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424 related items for PubMed ID: 10823821

  • 1. Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD).
    Wajant H, Haas E, Schwenzer R, Muhlenbeck F, Kreuz S, Schubert G, Grell M, Smith C, Scheurich P.
    J Biol Chem; 2000 Aug 11; 275(32):24357-66. PubMed ID: 10823821
    [Abstract] [Full Text] [Related]

  • 2. Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis.
    Harper N, Hughes M, MacFarlane M, Cohen GM.
    J Biol Chem; 2003 Jul 11; 278(28):25534-41. PubMed ID: 12721308
    [Abstract] [Full Text] [Related]

  • 3. Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway.
    Siegmund D, Mauri D, Peters N, Juo P, Thome M, Reichwein M, Blenis J, Scheurich P, Tschopp J, Wajant H.
    J Biol Chem; 2001 Aug 31; 276(35):32585-90. PubMed ID: 11384965
    [Abstract] [Full Text] [Related]

  • 4. NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.
    Kreuz S, Siegmund D, Scheurich P, Wajant H.
    Mol Cell Biol; 2001 Jun 31; 21(12):3964-73. PubMed ID: 11359904
    [Abstract] [Full Text] [Related]

  • 5. Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction.
    Wajant H, Johannes FJ, Haas E, Siemienski K, Schwenzer R, Schubert G, Weiss T, Grell M, Scheurich P.
    Curr Biol; 1998 Jan 15; 8(2):113-6. PubMed ID: 9427646
    [Abstract] [Full Text] [Related]

  • 6. Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression.
    Lüschen S, Ussat S, Scherer G, Kabelitz D, Adam-Klages S.
    J Biol Chem; 2000 Aug 11; 275(32):24670-8. PubMed ID: 10827087
    [Abstract] [Full Text] [Related]

  • 7. TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells.
    Kim YS, Schwabe RF, Qian T, Lemasters JJ, Brenner DA.
    Hepatology; 2002 Dec 11; 36(6):1498-508. PubMed ID: 12447876
    [Abstract] [Full Text] [Related]

  • 8. Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma.
    Okano H, Shiraki K, Inoue H, Kawakita T, Yamanaka T, Deguchi M, Sugimoto K, Sakai T, Ohmori S, Fujikawa K, Murata K, Nakano T.
    Lab Invest; 2003 Jul 11; 83(7):1033-43. PubMed ID: 12861043
    [Abstract] [Full Text] [Related]

  • 9. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.
    Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A.
    Immunity; 2000 Jun 11; 12(6):611-20. PubMed ID: 10894161
    [Abstract] [Full Text] [Related]

  • 10. Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling.
    Harper N, Hughes MA, Farrow SN, Cohen GM, MacFarlane M.
    J Biol Chem; 2003 Nov 07; 278(45):44338-47. PubMed ID: 12920112
    [Abstract] [Full Text] [Related]

  • 11. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2.
    Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, Krammer PH, Walczak H.
    Immunity; 2000 Jun 07; 12(6):599-609. PubMed ID: 10894160
    [Abstract] [Full Text] [Related]

  • 12. MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors.
    Tran SE, Holmstrom TH, Ahonen M, Kahari VM, Eriksson JE.
    J Biol Chem; 2001 May 11; 276(19):16484-90. PubMed ID: 11278665
    [Abstract] [Full Text] [Related]

  • 13. Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD.
    Thomas LR, Henson A, Reed JC, Salsbury FR, Thorburn A.
    J Biol Chem; 2004 Jul 30; 279(31):32780-5. PubMed ID: 15173180
    [Abstract] [Full Text] [Related]

  • 14. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway.
    Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L.
    Immunity; 1997 Dec 30; 7(6):821-30. PubMed ID: 9430227
    [Abstract] [Full Text] [Related]

  • 15. Protection against Fas-mediated and tumor necrosis factor receptor 1-mediated liver injury by blockade of FADD without loss of nuclear factor-kappaB activation.
    Seino K, Setoguchi Y, Ogino T, Kayagaki N, Akiba H, Nakano H, Taniguchi H, Takada Y, Yuzawa K, Todoroki T, Fukuchi Y, Yagita H, Okumura K, Fukao K.
    Ann Surg; 2001 Nov 30; 234(5):681-8. PubMed ID: 11685033
    [Abstract] [Full Text] [Related]

  • 16. The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL.
    Grunert M, Gottschalk K, Kapahnke J, Gündisch S, Kieser A, Jeremias I.
    Cell Death Dis; 2012 Oct 25; 3(10):e414. PubMed ID: 23096115
    [Abstract] [Full Text] [Related]

  • 17. Chemical sensitization and regulation of TRAIL-induced apoptosis in a panel of B-lymphocytic leukaemia cell lines.
    Kang J, Kisenge RR, Toyoda H, Tanaka S, Bu J, Azuma E, Komada Y.
    Br J Haematol; 2003 Dec 25; 123(5):921-32. PubMed ID: 14632785
    [Abstract] [Full Text] [Related]

  • 18. The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways.
    Kataoka T, Budd RC, Holler N, Thome M, Martinon F, Irmler M, Burns K, Hahne M, Kennedy N, Kovacsovics M, Tschopp J.
    Curr Biol; 2000 Jun 01; 10(11):640-8. PubMed ID: 10837247
    [Abstract] [Full Text] [Related]

  • 19. A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis.
    Hu S, Vincenz C, Buller M, Dixit VM.
    J Biol Chem; 1997 Apr 11; 272(15):9621-4. PubMed ID: 9092488
    [Abstract] [Full Text] [Related]

  • 20. The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors.
    Gil J, Esteban M.
    Oncogene; 2000 Jul 27; 19(32):3665-74. PubMed ID: 10951573
    [Abstract] [Full Text] [Related]

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