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Journal Abstract Search


187 related items for PubMed ID: 10833516

  • 1. A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells.
    Smith CC, Yu YX, Kulka M, Aurelian L.
    J Biol Chem; 2000 Aug 18; 275(33):25690-9. PubMed ID: 10833516
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  • 3. The novel protein kinase of the RR1 subunit of herpes simplex virus has autophosphorylation and transphosphorylation activity that differs in its ATP requirements for HSV-1 and HSV-2.
    Peng T, Hunter JR, Nelson JW.
    Virology; 1996 Feb 01; 216(1):184-96. PubMed ID: 8614985
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  • 5. The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for immediate-early gene expression and virus growth.
    Smith CC, Peng T, Kulka M, Aurelian L.
    J Virol; 1998 Nov 01; 72(11):9131-41. PubMed ID: 9765459
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  • 6. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway.
    Perkins D, Pereira EF, Gober M, Yarowsky PJ, Aurelian L.
    J Virol; 2002 Feb 01; 76(3):1435-49. PubMed ID: 11773417
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  • 7. Expression of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for virus growth and neoplastic transformation.
    Smith CC, Kulka M, Wymer JP, Chung TD, Aurelian L.
    J Gen Virol; 1992 Jun 01; 73 ( Pt 6)():1417-28. PubMed ID: 1318943
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  • 8. The protein kinase activity of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) fused to the extracellular domain of the epidermal growth factor receptor is ligand-inducible.
    Smith CC, Luo JH, Aurelian L.
    Virology; 1996 Mar 15; 217(2):425-34. PubMed ID: 8610433
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  • 9. The transmembrane helical segment but not the invariant lysine is required for the kinase activity of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10).
    Luo JH, Aurelian L.
    J Biol Chem; 1992 May 15; 267(14):9645-53. PubMed ID: 1315764
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  • 10. Protein kinase activity associated with the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10).
    Chung TD, Wymer JP, Smith CC, Kulka M, Aurelian L.
    J Virol; 1989 Aug 15; 63(8):3389-98. PubMed ID: 2545912
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  • 11. The transmembrane domain of the large subunit of HSV-2 ribonucleotide reductase (ICP10) is required for protein kinase activity and transformation-related signaling pathways that result in ras activation.
    Smith CC, Luo JH, Hunter JC, Ordonez JV, Aurelian L.
    Virology; 1994 May 01; 200(2):598-612. PubMed ID: 8178446
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  • 12. Ras-GAP binding and phosphorylation by herpes simplex virus type 2 RR1 PK (ICP10) and activation of the Ras/MEK/MAPK mitogenic pathway are required for timely onset of virus growth.
    Smith CC, Nelson J, Aurelian L, Gober M, Goswami BB.
    J Virol; 2000 Nov 01; 74(22):10417-29. PubMed ID: 11044086
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  • 14. Vaccine potential of a herpes simplex virus type 2 mutant deleted in the PK domain of the large subunit of ribonucleotide reductase (ICP10).
    Aurelian L, Kokuba H, Smith CC.
    Vaccine; 1999 Apr 09; 17(15-16):1951-63. PubMed ID: 10217594
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  • 19. A novel gene expressed in human keratinocytes with long-term in vitro growth potential is required for cell growth.
    Aurelian L, Smith CC, Winchurch R, Kulka M, Gyotoku T, Zaccaro L, Chrest FJ, Burnett JW.
    J Invest Dermatol; 2001 Feb 09; 116(2):286-95. PubMed ID: 11180006
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  • 20. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein Bag-1.
    Perkins D, Pereira EF, Aurelian L.
    J Virol; 2003 Jan 09; 77(2):1292-305. PubMed ID: 12502846
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