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Journal Abstract Search

424 related items for PubMed ID: 10764145

  • 1. Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
    O'Gorman DM, McKenna SL, McGahon AJ, Knox KA, Cotter TG.
    Leukemia; 2000 Apr; 14(4):602-11. PubMed ID: 10764145
    [Abstract] [Full Text] [Related]

  • 2. A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
    Martelli AM, Tazzari PL, Tabellini G, Bortul R, Billi AM, Manzoli L, Ruggeri A, Conte R, Cocco L.
    Leukemia; 2003 Sep; 17(9):1794-805. PubMed ID: 12970779
    [Abstract] [Full Text] [Related]

  • 3. The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.
    Shimamura H, Terada Y, Okado T, Tanaka H, Inoshita S, Sasaki S.
    J Am Soc Nephrol; 2003 Jun; 14(6):1427-34. PubMed ID: 12761242
    [Abstract] [Full Text] [Related]

  • 4. Activation of PI3-kinase/PKB contributes to delay in neutrophil apoptosis after thermal injury.
    Hu Z, Sayeed MM.
    Am J Physiol Cell Physiol; 2005 May; 288(5):C1171-8. PubMed ID: 15625305
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor alpha in mice.
    Imose M, Nagaki M, Naiki T, Osawa Y, Brenner DA, Asano T, Hayashi H, Kato T, Moriwaki H.
    Liver Int; 2003 Oct; 23(5):386-96. PubMed ID: 14708901
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias.
    Zhao S, Konopleva M, Cabreira-Hansen M, Xie Z, Hu W, Milella M, Estrov Z, Mills GB, Andreeff M.
    Leukemia; 2004 Feb; 18(2):267-75. PubMed ID: 14628071
    [Abstract] [Full Text] [Related]

  • 7. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ.
    Cancer Res; 2003 Jan 15; 63(2):364-74. PubMed ID: 12543789
    [Abstract] [Full Text] [Related]

  • 8. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C, Rahmani M, Dai Y, Conrad D, Krystal G, Dent P, Grant S.
    Cancer Res; 2003 Apr 15; 63(8):1822-33. PubMed ID: 12702569
    [Abstract] [Full Text] [Related]

  • 9. Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells.
    Zhao Y, You H, Yang Y, Wei L, Zhang X, Yao L, Fan D, Yu Q.
    J Cell Biochem; 2004 Feb 15; 91(3):621-32. PubMed ID: 14755690
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.
    Uddin S, Hussain AR, Al-Hussein KA, Manogaran PS, Wickrema A, Gutierrez MI, Bhatia KG.
    Clin Cancer Res; 2005 Apr 15; 11(8):3102-8. PubMed ID: 15837766
    [Abstract] [Full Text] [Related]

  • 11. Apigenin and LY294002 prolong EGF-stimulated ERK1/2 activation in PC12 cells but are unable to induce full differentiation.
    Llorens F, Garcia L, Itarte E, Gómez N.
    FEBS Lett; 2002 Jan 16; 510(3):149-53. PubMed ID: 11801244
    [Abstract] [Full Text] [Related]

  • 12. Constitutive NF-kappaB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway.
    Birkenkamp KU, Geugien M, Schepers H, Westra J, Lemmink HH, Vellenga E.
    Leukemia; 2004 Jan 16; 18(1):103-12. PubMed ID: 14574326
    [Abstract] [Full Text] [Related]

  • 13. PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways.
    Grandage VL, Gale RE, Linch DC, Khwaja A.
    Leukemia; 2005 Apr 16; 19(4):586-94. PubMed ID: 15703783
    [Abstract] [Full Text] [Related]

  • 14. Differential sensitivity to apoptosis between the human small and large intestinal mucosae: linkage with segment-specific regulation of BCL-2 homologs and involvement of signaling pathways.
    Gauthier R, Laprise P, Cardin E, Harnois C, Plourde A, Reed JC, Vézina A, Vachon PH.
    J Cell Biochem; 2001 Apr 16; 82(2):339-55. PubMed ID: 11527158
    [Abstract] [Full Text] [Related]

  • 15. Downstream effectors of oncogenic ras in multiple myeloma cells.
    Hu L, Shi Y, Hsu JH, Gera J, Van Ness B, Lichtenstein A.
    Blood; 2003 Apr 15; 101(8):3126-35. PubMed ID: 12515720
    [Abstract] [Full Text] [Related]

  • 16. Inhibitors of the PI3-kinase/Akt pathway induce mitotic catastrophe in non-small cell lung cancer cells.
    Hemström TH, Sandström M, Zhivotovsky B.
    Int J Cancer; 2006 Sep 01; 119(5):1028-38. PubMed ID: 16570272
    [Abstract] [Full Text] [Related]

  • 17. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.
    del Peso L, González-García M, Page C, Herrera R, Nuñez G.
    Science; 1997 Oct 24; 278(5338):687-9. PubMed ID: 9381178
    [Abstract] [Full Text] [Related]

  • 18. Mcl-1 is a common target of stem cell factor and interleukin-5 for apoptosis prevention activity via MEK/MAPK and PI-3K/Akt pathways.
    Huang HM, Huang CJ, Yen JJ.
    Blood; 2000 Sep 01; 96(5):1764-71. PubMed ID: 10961875
    [Abstract] [Full Text] [Related]

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  • 20. Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway.
    Bai RY, Ouyang T, Miething C, Morris SW, Peschel C, Duyster J.
    Blood; 2000 Dec 15; 96(13):4319-27. PubMed ID: 11110708
    [Abstract] [Full Text] [Related]

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