, Yu L, Schwarz JK, Gales J, Sausville EA, O'Connor PM, Piwnica-Worms H.
    J Biol Chem; 2000 Feb 25; 275(8):5600-5. PubMed ID: 10681541
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  • 9. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
    Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R.
    Carcinogenesis; 2005 Nov 25; 26(11):1978-87. PubMed ID: 15975956
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  • 10. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.
    Falck J, Mailand N, Syljuåsen RG, Bartek J, Lukas J.
    Nature; 2001 Apr 12; 410(6830):842-7. PubMed ID: 11298456
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  • 11. Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2.
    Carlessi L, Buscemi G, Larson G, Hong Z, Wu JZ, Delia D.
    Mol Cancer Ther; 2007 Mar 12; 6(3):935-44. PubMed ID: 17363488
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  • 12. Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.
    Singh SV, Herman-Antosiewicz A, Singh AV, Lew KL, Srivastava SK, Kamath R, Brown KD, Zhang L, Baskaran R.
    J Biol Chem; 2004 Jun 11; 279(24):25813-22. PubMed ID: 15073169
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  • 13. Chk2 activation dependence on Nbs1 after DNA damage.
    Buscemi G, Savio C, Zannini L, Miccichè F, Masnada D, Nakanishi M, Tauchi H, Komatsu K, Mizutani S, Khanna K, Chen P, Concannon P, Chessa L, Delia D.
    Mol Cell Biol; 2001 Aug 11; 21(15):5214-22. PubMed ID: 11438675
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  • 16. Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases.
    Cortez D.
    J Biol Chem; 2003 Sep 26; 278(39):37139-45. PubMed ID: 12847089
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  • 19. Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1.
    Chang KL, Kung ML, Chow NH, Su SJ.
    Biochem Pharmacol; 2004 Feb 15; 67(4):717-26. PubMed ID: 14757171
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  • 20. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.
    Ouyang G, Yao L, Ruan K, Song G, Mao Y, Bao S.
    Cell Biol Int; 2009 Dec 15; 33(12):1237-44. PubMed ID: 19732843
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