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267 related items for PubMed ID: 10835357

  • 1. Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid.
    Egea PF, Mitschler A, Rochel N, Ruff M, Chambon P, Moras D.
    EMBO J; 2000 Jun 01; 19(11):2592-601. PubMed ID: 10835357
    [Abstract] [Full Text] [Related]

  • 2. Effects of ligand binding on the association properties and conformation in solution of retinoic acid receptors RXR and RAR.
    Egea PF, Rochel N, Birck C, Vachette P, Timmins PA, Moras D.
    J Mol Biol; 2001 Mar 23; 307(2):557-76. PubMed ID: 11254382
    [Abstract] [Full Text] [Related]

  • 3. Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.
    Pogenberg V, Guichou JF, Vivat-Hannah V, Kammerer S, Pérez E, Germain P, de Lera AR, Gronemeyer H, Royer CA, Bourguet W.
    J Biol Chem; 2005 Jan 14; 280(2):1625-33. PubMed ID: 15528208
    [Abstract] [Full Text] [Related]

  • 4. The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights.
    Sato Y, Ramalanjaona N, Huet T, Potier N, Osz J, Antony P, Peluso-Iltis C, Poussin-Courmontagne P, Ennifar E, Mély Y, Dejaegere A, Moras D, Rochel N.
    PLoS One; 2010 Nov 30; 5(11):e15119. PubMed ID: 21152046
    [Abstract] [Full Text] [Related]

  • 5. Novel roles of retinoid X receptor (RXR) and RXR ligand in dynamically modulating the activity of the thyroid hormone receptor/RXR heterodimer.
    Li D, Yamada T, Wang F, Vulin AI, Samuels HH.
    J Biol Chem; 2004 Feb 27; 279(9):7427-37. PubMed ID: 14668324
    [Abstract] [Full Text] [Related]

  • 6. Mutational analysis reveals that all-trans-retinoic acid, 9-cis-retinoic acid, and antagonist interact with distinct binding determinants of RARalpha.
    Keidel S, Lamour FP, Apfel CM.
    J Biol Chem; 1997 Jul 18; 272(29):18267-72. PubMed ID: 9218465
    [Abstract] [Full Text] [Related]

  • 7. Analysis of ligand binding and protein dynamics of human retinoid X receptor alpha ligand-binding domain by nuclear magnetic resonance.
    Lu J, Cistola DP, Li E.
    Biochemistry; 2006 Feb 14; 45(6):1629-39. PubMed ID: 16460010
    [Abstract] [Full Text] [Related]

  • 8. Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor alpha.
    Tate BF, Allenby G, Janocha R, Kazmer S, Speck J, Sturzenbecker LJ, Abarzúa P, Levin AA, Grippo JF.
    Mol Cell Biol; 1994 Apr 14; 14(4):2323-30. PubMed ID: 8139538
    [Abstract] [Full Text] [Related]

  • 9. The isolation and characterization of purified heterocomplexes of recombinant retinoic acid receptor and retinoid X receptor ligand binding domains.
    Tian K, Norris AW, Lin CL, Li E.
    Biochemistry; 1997 May 13; 36(19):5669-76. PubMed ID: 9153406
    [Abstract] [Full Text] [Related]

  • 10. The ligand-binding domains of the thyroid hormone/retinoid receptor gene subfamily function in vivo to mediate heterodimerization, gene silencing, and transactivation.
    Qi JS, Desai-Yajnik V, Greene ME, Raaka BM, Samuels HH.
    Mol Cell Biol; 1995 Mar 13; 15(3):1817-25. PubMed ID: 7862171
    [Abstract] [Full Text] [Related]

  • 11. Ligand-dependent activation of transcription in vitro by retinoic acid receptor alpha/retinoid X receptor alpha heterodimers that mimics transactivation by retinoids in vivo.
    Dilworth FJ, Fromental-Ramain C, Remboutsika E, Benecke A, Chambon P.
    Proc Natl Acad Sci U S A; 1999 Mar 02; 96(5):1995-2000. PubMed ID: 10051583
    [Abstract] [Full Text] [Related]

  • 12. Endogenous retinoic acid receptor (RAR)-retinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid-responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers to confer ligand-dependent activation of hRAR beta 2/RARE (DR5).
    Xiao JH, Durand B, Chambon P, Voorhees JJ.
    J Biol Chem; 1995 Feb 17; 270(7):3001-11. PubMed ID: 7852380
    [Abstract] [Full Text] [Related]

  • 13. Ligand-dependent heterodimerization of thyroid hormone receptor and retinoid X receptor.
    Kakizawa T, Miyamoto T, Kaneko A, Yajima H, Ichikawa K, Hashizume K.
    J Biol Chem; 1997 Sep 19; 272(38):23799-804. PubMed ID: 9295326
    [Abstract] [Full Text] [Related]

  • 14. Defining the communication between agonist and coactivator binding in the retinoid X receptor α ligand binding domain.
    Boerma LJ, Xia G, Qui C, Cox BD, Chalmers MJ, Smith CD, Lobo-Ruppert S, Griffin PR, Muccio DD, Renfrow MB.
    J Biol Chem; 2014 Jan 10; 289(2):814-26. PubMed ID: 24187139
    [Abstract] [Full Text] [Related]

  • 15. Molecular recognition of agonist ligands by RXRs.
    Egea PF, Mitschler A, Moras D.
    Mol Endocrinol; 2002 May 10; 16(5):987-97. PubMed ID: 11981034
    [Abstract] [Full Text] [Related]

  • 16. Dynamics and ligand-induced solvent accessibility changes in human retinoid X receptor homodimer determined by hydrogen deuterium exchange and mass spectrometry.
    Yan X, Broderick D, Leid ME, Schimerlik MI, Deinzer ML.
    Biochemistry; 2004 Feb 03; 43(4):909-17. PubMed ID: 14744134
    [Abstract] [Full Text] [Related]

  • 17. Purification and crystallization of the human RXRalpha ligand-binding domain-9-cisRA complex.
    Egea PF, Moras D.
    Acta Crystallogr D Biol Crystallogr; 2001 Mar 03; 57(Pt 3):434-7. PubMed ID: 11223524
    [Abstract] [Full Text] [Related]

  • 18. Retinoid activation of retinoic acid receptor but not retinoid X receptor is sufficient to rescue lethal defect in retinoic acid synthesis.
    Mic FA, Molotkov A, Benbrook DM, Duester G.
    Proc Natl Acad Sci U S A; 2003 Jun 10; 100(12):7135-40. PubMed ID: 12782789
    [Abstract] [Full Text] [Related]

  • 19. Efficient transactivation by retinoic acid receptors in yeast requires retinoid X receptors.
    Heery DM, Zacharewski T, Pierrat B, Gronemeyer H, Chambon P, Losson R.
    Proc Natl Acad Sci U S A; 1993 May 01; 90(9):4281-5. PubMed ID: 8387213
    [Abstract] [Full Text] [Related]

  • 20. Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors.
    Gampe RT, Montana VG, Lambert MH, Miller AB, Bledsoe RK, Milburn MV, Kliewer SA, Willson TM, Xu HE.
    Mol Cell; 2000 Mar 01; 5(3):545-55. PubMed ID: 10882139
    [Abstract] [Full Text] [Related]

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