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401 related items for PubMed ID: 10825137

  • 1. Induction of apoptosis in leukemic cells by the reversible microtubule-disrupting agent 2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1 -one: protection by Bcl-2 and Bcl-X(L) and cell cycle arrest.
    Gajate C, Barasoain I, Andreu JM, Mollinedo F.
    Cancer Res; 2000 May 15; 60(10):2651-9. PubMed ID: 10825137
    [Abstract] [Full Text] [Related]

  • 2. Cytoplasmic microtubules in human neutrophil degranulation: reversible inhibition by the colchicine analogue 2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1- one.
    Mollinedo F, Nieto JM, Andreu JM.
    Mol Pharmacol; 1989 Oct 15; 36(4):547-55. PubMed ID: 2682203
    [Abstract] [Full Text] [Related]

  • 3. Selective induction of G2/M arrest and apoptosis in HL-60 by a potent anticancer agent, HMJ-38.
    Yang JS, Hour MJ, Kuo SC, Huang LJ, Lee MR.
    Anticancer Res; 2004 Oct 15; 24(3a):1769-78. PubMed ID: 15274354
    [Abstract] [Full Text] [Related]

  • 4. Modulation of mitogen-activated protein kinases and phosphorylation of Bcl-2 by vinblastine represent persistent forms of normal fluctuations at G2-M1.
    Fan M, Du L, Stone AA, Gilbert KM, Chambers TC.
    Cancer Res; 2000 Nov 15; 60(22):6403-7. PubMed ID: 11103805
    [Abstract] [Full Text] [Related]

  • 5. Reversible inhibition of microtubules and cell growth by the bicyclic colchicine analogue MTC.
    Díez JC, Avila J, Nieto JM, Andreu JM.
    Cell Motil Cytoskeleton; 1987 Nov 15; 7(2):178-86. PubMed ID: 3581187
    [Abstract] [Full Text] [Related]

  • 6. Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation.
    Xiao D, Pinto JT, Soh JW, Deguchi A, Gundersen GG, Palazzo AF, Yoon JT, Shirin H, Weinstein IB.
    Cancer Res; 2003 Oct 15; 63(20):6825-37. PubMed ID: 14583480
    [Abstract] [Full Text] [Related]

  • 7. Betuletol 3-methyl ether induces G(2)-M phase arrest and activates the sphingomyelin and MAPK pathways in human leukemia cells.
    Rubio S, Quintana J, Eiroa JL, Triana J, Estévez F.
    Mol Carcinog; 2010 Jan 15; 49(1):32-43. PubMed ID: 19676104
    [Abstract] [Full Text] [Related]

  • 8. NF-kappaB pathway is involved in griseofulvin-induced G2/M arrest and apoptosis in HL-60 cells.
    Uen YH, Liu DZ, Weng MS, Ho YS, Lin SY.
    J Cell Biochem; 2007 Aug 01; 101(5):1165-75. PubMed ID: 17226769
    [Abstract] [Full Text] [Related]

  • 9. The novel antimicrotubule agent cryptophycin 52 (LY355703) induces apoptosis via multiple pathways in human prostate cancer cells.
    Drew L, Fine RL, Do TN, Douglas GP, Petrylak DP.
    Clin Cancer Res; 2002 Dec 01; 8(12):3922-32. PubMed ID: 12473608
    [Abstract] [Full Text] [Related]

  • 10. 1-(3',4',5'-Trimethoxyphenyl)-3-(3'',4''-dimethoxy-2''-hydroxyphenyl)-propane with microtubule-depolymerizing ability induces G2/M phase arrest and apoptosis in HepG2 cells.
    Li S, Tai W, Li Y, Zhang L, Zhang W, Ma E, Li J.
    Chem Biol Interact; 2010 Oct 06; 188(1):161-70. PubMed ID: 20674558
    [Abstract] [Full Text] [Related]

  • 11. Overexpression of bcl-2 or bcl-XL fails to inhibit apoptosis mediated by a novel retinoid.
    Fontana JA, Sun RJ, Rishi AK, Dawson MI, Ordónez JV, Zhang Y, Tschang SH, Bhalla K, Han Z, Wyche J, Poirer G, Sheikh MS, Shroot B, Reichert U.
    Oncol Res; 1998 Oct 06; 10(6):313-24. PubMed ID: 9848102
    [Abstract] [Full Text] [Related]

  • 12. Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells.
    Hsu YL, Kuo PL, Lin LT, Lin CC.
    J Pharmacol Exp Ther; 2005 Apr 06; 313(1):333-44. PubMed ID: 15626723
    [Abstract] [Full Text] [Related]

  • 13. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo.
    Hsu YL, Cho CY, Kuo PL, Huang YT, Lin CC.
    J Pharmacol Exp Ther; 2006 Aug 06; 318(2):484-94. PubMed ID: 16632641
    [Abstract] [Full Text] [Related]

  • 14. Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis.
    Aranha O, Grignon R, Fernandes N, McDonnell TJ, Wood DP, Sarkar FH.
    Int J Oncol; 2003 Apr 06; 22(4):787-94. PubMed ID: 12632069
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of the mitogen activated protein kinase pathway potentiates radiation-induced cell killing via cell cycle arrest at the G2/M transition and independently of increased signaling by the JNK/c-Jun pathway.
    Cartee L, Vrana JA, Wang Z, Park JS, Birrer M, Fisher PB, Grant S, Dent P.
    Int J Oncol; 2000 Feb 06; 16(2):413-22. PubMed ID: 10639586
    [Abstract] [Full Text] [Related]

  • 16. Staurosporine-induced apoptosis in Chang liver cells is associated with down-regulation of Bcl-2 and Bcl-XL.
    Giuliano M, Bellavia G, Lauricella M, D'Anneo A, Vassallo B, Vento R, Tesoriere G.
    Int J Mol Med; 2004 Apr 06; 13(4):565-71. PubMed ID: 15010857
    [Abstract] [Full Text] [Related]

  • 17. Effects of soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity.
    Su SJ, Chow NH, Kung ML, Hung TC, Chang KL.
    Nutr Cancer; 2003 Apr 06; 45(1):113-23. PubMed ID: 12791511
    [Abstract] [Full Text] [Related]

  • 18. Induction of G2/M arrest, endoreduplication, and apoptosis by actin depolymerization agent pextenotoxin-2 in human leukemia cells, involving activation of ERK and JNK.
    Moon DO, Kim MO, Kang SH, Lee KJ, Heo MS, Choi KS, Choi YH, Kim GY.
    Biochem Pharmacol; 2008 Aug 01; 76(3):312-21. PubMed ID: 18571148
    [Abstract] [Full Text] [Related]

  • 19. The involvement of microtubular disruption in methylmercury-induced apoptosis in neuronal and nonneuronal cell lines.
    Miura K, Koide N, Himeno S, Nakagawa I, Imura N.
    Toxicol Appl Pharmacol; 1999 Nov 01; 160(3):279-88. PubMed ID: 10544062
    [Abstract] [Full Text] [Related]

  • 20. Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells.
    Hsu PC, Hung HC, Liao YF, Liu CC, Tsay GJ, Liu GY.
    Leuk Res; 2008 Oct 01; 32(10):1530-40. PubMed ID: 18339422
    [Abstract] [Full Text] [Related]

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