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300 related items for PubMed ID: 10785598
1. Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed. Peters GJ, van Triest B, Backus HH, Kuiper CM, van der Wilt CL, Pinedo HM. Eur J Cancer; 2000 May; 36(7):916-24. PubMed ID: 10785598 [Abstract] [Full Text] [Related]
2. Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates. Backus HH, Pinedo HM, Wouters D, Kuiper CM, Jansen G, van Groeningen CJ, Peters GJ. Oncol Res; 2000 May; 12(5):231-9. PubMed ID: 11417748 [Abstract] [Full Text] [Related]
9. Combination studies of antifolates with 5-fluorouracil in colon cancer cell lines. van der Wilt CL, Kuiper CM, Peters GJ. Oncol Res; 1999 Apr; 11(8):383-91. PubMed ID: 10803742 [Abstract] [Full Text] [Related]
10. The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates. Longley DB, Boyer J, Allen WL, Latif T, Ferguson PR, Maxwell PJ, McDermott U, Lynch M, Harkin DP, Johnston PG. Cancer Res; 2002 May 01; 62(9):2644-9. PubMed ID: 11980662 [Abstract] [Full Text] [Related]
13. Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status. Violette S, Poulain L, Dussaulx E, Pepin D, Faussat AM, Chambaz J, Lacorte JM, Staedel C, Lesuffleur T. Int J Cancer; 2002 Apr 01; 98(4):498-504. PubMed ID: 11920608 [Abstract] [Full Text] [Related]
18. Biochemical mechanisms of interferon modulation of 5-fluorouracil activity in colon cancer cells. van der Wilt CL, Smid K, Aherne GW, Noordhuis P, Peters GJ. Eur J Cancer; 1997 Mar 01; 33(3):471-8. PubMed ID: 9155534 [Abstract] [Full Text] [Related]
19. A rationale for the clinical development of the thymidylate synthase inhibitor ZD9331 in ovarian and other solid tumours. Jackman AL, Melin CJ, Kimbell R, Brunton L, Aherne GW, Theti DS, Walton M. Biochim Biophys Acta; 2002 Jul 18; 1587(2-3):215-23. PubMed ID: 12084463 [Abstract] [Full Text] [Related]