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237 related items for PubMed ID: 10755519

  • 1. Oral efficacy of the macrolide immunosuppressant SDZ RAD and of cyclosporine microemulsion in cynomolgus monkey kidney allotransplantation.
    Schuurman HJ, Ringers J, Schuler W, Slingerland W, Jonker M.
    Transplantation; 2000 Mar 15; 69(5):737-42. PubMed ID: 10755519
    [Abstract] [Full Text] [Related]

  • 2. Combined immunosuppression with cyclosporine (neoral) and SDZ RAD in non-human primate lung transplantation: systematic pharmacokinetic-based trials to improve efficacy and tolerability.
    Hausen B, Ikonen T, Briffa N, Berry GJ, Christians U, Robbins RC, Hook L, Serkova N, Benet LZ, Schuler W, Morris RE.
    Transplantation; 2000 Jan 15; 69(1):76-86. PubMed ID: 10653384
    [Abstract] [Full Text] [Related]

  • 3. Prevention of acute allograft rejection in nonhuman primate lung transplant recipients: induction with chimeric anti-interleukin-2 receptor monoclonal antibody improves the tolerability and potentiates the immunosuppressive activity of a regimen using low doses of both microemulsion cyclosporine and 40-O-(2-hydroxyethyl)-rapamycin.
    Hausen B, Gummert J, Berry GJ, Christians U, Serkova N, Ikonen T, Hook L, Legay F, Schuler W, Schreier MH, Morris RE.
    Transplantation; 2000 Feb 27; 69(4):488-96. PubMed ID: 10708100
    [Abstract] [Full Text] [Related]

  • 4. Suppression of acute rejection in allogeneic rat lung transplantation: a study of the efficacy and pharmacokinetics of rapamycin derivative (SDZ RAD) used alone and in combination with a microemulsion formulation of cyclosporine.
    Hausen B, Boeke K, Berry GJ, Segarra IT, Christians U, Morris RE.
    J Heart Lung Transplant; 1999 Feb 27; 18(2):150-9. PubMed ID: 10194039
    [Abstract] [Full Text] [Related]

  • 5. Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combination with cyclosporine or RAD.
    Schuurman HJ, Menninger K, Audet M, Kunkler A, Maurer C, Vedrine C, Bernhard M, Gaschen L, Brinkmann V, Quesniaux V.
    Transplantation; 2002 Oct 15; 74(7):951-60. PubMed ID: 12394836
    [Abstract] [Full Text] [Related]

  • 6. Tissue distribution and clinical monitoring of the novel macrolide immunosuppressant SDZ-RAD and its metabolites in monkey lung transplant recipients: interaction with cyclosporine.
    Serkova N, Hausen B, Berry GJ, Jacobsen W, Benet LZ, Morris RE, Christians U.
    J Pharmacol Exp Ther; 2000 Jul 15; 294(1):323-32. PubMed ID: 10871329
    [Abstract] [Full Text] [Related]

  • 7. Efficacy of SDZ RAD compared with CsA monotherapyand combined Rad/FTY720 treatment in a murine cardiac allotransplantation model.
    Nikolova Z, Hof A, Baumlin Y, Hof RP.
    Transpl Immunol; 2001 Oct 15; 9(1):43-9. PubMed ID: 11680571
    [Abstract] [Full Text] [Related]

  • 8. Successful treatment of acute, ongoing rat lung allograft rejection with the novel immunosuppressant SDZ-RAD.
    Hausen B, Boeke K, Berry GJ, Christians U, Schüler W, Morris RE.
    Ann Thorac Surg; 2000 Mar 15; 69(3):904-9. PubMed ID: 10750781
    [Abstract] [Full Text] [Related]

  • 9. SDZ RAD, a new rapamycin derivative: synergism with cyclosporine.
    Schuurman HJ, Cottens S, Fuchs S, Joergensen J, Meerloo T, Sedrani R, Tanner M, Zenke G, Schuler W.
    Transplantation; 1997 Jul 15; 64(1):32-5. PubMed ID: 9233697
    [Abstract] [Full Text] [Related]

  • 10. Early clinical experience with a novel rapamycin derivative.
    Nashan B.
    Ther Drug Monit; 2002 Feb 15; 24(1):53-8. PubMed ID: 11805723
    [Abstract] [Full Text] [Related]

  • 11. The macrolide SDZ RAD is efficacious in a nonhuman primate model of allotransplantation.
    Schuurman HJ, Schuler W, Ringers J, Jonker M.
    Transplant Proc; 1998 Aug 15; 30(5):2198-9. PubMed ID: 9723439
    [No Abstract] [Full Text] [Related]

  • 12. Coadministration of neoral and the novel rapamycin analog, SDZ RAD, to rat lung allograft recipients: potentiation of immunosuppressive efficacy and improvement of tolerability of staggered versus simultaneous treatment.
    Hausen B, Boeke K, Berry GJ, Segarra I, Benet LZ, Christians U, Morris RE.
    Transplantation; 1999 Apr 15; 67(7):956-62. PubMed ID: 10221478
    [Abstract] [Full Text] [Related]

  • 13. SDZ RAD, a new rapamycin derivative: pharmacological properties in vitro and in vivo.
    Schuler W, Sedrani R, Cottens S, Häberlin B, Schulz M, Schuurman HJ, Zenke G, Zerwes HG, Schreier MH.
    Transplantation; 1997 Jul 15; 64(1):36-42. PubMed ID: 9233698
    [Abstract] [Full Text] [Related]

  • 14. SDZ-RAD prevents manifestation of chronic rejection in rat renal allografts.
    Viklický O, Zou H, Müller V, Lacha J, Szabó A, Heemann U.
    Transplantation; 2000 Feb 27; 69(4):497-502. PubMed ID: 10708101
    [Abstract] [Full Text] [Related]

  • 15. Coadministration of either cyclosporine or steroids with humanized monoclonal antibodies against CD80 and CD86 successfully prolong allograft survival after life supporting renal transplantation in cynomolgus monkeys.
    Hausen B, Klupp J, Christians U, Higgins JP, Baumgartner RE, Hook LE, Friedrich S, Celnicker A, Morris RE.
    Transplantation; 2001 Sep 27; 72(6):1128-37. PubMed ID: 11579312
    [Abstract] [Full Text] [Related]

  • 16. The novel immunosuppressant FTY720 induces peripheral lymphodepletion of both T- and B-cells in cynomolgus monkeys when given alone, with Cyclosporine Neoral or with RAD.
    Quesniaux VF, Menninger K, Kunkler A, Vedrine C, Bernhard M, Hedinger R, Kraus G, Schuurman HJ.
    Transpl Immunol; 2000 Nov 27; 8(3):177-87. PubMed ID: 11147698
    [Abstract] [Full Text] [Related]

  • 17. RAD in de novo renal transplantation: comparison of three doses on the incidence and severity of acute rejection.
    Kahan BD, Kaplan B, Lorber MI, Winkler M, Cambon N, Boger RS.
    Transplantation; 2001 May 27; 71(10):1400-6. PubMed ID: 11391226
    [Abstract] [Full Text] [Related]

  • 18. Entry-into-human study with the novel immunosuppressant SDZ RAD in stable renal transplant recipients.
    Neumayer HH, Paradis K, Korn A, Jean C, Fritsche L, Budde K, Winkler M, Kliem V, Pichlmayr R, Hauser IA, Burkhardt K, Lison AE, Barndt I, Appel-Dingemanse S.
    Br J Clin Pharmacol; 1999 Nov 27; 48(5):694-703. PubMed ID: 10594471
    [Abstract] [Full Text] [Related]

  • 19. Differential effect of cyclosporine A and SDZ RAD on neointima formation of carotid allografts in apolipoprotein E-deficient mice.
    Matsumoto Y, Hof A, Baumlin Y, Hof RP.
    Transplantation; 2003 Oct 27; 76(8):1166-70. PubMed ID: 14578747
    [Abstract] [Full Text] [Related]

  • 20. The peripheral lymphocyte count predicts graft survival in DA to Lewis heterotopic heart transplantation treated with FTY720 and SDZ RAD.
    Nikolova Z, Hof A, Baumlin Y, Hof RP.
    Transpl Immunol; 2000 Jun 27; 8(2):115-24. PubMed ID: 11005317
    [Abstract] [Full Text] [Related]


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