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138 related items for PubMed ID: 10748169

  • 1. Presenilin 2 interacts with sorcin, a modulator of the ryanodine receptor.
    Pack-Chung E, Meyers MB, Pettingell WP, Moir RD, Brownawell AM, Cheng I, Tanzi RE, Kim TW.
    J Biol Chem; 2000 May 12; 275(19):14440-5. PubMed ID: 10748169
    [Abstract] [Full Text] [Related]

  • 2. Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling.
    Takeda T, Asahi M, Yamaguchi O, Hikoso S, Nakayama H, Kusakari Y, Kawai M, Hongo K, Higuchi Y, Kashiwase K, Watanabe T, Taniike M, Nakai A, Nishida K, Kurihara S, Donoviel DB, Bernstein A, Tomita T, Iwatsubo T, Hori M, Otsu K.
    FASEB J; 2005 Dec 12; 19(14):2069-71. PubMed ID: 16204356
    [Abstract] [Full Text] [Related]

  • 3. Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2.
    Choi EK, Zaidi NF, Miller JS, Crowley AC, Merriam DE, Lilliehook C, Buxbaum JD, Wasco W.
    J Biol Chem; 2001 Jun 01; 276(22):19197-204. PubMed ID: 11278424
    [Abstract] [Full Text] [Related]

  • 4. Structure-function relationships in sorcin, a member of the penta EF-hand family. Interaction of sorcin fragments with the ryanodine receptor and an Escherichia coli model system.
    Zamparelli C, Ilari A, Verzili D, Giangiacomo L, Colotti G, Pascarella S, Chiancone E.
    Biochemistry; 2000 Feb 01; 39(4):658-66. PubMed ID: 10651630
    [Abstract] [Full Text] [Related]

  • 5. The W105G and W99G sorcin mutants demonstrate the role of the D helix in the Ca(2+)-dependent interaction with annexin VII and the cardiac ryanodine receptor.
    Colotti G, Zamparelli C, Verzili D, Mella M, Loughrey CM, Smith GL, Chiancone E.
    Biochemistry; 2006 Oct 17; 45(41):12519-29. PubMed ID: 17029407
    [Abstract] [Full Text] [Related]

  • 6. Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease.
    Mathews PM, Cataldo AM, Kao BH, Rudnicki AG, Qin X, Yang JL, Jiang Y, Picciano M, Hulette C, Lippa CF, Bird TD, Nochlin D, Walter J, Haass C, Lévesque L, Fraser PE, Andreadis A, Nixon RA.
    Mol Med; 2000 Oct 17; 6(10):878-91. PubMed ID: 11126202
    [Abstract] [Full Text] [Related]

  • 7. Association of sorcin with the cardiac ryanodine receptor.
    Meyers MB, Pickel VM, Sheu SS, Sharma VK, Scotto KW, Fishman GI.
    J Biol Chem; 1995 Nov 03; 270(44):26411-8. PubMed ID: 7592856
    [Abstract] [Full Text] [Related]

  • 8. Alzheimer's disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein.
    Tanahashi H, Tabira T.
    Hum Mol Genet; 2000 Sep 22; 9(15):2281-9. PubMed ID: 11001931
    [Abstract] [Full Text] [Related]

  • 9. The N-terminus of presenilin-2 increases single channel activity of brain ryanodine receptors through direct protein-protein interaction.
    Hayrapetyan V, Rybalchenko V, Rybalchenko N, Koulen P.
    Cell Calcium; 2008 Nov 22; 44(5):507-18. PubMed ID: 18440065
    [Abstract] [Full Text] [Related]

  • 10. Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake.
    Brunello L, Zampese E, Florean C, Pozzan T, Pizzo P, Fasolato C.
    J Cell Mol Med; 2009 Sep 22; 13(9B):3358-69. PubMed ID: 19382908
    [Abstract] [Full Text] [Related]

  • 11. Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment.
    Buxbaum JD, Choi EK, Luo Y, Lilliehook C, Crowley AC, Merriam DE, Wasco W.
    Nat Med; 1998 Oct 22; 4(10):1177-81. PubMed ID: 9771752
    [Abstract] [Full Text] [Related]

  • 12. A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein.
    Stabler SM, Ostrowski LL, Janicki SM, Monteiro MJ.
    J Cell Biol; 1999 Jun 14; 145(6):1277-92. PubMed ID: 10366599
    [Abstract] [Full Text] [Related]

  • 13. Ca2+-independent binding and cellular expression profiles question a significant role of calmyrin in transduction of Ca2+-signals to Alzheimer's disease-related presenilin 2 in forebrain.
    Blazejczyk M, Wojda U, Sobczak A, Spilker C, Bernstein HG, Gundelfinger ED, Kreutz MR, Kuznicki J.
    Biochim Biophys Acta; 2006 Jan 14; 1762(1):66-72. PubMed ID: 16257512
    [Abstract] [Full Text] [Related]

  • 14. Sorcin Activates the Brain PMCA and Blocks the Inhibitory Effects of Molecular Markers of Alzheimer's Disease on the Pump Activity.
    Berrocal M, Saez L, Mata AM.
    Int J Mol Sci; 2021 Jun 03; 22(11):. PubMed ID: 34205207
    [Abstract] [Full Text] [Related]

  • 15. Molecular dissection of domains in mutant presenilin 2 that mediate overproduction of amyloidogenic forms of amyloid beta peptides. Inability of truncated forms of PS2 with familial Alzheimer's disease mutation to increase secretion of Abeta42.
    Tomita T, Tokuhiro S, Hashimoto T, Aiba K, Saido TC, Maruyama K, Iwatsubo T.
    J Biol Chem; 1998 Aug 14; 273(33):21153-60. PubMed ID: 9694871
    [Abstract] [Full Text] [Related]

  • 16. Interaction of calcium/calmodulin-dependent protein kinase IIdeltaC with sorcin indirectly modulates ryanodine receptor function in cardiac myocytes.
    Anthony DF, Beattie J, Paul A, Currie S.
    J Mol Cell Cardiol; 2007 Oct 14; 43(4):492-503. PubMed ID: 17707398
    [Abstract] [Full Text] [Related]

  • 17. Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor.
    Franceschini S, Ilari A, Verzili D, Zamparelli C, Antaramian A, Rueda A, Valdivia HH, Chiancone E, Colotti G.
    FASEB J; 2008 Jan 14; 22(1):295-306. PubMed ID: 17699613
    [Abstract] [Full Text] [Related]

  • 18. Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.
    Genovese I, Giamogante F, Barazzuol L, Battista T, Fiorillo A, Vicario M, D'Alessandro G, Cipriani R, Limatola C, Rossi D, Sorrentino V, Poser E, Mosca L, Squitieri F, Perluigi M, Arena A, van Petegem F, Tito C, Fazi F, Giorgi C, Calì T, Ilari A, Colotti G.
    Cell Death Dis; 2020 Oct 15; 11(10):861. PubMed ID: 33060591
    [Abstract] [Full Text] [Related]

  • 19. Regulation of cardiac excitation-contraction coupling by sorcin, a novel modulator of ryanodine receptors.
    Farrell EF, Antaramian A, Benkusky N, Zhu X, Rueda A, Gómez AM, Valdivia HH.
    Biol Res; 2004 Oct 15; 37(4):609-12. PubMed ID: 15709688
    [Abstract] [Full Text] [Related]

  • 20. Calcium binding sequences in calmyrin regulates interaction with presenilin-2.
    Zhu J, Stabler SM, Ames JB, Baskakov I, Monteiro MJ.
    Exp Cell Res; 2004 Nov 01; 300(2):440-54. PubMed ID: 15475008
    [Abstract] [Full Text] [Related]

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