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Journal Abstract Search


210 related items for PubMed ID: 10748157

  • 1. Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase.
    Wu Y, Dowbenko D, Spencer S, Laura R, Lee J, Gu Q, Lasky LA.
    J Biol Chem; 2000 Jul 14; 275(28):21477-85. PubMed ID: 10748157
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  • 2. Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2.
    Wu X, Hepner K, Castelino-Prabhu S, Do D, Kaye MB, Yuan XJ, Wood J, Ross C, Sawyers CL, Whang YE.
    Proc Natl Acad Sci U S A; 2000 Apr 11; 97(8):4233-8. PubMed ID: 10760291
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  • 3. Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.
    Valiente M, Andrés-Pons A, Gomar B, Torres J, Gil A, Tapparel C, Antonarakis SE, Pulido R.
    J Biol Chem; 2005 Aug 12; 280(32):28936-43. PubMed ID: 15951562
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  • 8. Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex.
    Vazquez F, Grossman SR, Takahashi Y, Rokas MV, Nakamura N, Sellers WR.
    J Biol Chem; 2001 Dec 28; 276(52):48627-30. PubMed ID: 11707428
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  • 9. In vivo gene therapy of human bladder cancer with PTEN suppresses tumor growth, downregulates phosphorylated Akt, and increases sensitivity to doxorubicin.
    Tanaka M, Grossman HB.
    Gene Ther; 2003 Sep 28; 10(19):1636-42. PubMed ID: 12923562
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  • 12. Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN.
    Davies MA, Koul D, Dhesi H, Berman R, McDonnell TJ, McConkey D, Yung WK, Steck PA.
    Cancer Res; 1999 Jun 01; 59(11):2551-6. PubMed ID: 10363971
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  • 13. Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway.
    Koul D, Yao Y, Abbruzzese JL, Yung WK, Reddy SA.
    J Biol Chem; 2001 Apr 06; 276(14):11402-8. PubMed ID: 11278366
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  • 19. The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region.
    Georgescu MM, Kirsch KH, Akagi T, Shishido T, Hanafusa H.
    Proc Natl Acad Sci U S A; 1999 Aug 31; 96(18):10182-7. PubMed ID: 10468583
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  • 20. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
    Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, Shi Y, Dixon JE, Pandolfi P, Pavletich NP.
    Cell; 1999 Oct 29; 99(3):323-34. PubMed ID: 10555148
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