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Journal Abstract Search

272 related items for PubMed ID: 10775272

  • 1. Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation.
    Garcia-Barrio M, Dong J, Ufano S, Hinnebusch AG.
    EMBO J; 2000 Apr 17; 19(8):1887-99. PubMed ID: 10775272
    [Abstract] [Full Text] [Related]

  • 2. Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells.
    Sattlegger E, Hinnebusch AG.
    EMBO J; 2000 Dec 01; 19(23):6622-33. PubMed ID: 11101534
    [Abstract] [Full Text] [Related]

  • 3. Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2.
    Marton MJ, Vazquez de Aldana CR, Qiu H, Chakraburtty K, Hinnebusch AG.
    Mol Cell Biol; 1997 Aug 01; 17(8):4474-89. PubMed ID: 9234705
    [Abstract] [Full Text] [Related]

  • 4. GCN20, a novel ATP binding cassette protein, and GCN1 reside in a complex that mediates activation of the eIF-2 alpha kinase GCN2 in amino acid-starved cells.
    Vazquez de Aldana CR, Marton MJ, Hinnebusch AG.
    EMBO J; 1995 Jul 03; 14(13):3184-99. PubMed ID: 7621831
    [Abstract] [Full Text] [Related]

  • 5. YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed.
    Sattlegger E, Swanson MJ, Ashcraft EA, Jennings JL, Fekete RA, Link AJ, Hinnebusch AG.
    J Biol Chem; 2004 Jul 16; 279(29):29952-62. PubMed ID: 15126500
    [Abstract] [Full Text] [Related]

  • 6. Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation.
    Sattlegger E, Hinnebusch AG.
    J Biol Chem; 2005 Apr 22; 280(16):16514-21. PubMed ID: 15722345
    [Abstract] [Full Text] [Related]

  • 7. GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.
    Marton MJ, Crouch D, Hinnebusch AG.
    Mol Cell Biol; 1993 Jun 22; 13(6):3541-56. PubMed ID: 8497269
    [Abstract] [Full Text] [Related]

  • 8. Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2.
    Kubota H, Ota K, Sakaki Y, Ito T.
    J Biol Chem; 2001 May 18; 276(20):17591-6. PubMed ID: 11350982
    [Abstract] [Full Text] [Related]

  • 9. Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation.
    Visweswaraiah J, Lee SJ, Hinnebusch AG, Sattlegger E.
    J Biol Chem; 2012 Nov 02; 287(45):37757-68. PubMed ID: 22888004
    [Abstract] [Full Text] [Related]

  • 10. Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases.
    Ramirez M, Wek RC, Vazquez de Aldana CR, Jackson BM, Freeman B, Hinnebusch AG.
    Mol Cell Biol; 1992 Dec 02; 12(12):5801-15. PubMed ID: 1448107
    [Abstract] [Full Text] [Related]

  • 11. GI domain-mediated association of the eukaryotic initiation factor 2alpha kinase GCN2 with its activator GCN1 is required for general amino acid control in budding yeast.
    Kubota H, Sakaki Y, Ito T.
    J Biol Chem; 2000 Jul 07; 275(27):20243-6. PubMed ID: 10801780
    [Abstract] [Full Text] [Related]

  • 12. Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.
    Cambiaghi TD, Pereira CM, Shanmugam R, Bolech M, Wek RC, Sattlegger E, Castilho BA.
    Biochem Biophys Res Commun; 2014 Jan 10; 443(2):592-7. PubMed ID: 24333428
    [Abstract] [Full Text] [Related]

  • 13. Evidence that Yih1 resides in a complex with ribosomes.
    Waller T, Lee SJ, Sattlegger E.
    FEBS J; 2012 May 10; 279(10):1761-76. PubMed ID: 22404850
    [Abstract] [Full Text] [Related]

  • 14. Differential requirements for P stalk components in activating yeast protein kinase Gcn2 by stalled ribosomes during stress.
    Gupta R, Hinnebusch AG.
    Proc Natl Acad Sci U S A; 2023 Apr 18; 120(16):e2300521120. PubMed ID: 37043534
    [Abstract] [Full Text] [Related]

  • 15. The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids.
    Wek SA, Zhu S, Wek RC.
    Mol Cell Biol; 1995 Aug 18; 15(8):4497-506. PubMed ID: 7623840
    [Abstract] [Full Text] [Related]

  • 16. Gcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2.
    Lee SJ, Swanson MJ, Sattlegger E.
    Biochem J; 2015 Mar 15; 466(3):547-59. PubMed ID: 25437641
    [Abstract] [Full Text] [Related]

  • 17. Mutations that bypass tRNA binding activate the intrinsically defective kinase domain in GCN2.
    Qiu H, Hu C, Dong J, Hinnebusch AG.
    Genes Dev; 2002 May 15; 16(10):1271-80. PubMed ID: 12023305
    [Abstract] [Full Text] [Related]

  • 18. Arabidopsis nonresponding to oxylipins locus NOXY7 encodes a yeast GCN1 homolog that mediates noncanonical translation regulation and stress adaptation.
    Izquierdo Y, Kulasekaran S, Benito P, López B, Marcos R, Cascón T, Hamberg M, Castresana C.
    Plant Cell Environ; 2018 Jun 15; 41(6):1438-1452. PubMed ID: 29499090
    [Abstract] [Full Text] [Related]

  • 19. Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity.
    Visweswaraiah J, Lageix S, Castilho BA, Izotova L, Kinzy TG, Hinnebusch AG, Sattlegger E.
    J Biol Chem; 2011 Oct 21; 286(42):36568-79. PubMed ID: 21849502
    [Abstract] [Full Text] [Related]

  • 20. Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
    Pochopien AA, Beckert B, Kasvandik S, Berninghausen O, Beckmann R, Tenson T, Wilson DN.
    Proc Natl Acad Sci U S A; 2021 Apr 06; 118(14):. PubMed ID: 33790014
    [Abstract] [Full Text] [Related]

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