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Journal Abstract Search

480 related items for PubMed ID: 10778989

  • 1. Homocamptothecin, an E-ring-modified camptothecin, exerts more potent antiproliferative activity than other topoisomerase I inhibitors in human colon cancers obtained from surgery and maintained in vitro under histotypical culture conditions.
    Philippart P, Harper L, Chaboteaux C, Decaestecker C, Bronckart Y, Gordover L, Lesueur-Ginot L, Malonne H, Lavergne O, Bigg DC, da Costa PM, Kiss R.
    Clin Cancer Res; 2000 Apr; 6(4):1557-62. PubMed ID: 10778989
    [Abstract] [Full Text] [Related]

  • 2. Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.
    Bailly C, Lansiaux A, Dassonneville L, Demarquay D, Coulomb H, Huchet M, Lavergne O, Bigg DC.
    Biochemistry; 1999 Nov 23; 38(47):15556-63. PubMed ID: 10569939
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  • 3. A novel B-ring modified homocamptothecin, 12-Cl-hCPT, showing antiproliferative and topoisomerase I inhibitory activities superior to SN-38.
    Bailly C, Laine W, Baldeyrou B, Demarquay D, Huchet M, Coulomb H, Lanco C, Lavergne O, Bigg DC.
    Anticancer Drug Des; 2001 Feb 23; 16(1):27-36. PubMed ID: 11762642
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  • 5. Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.
    Lesueur-Ginot L, Demarquay D, Kiss R, Kasprzyk PG, Dassonneville L, Bailly C, Camara J, Lavergne O, Bigg DC.
    Cancer Res; 1999 Jun 15; 59(12):2939-43. PubMed ID: 10383158
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  • 8. Unusual potency of BN 80915, a novel fluorinated E-ring modified camptothecin, toward human colon carcinoma cells.
    Larsen AK, Gilbert C, Chyzak G, Plisov SY, Naguibneva I, Lavergne O, Lesueur-Ginot L, Bigg DC.
    Cancer Res; 2001 Apr 01; 61(7):2961-7. PubMed ID: 11306474
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  • 9. CPT-11 converting carboxylesterase and topoisomerase activities in tumour and normal colon and liver tissues.
    Guichard S, Terret C, Hennebelle I, Lochon I, Chevreau P, Frétigny E, Selves J, Chatelut E, Bugat R, Canal P.
    Br J Cancer; 1999 May 01; 80(3-4):364-70. PubMed ID: 10408839
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  • 10. Antiproliferative activity of the topoisomerase I inhibitors topotecan and camptothecin, on sub- and postconfluent tumor cell cultures.
    Pizao PE, Smitskamp-Wilms E, Van Ark-Otte J, Beijnen JH, Peters GJ, Pinedo HM, Giaccone G.
    Biochem Pharmacol; 1994 Sep 15; 48(6):1145-54. PubMed ID: 7945408
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  • 11. Cross-resistance of topoisomerase I and II inhibitors in neuroblastoma cell lines.
    Keshelava N, Groshen S, Reynolds CP.
    Cancer Chemother Pharmacol; 2000 Sep 15; 45(1):1-8. PubMed ID: 10647494
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  • 12. Strategies Targeting DNA Topoisomerase I in Cancer Chemotherapy: Camptothecins, Nanocarriers for Camptothecins, Organic Non-Camptothecin Compounds and Metal Complexes.
    Gokduman K.
    Curr Drug Targets; 2016 Sep 15; 17(16):1928-1939. PubMed ID: 27138759
    [Abstract] [Full Text] [Related]

  • 13. Characterization of novel human leukemic cell lines selected for resistance to merbarone, a catalytic inhibitor of DNA topoisomerase II.
    Kusumoto H, Rodgers QE, Boege F, Raimondi SC, Beck WT.
    Cancer Res; 1996 Jun 01; 56(11):2573-83. PubMed ID: 8653700
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  • 14. Synergistic cytotoxicity of topoisomerase I inhibitors with alkylating agents and etoposide in human brain tumor cell lines.
    Janss AJ, Cnaan A, Zhao H, Shpilsky A, Levow C, Sutton L, Phillips PC.
    Anticancer Drugs; 1998 Aug 01; 9(7):641-52. PubMed ID: 9773809
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  • 15. Topoisomerase I-mediated antiproliferative activity of enantiomerically pure fluorinated homocamptothecins.
    Lavergne O, Demarquay D, Bailly C, Lanco C, Rolland A, Huchet M, Coulomb H, Muller N, Baroggi N, Camara J, Le Breton C, Manginot E, Cazaux JB, Bigg DC.
    J Med Chem; 2000 Jun 01; 43(11):2285-9. PubMed ID: 10841808
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological evaluation of new homocamptothecin analogs.
    Luo Y, Yu S, Tong L, Huang Q, Lu W, Chen Y.
    Eur J Med Chem; 2012 Aug 01; 54():281-6. PubMed ID: 22647222
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  • 17. Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II.
    Utsugi T, Aoyagi K, Asao T, Okazaki S, Aoyagi Y, Sano M, Wierzba K, Yamada Y.
    Jpn J Cancer Res; 1997 Oct 01; 88(10):992-1002. PubMed ID: 9414662
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  • 18. Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors.
    Zhu L, Zhang X, Lei N, Liu W, Miao Z, Zhuang C, Sheng C, Guo W, Dong G, Yao J, Cheng P, Zhang W.
    Chem Biodivers; 2012 Jun 01; 9(6):1084-94. PubMed ID: 22700227
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  • 19. CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants.
    Jansen WJ, Zwart B, Hulscher ST, Giaccone G, Pinedo HM, Boven E.
    Int J Cancer; 1997 Jan 27; 70(3):335-40. PubMed ID: 9033637
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  • 20. The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux.
    Erlichman C, Boerner SA, Hallgren CG, Spieker R, Wang XY, James CD, Scheffer GL, Maliepaard M, Ross DD, Bible KC, Kaufmann SH.
    Cancer Res; 2001 Jan 15; 61(2):739-48. PubMed ID: 11212277
    [Abstract] [Full Text] [Related]

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