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Journal Abstract Search

185 related items for PubMed ID: 10777608

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  • 4. The QTK loop is essential for the communication between the N-terminal atpase domain and the central cleavage--ligation region in human topoisomerase IIalpha.
    Bendsen S, Oestergaard VH, Skouboe C, Brinch M, Knudsen BR, Andersen AH.
    Biochemistry; 2009 Jul 14; 48(27):6508-15. PubMed ID: 19485418
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  • 5. Characterisation of the DNA-dependent ATPase activity of human DNA topoisomerase IIbeta: mutation of Ser165 in the ATPase domain reduces the ATPase activity and abolishes the in vivo complementation ability.
    West KL, Turnbull RM, Willmore E, Lakey JH, Austin CA.
    Nucleic Acids Res; 2002 Dec 15; 30(24):5416-24. PubMed ID: 12490710
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  • 6. DNA cleavage and religation by human topoisomerase II alpha at high temperature.
    Bromberg KD, Osheroff N.
    Biochemistry; 2001 Jul 27; 40(28):8410-8. PubMed ID: 11444988
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  • 7. The p53 tumor suppressor stimulates the catalytic activity of human topoisomerase IIalpha by enhancing the rate of ATP hydrolysis.
    Kwon Y, Shin BS, Chung IK.
    J Biol Chem; 2000 Jun 16; 275(24):18503-10. PubMed ID: 10764786
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  • 8. The transducer domain is important for clamp operation in human DNA topoisomerase IIalpha.
    Oestergaard VH, Bjergbaek L, Skouboe C, Giangiacomo L, Knudsen BR, Andersen AH.
    J Biol Chem; 2004 Jan 16; 279(3):1684-91. PubMed ID: 14583603
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  • 10. The N-terminal domain of human topoisomerase IIalpha is a DNA-dependent ATPase.
    Gardiner LP, Roper DI, Hammonds TR, Maxwell A.
    Biochemistry; 1998 Dec 01; 37(48):16997-7004. PubMed ID: 9836594
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  • 11. Mutagenesis of E477 or K505 in the B' domain of human topoisomerase II beta increases the requirement for magnesium ions during strand passage.
    West KL, Meczes EL, Thorn R, Turnbull RM, Marshall R, Austin CA.
    Biochemistry; 2000 Feb 15; 39(6):1223-33. PubMed ID: 10684600
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  • 12. A human topoisomerase II alpha heterodimer with only one ATP binding site can go through successive catalytic cycles.
    Skouboe C, Bjergbaek L, Oestergaard VH, Larsen MK, Knudsen BR, Andersen AH.
    J Biol Chem; 2003 Feb 21; 278(8):5768-74. PubMed ID: 12480934
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  • 13. Stability of the topoisomerase II closed clamp conformation may influence DNA-stimulated ATP hydrolysis.
    Vaughn J, Huang S, Wessel I, Sorensen TK, Hsieh T, Jensen LH, Jensen PB, Sehested M, Nitiss JL.
    J Biol Chem; 2005 Mar 25; 280(12):11920-9. PubMed ID: 15647268
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  • 14. Catalysis of ATP hydrolysis by two NH(2)-terminal fragments of yeast DNA topoisomerase II.
    Olland S, Wang JC.
    J Biol Chem; 1999 Jul 30; 274(31):21688-94. PubMed ID: 10419479
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  • 15. gyrB-225, a mutation of DNA gyrase that compensates for topoisomerase I deficiency: investigation of its low activity and quinolone hypersensitivity.
    Heddle JG, Lu T, Zhao X, Drlica K, Maxwell A.
    J Mol Biol; 2001 Jun 22; 309(5):1219-31. PubMed ID: 11399091
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  • 16. Analysis of etoposide binding to subdomains of human DNA topoisomerase II alpha in the absence of DNA.
    Leroy D, Kajava AV, Frei C, Gasser SM.
    Biochemistry; 2001 Feb 13; 40(6):1624-34. PubMed ID: 11327821
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  • 17. Mutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate.
    Bender RP, Osheroff N.
    Chem Res Toxicol; 2007 Jun 13; 20(6):975-81. PubMed ID: 17516663
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  • 18. DNA topoisomerases as targets for the anticancer drug TAS-103: DNA interactions and topoisomerase catalytic inhibition.
    Fortune JM, Velea L, Graves DE, Utsugi T, Yamada Y, Osheroff N.
    Biochemistry; 1999 Nov 23; 38(47):15580-6. PubMed ID: 10569942
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  • 19. Investigating the role of the latch in the positive supercoiling mechanism of reverse gyrase.
    Rodríguez AC.
    Biochemistry; 2003 May 27; 42(20):5993-6004. PubMed ID: 12755601
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  • 20. Interdomain communication in DNA topoisomerase II. DNA binding and enzyme activation.
    Mueller-Planitz F, Herschlag D.
    J Biol Chem; 2006 Aug 18; 281(33):23395-404. PubMed ID: 16782968
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