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391 related items for PubMed ID: 10777583

  • 1. SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130.
    Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F.
    J Biol Chem; 2000 Apr 28; 275(17):12848-56. PubMed ID: 10777583
    [Abstract] [Full Text] [Related]

  • 2. Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2.
    Fairlie WD, De Souza D, Nicola NA, Baca M.
    Biochem J; 2003 Jun 01; 372(Pt 2):495-502. PubMed ID: 12593670
    [Abstract] [Full Text] [Related]

  • 3. SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130.
    Lehmann U, Schmitz J, Weissenbach M, Sobota RM, Hortner M, Friederichs K, Behrmann I, Tsiaris W, Sasaki A, Schneider-Mergener J, Yoshimura A, Neel BG, Heinrich PC, Schaper F.
    J Biol Chem; 2003 Jan 03; 278(1):661-71. PubMed ID: 12403768
    [Abstract] [Full Text] [Related]

  • 4. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG, Schweigart J, Kehrmann J, Ehlting C, Schaper F, Heinrich PC, Häussinger D.
    J Immunol; 2003 Jul 01; 171(1):257-66. PubMed ID: 12817006
    [Abstract] [Full Text] [Related]

  • 5. The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling.
    Fischer P, Lehmann U, Sobota RM, Schmitz J, Niemand C, Linnemann S, Haan S, Behrmann I, Yoshimura A, Johnston JA, Müller-Newen G, Heinrich PC, Schaper F.
    Biochem J; 2004 Mar 01; 378(Pt 2):449-60. PubMed ID: 14611646
    [Abstract] [Full Text] [Related]

  • 6. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F, Gendo C, Eck M, Schmitz J, Grimm C, Anhuf D, Kerr IM, Heinrich PC.
    Biochem J; 1998 Nov 01; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [Abstract] [Full Text] [Related]

  • 7. Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation.
    Anhuf D, Weissenbach M, Schmitz J, Sobota R, Hermanns HM, Radtke S, Linnemann S, Behrmann I, Heinrich PC, Schaper F.
    J Immunol; 2000 Sep 01; 165(5):2535-43. PubMed ID: 10946280
    [Abstract] [Full Text] [Related]

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  • 9. Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130.
    Nicholson SE, De Souza D, Fabri LJ, Corbin J, Willson TA, Zhang JG, Silva A, Asimakis M, Farley A, Nash AD, Metcalf D, Hilton DJ, Nicola NA, Baca M.
    Proc Natl Acad Sci U S A; 2000 Jun 06; 97(12):6493-8. PubMed ID: 10829066
    [Abstract] [Full Text] [Related]

  • 10. Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited.
    Friederichs K, Schmitz J, Weissenbach M, Heinrich PC, Schaper F.
    Eur J Biochem; 2001 Dec 06; 268(24):6401-7. PubMed ID: 11737194
    [Abstract] [Full Text] [Related]

  • 11. The tyrosine 974 within the LIF-R-chain of the gp130/LIF-R heteromeric receptor complex mediates negative regulation of LIF signalling.
    Clahsen T, Lehmann U, Stross C, Hermanns HM, Volkmer-Engert R, Schneider-Mergener J, Heinrich PC, Schaper F.
    Cell Signal; 2005 May 06; 17(5):559-69. PubMed ID: 15683731
    [Abstract] [Full Text] [Related]

  • 12. Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA.
    Terstegen L, Maassen BG, Radtke S, Behrmann I, Schaper F, Heinrich PC, Graeve L, Gatsios P.
    FEBS Lett; 2000 Jul 28; 478(1-2):100-4. PubMed ID: 10922477
    [Abstract] [Full Text] [Related]

  • 13. Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.
    Novotny-Diermayr V, Lin B, Gu L, Cao X.
    J Biol Chem; 2005 Apr 01; 280(13):12747-57. PubMed ID: 15677447
    [Abstract] [Full Text] [Related]

  • 14. SOCS-1, -2, -3: selective targets and functions downstream of the prolactin receptor.
    Tomic S, Chughtai N, Ali S.
    Mol Cell Endocrinol; 1999 Dec 20; 158(1-2):45-54. PubMed ID: 10630404
    [Abstract] [Full Text] [Related]

  • 15. Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.
    Kim H, Baumann H.
    Mol Cell Biol; 1999 Aug 20; 19(8):5326-38. PubMed ID: 10409724
    [Abstract] [Full Text] [Related]

  • 16. Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes.
    Nakaoka Y, Nishida K, Fujio Y, Izumi M, Terai K, Oshima Y, Sugiyama S, Matsuda S, Koyasu S, Yamauchi-Takihara K, Hirano T, Kawase I, Hirota H.
    Circ Res; 2003 Aug 08; 93(3):221-9. PubMed ID: 12855672
    [Abstract] [Full Text] [Related]

  • 17. Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases.
    Sommer U, Schmid C, Sobota RM, Lehmann U, Stevenson NJ, Johnston JA, Schaper F, Heinrich PC, Haan S.
    J Biol Chem; 2005 Sep 09; 280(36):31478-88. PubMed ID: 16000307
    [Abstract] [Full Text] [Related]

  • 18. Independent roles of SOCS-3 and SHP-2 in the regulation of neuronal gene expression by leukemia inhibitory factor.
    Bartoe JL, Nathanson NM.
    Brain Res Mol Brain Res; 2002 Nov 15; 107(2):108-19. PubMed ID: 12425940
    [Abstract] [Full Text] [Related]

  • 19. Different protein turnover of interleukin-6-type cytokine signalling components.
    Siewert E, Müller-Esterl W, Starr R, Heinrich PC, Schaper F.
    Eur J Biochem; 1999 Oct 01; 265(1):251-7. PubMed ID: 10491180
    [Abstract] [Full Text] [Related]

  • 20. Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy.
    Podewski EK, Hilfiker-Kleiner D, Hilfiker A, Morawietz H, Lichtenberg A, Wollert KC, Drexler H.
    Circulation; 2003 Feb 18; 107(6):798-802. PubMed ID: 12591746
    [Abstract] [Full Text] [Related]

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