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Journal Abstract Search


249 related items for PubMed ID: 10801840

  • 1. Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide.
    Nicole P, Lins L, Rouyer-Fessard C, Drouot C, Fulcrand P, Thomas A, Couvineau A, Martinez J, Brasseur R, Laburthe M.
    J Biol Chem; 2000 Aug 04; 275(31):24003-12. PubMed ID: 10801840
    [Abstract] [Full Text] [Related]

  • 2. Vasoactive intestinal polypeptide receptor VPAC(1) subtype is predominant in rat prostate membranes.
    Juarranz MG, De Neef P, Robberecht P.
    Prostate; 1999 Sep 15; 41(1):1-6. PubMed ID: 10440869
    [Abstract] [Full Text] [Related]

  • 3. Two basic residues of the h-VPAC1 receptor second transmembrane helix are essential for ligand binding and signal transduction.
    Solano RM, Langer I, Perret J, Vertongen P, Juarranz MG, Robberecht P, Waelbroeck M.
    J Biol Chem; 2001 Jan 12; 276(2):1084-8. PubMed ID: 11013258
    [Abstract] [Full Text] [Related]

  • 4. Development of selective agonists and antagonists for the human vasoactive intestinal polypeptide VPAC(2) receptor.
    Moreno D, Gourlet P, De Neef P, Cnudde J, Waelbroeck M, Robberecht P.
    Peptides; 2000 Oct 12; 21(10):1543-9. PubMed ID: 11068102
    [Abstract] [Full Text] [Related]

  • 5. Mutational analysis of the human vasoactive intestinal peptide receptor subtype VPAC(2): role of basic residues in the second transmembrane helix.
    Vertongen P, Solano RM, Perret J, Langer I, Robberecht P, Waelbroeck M.
    Br J Pharmacol; 2001 Aug 12; 133(8):1249-54. PubMed ID: 11498510
    [Abstract] [Full Text] [Related]

  • 6. Different vasoactive intestinal polypeptide receptor domains are involved in the selective recognition of two VPAC(2)-selective ligands.
    Juarranz MG, Van Rampelbergh J, Gourlet P, De Neef P, Cnudde J, Robberecht P, Waelbroeck M.
    Mol Pharmacol; 1999 Dec 12; 56(6):1280-7. PubMed ID: 10570056
    [Abstract] [Full Text] [Related]

  • 7. Evidence for a direct interaction between the Thr11 residue of vasoactive intestinal polypeptide and Tyr184 located in the first extracellular loop of the VPAC2 receptor.
    Nachtergael I, Vertongen P, Langer I, Perret J, Robberecht P, Waelbroeck M.
    Biochem J; 2003 Mar 15; 370(Pt 3):1003-9. PubMed ID: 12475394
    [Abstract] [Full Text] [Related]

  • 8. Elucidation of the vasoactive intestinal peptide pharmacophore for VPAC(2) receptors in human and rat and comparison to the pharmacophore for VPAC(1) receptors.
    Igarashi H, Ito T, Pradhan TK, Mantey SA, Hou W, Coy DH, Jensen RT.
    J Pharmacol Exp Ther; 2002 Nov 15; 303(2):445-60. PubMed ID: 12388623
    [Abstract] [Full Text] [Related]

  • 9. Creation of a selective antagonist and agonist of the rat VPAC(1) receptor using a combinatorial approach with vasoactive intestinal peptide 6-23 as template.
    Tams JW, Jorgensen RM, Holm A, Fahrenkrug J.
    Mol Pharmacol; 2000 Nov 15; 58(5):1035-41. PubMed ID: 11040051
    [Abstract] [Full Text] [Related]

  • 10. Localisation of VIP-binding sites exhibiting properties of VPAC receptors in chromaffin cells of rainbow trout (Oncorhynchus mykiss).
    Montpetit CJ, Shahsavarani A, Perry SF.
    J Exp Biol; 2003 Jun 15; 206(Pt 11):1917-27. PubMed ID: 12728013
    [Abstract] [Full Text] [Related]

  • 11. Elucidation of vasoactive intestinal peptide pharmacophore for VPAC(1) receptors in human, rat, and guinea pig.
    Igarashi H, Ito T, Hou W, Mantey SA, Pradhan TK, Ulrich CD, Hocart SJ, Coy DH, Jensen RT.
    J Pharmacol Exp Ther; 2002 Apr 15; 301(1):37-50. PubMed ID: 11907155
    [Abstract] [Full Text] [Related]

  • 12. Identification of a VIP-specific receptor in guinea pig tenia coli.
    Teng BQ, Grider JR, Murthy KS.
    Am J Physiol Gastrointest Liver Physiol; 2001 Sep 15; 281(3):G718-25. PubMed ID: 11518684
    [Abstract] [Full Text] [Related]

  • 13. Two tyrosine residues in the first transmembrane helix of the human vasoactive intestinal peptide receptors play a role in supporting the active conformation.
    Perret J, Vertongen P, Solano RM, Langer I, Cnudde J, Robberecht P, Waelbroeck M.
    Br J Pharmacol; 2002 Aug 15; 136(7):1042-8. PubMed ID: 12145104
    [Abstract] [Full Text] [Related]

  • 14. A cloned frog vasoactive intestinal polypeptide/pituitary adenylate cyclase-activating polypeptide receptor exhibits pharmacological and tissue distribution characteristics of both VPAC1 and VPAC2 receptors in mammals.
    Alexandre D, Anouar Y, Jegou S, Fournier A, Vaudry H.
    Endocrinology; 1999 Mar 15; 140(3):1285-93. PubMed ID: 10067855
    [Abstract] [Full Text] [Related]

  • 15. Distribution of the VPAC2 receptor in peripheral tissues of the mouse.
    Harmar AJ, Sheward WJ, Morrison CF, Waser B, Gugger M, Reubi JC.
    Endocrinology; 2004 Mar 15; 145(3):1203-10. PubMed ID: 14617572
    [Abstract] [Full Text] [Related]

  • 16. Characterization of a novel VPAC(1) selective agonist and identification of the receptor domains implicated in the carboxyl-terminal peptide recognition.
    Van Rampelbergh J, Juarranz MG, Perret J, Bondue A, Solano RM, Delporte C, De Neef P, Robberecht P, Waelbroeck M.
    Br J Pharmacol; 2000 Jun 15; 130(4):819-26. PubMed ID: 10864888
    [Abstract] [Full Text] [Related]

  • 17. Vasoactive intestinal polypeptide VPAC1 and VPAC2 receptor chimeras identify domains responsible for the specificity of ligand binding and activation.
    Juarranz MG, Van Rampelbergh J, Gourlet P, De Neef P, Cnudde J, Robberecht P, Waelbroeck M.
    Eur J Biochem; 1999 Oct 01; 265(1):449-56. PubMed ID: 10491203
    [Abstract] [Full Text] [Related]

  • 18. Serine 447 in the carboxyl tail of human VPAC1 receptor is crucial for agonist-induced desensitization but not internalization of the receptor.
    Marie JC, Rouyer-Fessard C, Couvineau A, Nicole P, Devaud H, El Benna J, Laburthe M.
    Mol Pharmacol; 2003 Dec 01; 64(6):1565-74. PubMed ID: 14645688
    [Abstract] [Full Text] [Related]

  • 19. Diffuse pharmacophoric domains of vasoactive intestinal peptide (VIP) and further insights into the interaction of VIP with the N-terminal ectodomain of human VPAC1 receptor by photoaffinity labeling with [Bpa6]-VIP.
    Tan YV, Couvineau A, Laburthe M.
    J Biol Chem; 2004 Sep 10; 279(37):38889-94. PubMed ID: 15247290
    [Abstract] [Full Text] [Related]

  • 20. Alanine scanning of VIP. Structure-function relationship for binding to human recombinant VPAC1 receptor.
    Nicole P, Rouyer-Fessard C, Couvineau A, Drouot C, Fulcrand P, Martinez J, Laburthe M.
    Ann N Y Acad Sci; 2000 Sep 10; 921():352-6. PubMed ID: 11193851
    [No Abstract] [Full Text] [Related]


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