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Journal Abstract Search

244 related items for PubMed ID: 10772636

  • 1. Substrate-dependent effect of acetonitrile on human liver microsomal cytochrome P450 2C9 (CYP2C9) activity.
    Tang C, Shou M, Rodrigues AD.
    Drug Metab Dispos; 2000 May; 28(5):567-72. PubMed ID: 10772636
    [Abstract] [Full Text] [Related]

  • 2. Stimulation of tolbutamide hydroxylation by acetone and acetonitrile in human liver microsomes and in a cytochrome P-450 2C9-reconstituted system.
    Palamanda J, Feng WW, Lin CC, Nomeir AA.
    Drug Metab Dispos; 2000 Jan; 28(1):38-43. PubMed ID: 10611138
    [Abstract] [Full Text] [Related]

  • 3. Prediction of in vivo drug-drug interactions between tolbutamide and various sulfonamides in humans based on in vitro experiments.
    Komatsu K, Ito K, Nakajima Y, Kanamitsu Si, Imaoka S, Funae Y, Green CE, Tyson CA, Shimada N, Sugiyama Y.
    Drug Metab Dispos; 2000 Apr; 28(4):475-81. PubMed ID: 10725317
    [Abstract] [Full Text] [Related]

  • 4. Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor.
    Tang C, Shou M, Mei Q, Rushmore TH, Rodrigues AD.
    J Pharmacol Exp Ther; 2000 May; 293(2):453-9. PubMed ID: 10773015
    [Abstract] [Full Text] [Related]

  • 5. Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.
    Tang W, Stearns RA, Wang RW, Chiu SH, Baillie TA.
    Chem Res Toxicol; 1999 Feb; 12(2):192-9. PubMed ID: 10027798
    [Abstract] [Full Text] [Related]

  • 6. Cytochrome P4502C9 is the principal catalyst of racemic acenocoumarol hydroxylation reactions in human liver microsomes.
    Thijssen HH, Flinois JP, Beaune PH.
    Drug Metab Dispos; 2000 Nov; 28(11):1284-90. PubMed ID: 11038154
    [Abstract] [Full Text] [Related]

  • 7. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM, Wester MR, Aramsombatdee E, Raucy JL.
    Arch Biochem Biophys; 1998 May 01; 353(1):16-28. PubMed ID: 9578596
    [Abstract] [Full Text] [Related]

  • 8. Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase.
    Draper AJ, Hammock BD.
    Arch Biochem Biophys; 2000 Apr 01; 376(1):199-205. PubMed ID: 10729206
    [Abstract] [Full Text] [Related]

  • 9. Lansoprazole enantiomer activates human liver microsomal CYP2C9 catalytic activity in a stereospecific and substrate-specific manner.
    Liu KH, Kim MJ, Jung WM, Kang W, Cha IJ, Shin JG.
    Drug Metab Dispos; 2005 Feb 01; 33(2):209-13. PubMed ID: 15537834
    [Abstract] [Full Text] [Related]

  • 10. The "albumin effect" and in vitro-in vivo extrapolation: sequestration of long-chain unsaturated fatty acids enhances phenytoin hydroxylation by human liver microsomal and recombinant cytochrome P450 2C9.
    Rowland A, Elliot DJ, Knights KM, Mackenzie PI, Miners JO.
    Drug Metab Dispos; 2008 May 01; 36(5):870-7. PubMed ID: 18256202
    [Abstract] [Full Text] [Related]

  • 11. Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac.
    Shen S, Marchick MR, Davis MR, Doss GA, Pohl LR.
    Chem Res Toxicol; 1999 Feb 01; 12(2):214-22. PubMed ID: 10027801
    [Abstract] [Full Text] [Related]

  • 12. CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes.
    Wester MR, Lasker JM, Johnson EF, Raucy JL.
    Drug Metab Dispos; 2000 Mar 01; 28(3):354-9. PubMed ID: 10681382
    [Abstract] [Full Text] [Related]

  • 13. Relative quantities of catalytically active CYP 2C9 and 2C19 in human liver microsomes: application of the relative activity factor approach.
    Venkatakrishnan K, von Moltke LL, Greenblatt DJ.
    J Pharm Sci; 1998 Jul 01; 87(7):845-53. PubMed ID: 9649353
    [Abstract] [Full Text] [Related]

  • 14. Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6.
    Voorman RL, Payne NA, Wienkers LC, Hauer MJ, Sanders PE.
    Drug Metab Dispos; 2001 Jan 01; 29(1):41-7. PubMed ID: 11124228
    [Abstract] [Full Text] [Related]

  • 15. Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.
    Giancarlo GM, Venkatakrishnan K, Granda BW, von Moltke LL, Greenblatt DJ.
    Eur J Clin Pharmacol; 2001 Apr 01; 57(1):31-6. PubMed ID: 11372587
    [Abstract] [Full Text] [Related]

  • 16. Differential inhibitory effects of phenytoin, diclofenac, phenylbutazone and a series of sulfonamides on hepatic cytochrome P4502C activity in vitro, and correlation with some molecular descriptors in the dwarf goat (Caprus hircus aegagrus).
    Zweers-Zeilmaker WM, Horbach GJ, Witkamp RF.
    Xenobiotica; 1997 Aug 01; 27(8):769-80. PubMed ID: 9293615
    [Abstract] [Full Text] [Related]

  • 17. Cytochrome P4502C11 is a target of diclofenac covalent binding in rats.
    Shen S, Hargus SJ, Martin BM, Pohl LR.
    Chem Res Toxicol; 1997 Apr 01; 10(4):420-3. PubMed ID: 9114979
    [Abstract] [Full Text] [Related]

  • 18. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X, Wang JS, Kivistö KT, Neuvonen PJ, Backman JT.
    Br J Clin Pharmacol; 2001 Nov 01; 52(5):547-53. PubMed ID: 11736863
    [Abstract] [Full Text] [Related]

  • 19. Are there differences in the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9? A systematic investigation into inter-system extrapolation factors.
    Crewe HK, Barter ZE, Yeo KR, Rostami-Hodjegan A.
    Biopharm Drug Dispos; 2011 Sep 01; 32(6):303-18. PubMed ID: 21725985
    [Abstract] [Full Text] [Related]

  • 20. Polysaccharide peptides from Coriolus versicolor competitively inhibit tolbutamide 4-hydroxylation in specific human CYP2C9 isoform and pooled human liver microsomes.
    Yeung JH, Or PM.
    Phytomedicine; 2011 Oct 15; 18(13):1170-5. PubMed ID: 21757329
    [Abstract] [Full Text] [Related]

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